Search results for "1.00"

showing 10 items of 9941 documents

Angular Trapping of Anisometric Nano-Objects in a Fluid

2012

We demonstrate the ability to trap, levitate, and orient single anisometric nanoscale objects with high angular precision in a fluid. An electrostatic fluidic trap confines a spherical object at a spatial location defined by the minimum of the electrostatic system free energy. For an anisometric object and a potential well lacking angular symmetry, the system free energy can further strongly depend on the object's orientation in the trap. Engineering the morphology of the trap thus enables precise spatial and angular confinement of a single levitating nano-object, and the process can be massively parallelized. Since the physics of the trap depends strongly on the surface charge of the objec…

10120 Department of ChemistryOptics and Photonics3104 Condensed Matter PhysicsSilverMaterials scienceMacromolecular SubstancesSurface PropertiesStatic Electricity2210 Mechanical EngineeringMetal Nanoparticles1600 General ChemistryBioengineeringTrap (computing)OpticsOrientation (geometry)540 ChemistryNano-ElectrochemistryNanotechnologyScattering RadiationGeneral Materials ScienceFluidicsSurface chargeParticle Size1502 Bioengineeringbusiness.industryPhysicsMechanical EngineeringElectrostatic unitsDNAGeneral ChemistryCondensed Matter Physics2500 General Materials ScienceSymmetry (physics)KineticsHydrodynamicsLevitationAnisotropybusinessNano Letters
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Anthropoid versus strepsirhine status of the African Eocene primates Algeripithecus and Azibius: craniodental evidence.

2009

Recent fossil discoveries have demonstrated that Africa and Asia were epicentres for the origin and/or early diversification of the major living primate lineages, including both anthropoids (monkeys, apes and humans) and crown strepsirhine primates (lemurs, lorises and galagos). Competing hypotheses favouring either an African or Asian origin for anthropoids rank among the most hotly contested issues in paleoprimatology. The Afrocentric model for anthropoid origins rests heavily on the >45 Myr old fossil Algeripithecus minutus from Algeria, which is widely acknowledged to be one of the oldest known anthropoids. However, the phylogenetic position of Algeripithecus with respect to other p…

10207 Department of Anthropology010506 paleontologyAzibiusZoologyLemuractivity pattern1100 General Agricultural and Biological Sciences01 natural sciencesGeneral Biochemistry Genetics and Molecular Biology2300 General Environmental ScienceNocturnality03 medical and health sciencesSpecies Specificity1300 General Biochemistry Genetics and Molecular BiologyResearch articles2400 General Immunology and Microbiologybiology.animalAnimalsOdontometryPrimateCladePhylogenyprimate evolution030304 developmental biology0105 earth and related environmental sciencesGeneral Environmental Science[ SDU.STU.PG ] Sciences of the Universe [physics]/Earth Sciences/Paleontology0303 health sciencesGeneral Immunology and Microbiologybiology300 Social sciences sociology & anthropologyFossilsAlgeripithecus[SDV.BID.EVO]Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]StrepsirhiniHaplorhiniGeneral Medicinebiology.organism_classificationStrepsirhini[ SDV.BID.EVO ] Life Sciences [q-bio]/Biodiversity/Populations and Evolution [q-bio.PE]toothcombed primatesToothcombAlgeriaAfricaGeneral Agricultural and Biological Sciences[SDU.STU.PG]Sciences of the Universe [physics]/Earth Sciences/PaleontologyTooth
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Molecular characterization of Treponema pallidum subsp. pallidum in Switzerland and France with a new multilocus sequence typing scheme

2018

Syphilis is an important public health problem and an increasing incidence has been noted in recent years. Characterization of strain diversity through molecular data plays a critical role in the epidemiological understanding of this re-emergence. We here propose a new high-resolution multilocus sequence typing (MLST) scheme for Treponema pallidum subsp. pallidum (TPA). We analyzed 30 complete and draft TPA genomes obtained directly from clinical samples or from rabbit propagated strains to identify suitable typing loci and tested the new scheme on 120 clinical samples collected in Switzerland and France. Our analyses yielded three loci with high discriminatory power: TP0136, TP0548, and TP…

