Search results for "1000"

Will women outrun men in ultra-marathon road races from 50 km to 1,000 km?

2014

Abstract It has been assumed that women would be able to outrun men in ultra-marathon running. The present study investigated the sex differences in running speed in ultra-marathons held worldwide from 50 km to 1,000 km. Changes in running speeds and the sex differences in running speeds in the annual fastest finishers in 50 km, 100 km, 200 km and 1,000 km events held worldwide from 1969–2012 were analysed using linear, non-linear and multi-level regression analyses. For the annual fastest and the annual ten fastest finishers, running speeds increased non-linearly in 50 km and 100 km, but not in 200 km and 1,000 km where running speeds remained unchanged for the annual fastest. The sex diff…

Performance in Olympic triathlon: changes in performance of elite female and male triathletes in the ITU World Triathlon Series from 2009 to 2012

2013

Abstract This study investigated the changes in performance and sex difference in performance of the world best triathletes at the ITU (International Triathlon Union) World Triathlon Series (i.e. 1.5 km swimming, 40 km cycling and 10 km running) during the 2009-2012 period