10207 Department of AnthropologyArtificial Gene Amplification and ExtensionGene mutationPathology and Laboratory MedicineFrance/epidemiologyBiochemistryPolymerase Chain Reactionlaw.inventionSwitzerland/epidemiologylcsh:SciencePhylogenyMammalsBacterialEukaryotaGeneral MedicineMacrolides/pharmacologyMultilocus Sequence Typing/methods3. Good healthBacterial PathogensNucleic acidsMedical MicrobiologyLeporidsMacrolidesAlleles; Anti-Bacterial Agents/pharmacology; DNA Bacterial/genetics; France/epidemiology; Genome Bacterial; Genotype; Globus Pallidus; Macrolides/pharmacology; Multilocus Sequence Typing/methods; Phylogeny; Polymorphism Single Nucleotide; RNA Ribosomal 23S/genetics; Sequence Analysis DNA/methods; Switzerland/epidemiology; Syphilis/epidemiology; Treponema pallidum/geneticsGeneral Agricultural and Biological SciencesSwitzerlandGenotypeSequence analysis030106 microbiologySexually Transmitted Diseases1100 General Agricultural and Biological SciencesGlobus PallidusMicrobiologyAnti-Bacterial Agents/pharmacology10127 Institute of Evolutionary Biology and Environmental Studies03 medical and health sciences1300 General Biochemistry Genetics and Molecular Biology23S ribosomal RNAGeneticsTypingSyphilisPolymorphismNon-coding RNAMolecular Biology TechniquesMicrobial PathogensMolecular BiologyAllelesRibosomal1000 MultidisciplinaryGenitourinary Infectionslcsh:ROrganismsBiology and Life SciencesDNATropical DiseasesTreponema pallidum/genetics030104 developmental biologyGenetic LociGeneral Biochemistrylcsh:QMultilocus Sequence Typing0301 basic medicineBacterial DiseasesBacterial/geneticslcsh:MedicineTreponematosesGeographical LocationslawGenotypeMedicine and Health Sciences23S/geneticsTreponema PallidumPolymerase chain reactionGeneticsMultidisciplinaryTreponemaGenome10177 Dermatology ClinicSingle NucleotideAnimal Models10218 Institute of Legal MedicineAnti-Bacterial AgentsDNA/methodsEuropeRNA Ribosomal 23SInfectious DiseasesRibosomal RNAExperimental Organism SystemsVertebratesFranceRabbitsPathogensSequence AnalysisResearch ArticleNeglected Tropical DiseasesDNA BacterialCell biologyCellular structures and organellesUrology610 Medicine & healthGenetics and Molecular BiologyBiologyResearch and Analysis MethodsPolymorphism Single NucleotideAnimalsEuropean Unionddc:613Syphilis/epidemiologySequence Analysis DNAbiology.organism_classificationddc:616.8People and PlacesAmniotesMultilocus sequence typingRNARibosomesGenome BacterialPLoS ONE
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Estimating the dwarfing rate of an extinct Sicilian elephant.

2021

Summary Evolution on islands, together with the often extreme phenotypic changes associated with it, has attracted much interest from evolutionary biologists. However, measuring the rate of change of phenotypic traits of extinct animals can be challenging, in part due to the incompleteness of the fossil record. Here, we use combined molecular and fossil evidence to define the minimum and maximum rate of dwarfing in an extinct Mediterranean dwarf elephant from Puntali Cave (Sicily). 1 Despite the challenges associated with recovering ancient DNA from warm climates, 2 we successfully retrieved a mitogenome from a sample with an estimated age between 175,500 and 50,000 years. Our results sugge…

11000301 basic medicineMediterranean climate1300Lineage (evolution)ElephantsExtinction BiologicalDNA MitochondrialGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciences0302 clinical medicineCaveAnimalsDNA AncientSicilyPhylogenygeographygeography.geographical_feature_categoryPalaeoloxodonbiologyFossils2800Phenotypic traitbiology.organism_classificationlanguage.human_languageDwarfing030104 developmental biologyAncient DNAEvolutionary biologylanguageGeneral Agricultural and Biological SciencesSicilian030217 neurology & neurosurgeryCurrent biology : CB
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Screening archaeological bone for palaeogenetic and palaeoproteomic studies.

2020

Funder: FP7 Ideas: European Research Council; funder-id: http://dx.doi.org/10.13039/100011199; Grant(s): 295729

1100Proteomics1300Social SciencesMarine and Aquatic Sciences01 natural sciencesBiochemistrySpectroscopy Fourier Transform InfraredLimnologyScreening method0303 health sciencesMultidisciplinaryAncient DNAChemistryFossilsQRFOS: Social sciencesNucleic acidsArchaeologyAttenuated total reflectionMedicinePhysical AnthropologyOrganic contentResearch Article1000010506 paleontologyScienceInfrared spectroscopyPaleoenvironmentsBone and Bones03 medical and health sciencesPaleoanthropologyGeneticsAnimalsHumansPaleolimnologyDNA AncientPaleozoology030304 developmental biology0105 earth and related environmental sciencesEcology and Environmental SciencesBiology and Life SciencesProteinsPaleontologyDNAArchaeologyEarth sciencesAncient DNAAnthropologyPaleobiologyPaleogeneticsCollagensPloS one
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A comparison of performance of Deca Iron and Triple Deca Iron ultra-triathletes

2014

This study intended to compare the performance of ultra-triathletes competing in a Deca Iron ultra-triathlon (i.e. 10 times 3.8 km swimming, 180 km cycling, and 42.2 km running) with the performance of athletes competing in a Triple Deca Iron ultra-triathlon (i.e. 30 times 3.8 km swimming, 180 km cycling, and 42.2 km running). Split and overall race times of six male finishers in a Deca Iron ultra-triathlon and eight male finishers in a Triple Deca Iron ultra-triathlon were analysed using multiple t-tests, linear and non-linear regression analyses, and analysis of variance. Among the 19 starters (i.e. 17 men and two women) in the Deca Iron ultra-triathlon, six men (i.e. 35.3% of all starter…

11035 Institute of General Practice1000 MultidisciplinaryMultidisciplinaryResearchCycling610 Medicine & healthTriathlonRunningUltra-enduranceAnimal scienceCyclingDeca-Ultra enduranceSimulationSwimmingMathematics
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Wheelchair half-marathon and marathon performance: The ‘Oita International Wheelchair Marathon’ 1983-2011

2013

Knechtle, B. & Lepers, R. (2013). Wheelchair half-marathon and marathon performance ‐ the ‘Oita International Wheelchair Marathon’ 1983-2011. J. Hum. Sport Exerc., 8(4), pp.974-985. We compared participation and performance trends of individuals with disabilities competing in the half- and full-marathon in the ‘Oita International Wheelchair Marathon’ from 1981 to 2011. The performance times decreased during the 1980’s until the middle 1990’s and stabilized thereafter for both half-marathoners and marathoners. The mean top five overall finishers times were 0:52±0:07 h:min for half-marathoners and 1:36 ±0:11 h:min for marathoners, respectively. The mean age of the finishers increased signific…

11035 Institute of General PracticeAge effectmedicine.medical_specialty610 Medicine & healthPhysical Therapy Sports Therapy and RehabilitationSpinal cord injuryEnduranceWheelchairPhysical medicine and rehabilitationHumEducación Física y DeportivaMedicine3612 Physical Therapy Sports Therapy and Rehabilitationlcsh:Sports medicineSpinal cord injurybiologyIndividuals with disabilitybusiness.industryAthletesMean agebiology.organism_classificationmedicine.diseaseAging athletesPhysical therapybusinesslcsh:RC1200-1245Journal of Human Sport and Exercise
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European dominance in multistage ultramarathons: an analysis of finisher rate and performance trends from 1992 to 2010

2013

Mohannad Abou Shoak,1 Beat Knechtle,1,2 Christoph Alexander Rüst,1 Romuald Lepers,3 Thomas Rosemann11Institute of General Practice and for Health Services Research, University of Zurich, Zurich, Switzerland; 2Gesundheitszentrum St Gallen, St Gallen, Switzerland; 3INSERM U1093, Faculty of Sport Sciences, University of Burgundy, Dijon, FranceBackground: Participation and performance trends regarding the nationality of ultraendurance athletes have been investigated in the triathlon, but not in running. The present study aimed to identify the countries in which multistage ultramarathons were held around the world and the nationalities of successful finishers.Methods: Finisher rates and…

11035 Institute of General PracticeFuture studiesOperations researchbusiness.industryrun610 Medicine & healthTotal fieldnationalitystagelanguage.human_languageultraenduranceGermanDominance (economics)languageNationalityMedicinelcsh:Sports medicinelcsh:RC1200-1245businessdistanceOpen Access Journal of Sports MedicineTourismDemographyOriginal ResearchOpen Access Journal of Sports Medicine
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Will women outrun men in ultra-marathon road races from 50 km to 1,000 km?

2014

Abstract It has been assumed that women would be able to outrun men in ultra-marathon running. The present study investigated the sex differences in running speed in ultra-marathons held worldwide from 50 km to 1,000 km. Changes in running speeds and the sex differences in running speeds in the annual fastest finishers in 50 km, 100 km, 200 km and 1,000 km events held worldwide from 1969–2012 were analysed using linear, non-linear and multi-level regression analyses. For the annual fastest and the annual ten fastest finishers, running speeds increased non-linearly in 50 km and 100 km, but not in 200 km and 1,000 km where running speeds remained unchanged for the annual fastest. The sex diff…

11035 Institute of General PracticeGerontologyUltra-marathon1000 MultidisciplinaryMultidisciplinaryResearch610 Medicine & health[ SDV.SPEE ] Life Sciences [q-bio]/Santé publique et épidémiologieUltra marathonRunning speedGeography[SDV.SPEE] Life Sciences [q-bio]/Santé publique et épidémiologieWomanMan[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieGender gapGender gapDemography
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The aspect of nationality and performance in a mountain ultra-marathon-the ‘Swiss Alpine Marathon’

2012

Eichenberger E, Knechtle B, Rust CA, Lepers R, Rosemann T, Onywera VO. The aspect of nationality and performance in a mountain ultra-marathon - the ‘Swiss Alpine Marathon’ J. Hum. Sport Exerc. Vol. 7, No. 4, pp. 748-762, 2012. Runners from East Africa and especially from Kenya dominate middle- and longdistance running races worldwide. The aim of the present study was to investigate the participation and performance trends regarding the nationality of runners in a mountain ultra-marathon held in partially high alpine terrain. We hypothesized that Kenyan runners, living and training in the Great Rift Valley, a predominantly hilly, mountainous and altitudinous region like the Alps, would domin…

11035 Institute of General PracticeKenyaAlpine ultra-runningEthnic groupPhysical Therapy Sports Therapy and Rehabilitation610 Medicine & healthUltra marathonGeographyHumEast africaEthnicityEducación Física y DeportivaNationalitylcsh:Sports medicine3612 Physical Therapy Sports Therapy and Rehabilitationlcsh:RC1200-1245SocioeconomicsUltra enduranceEndurance runningUltra endurance
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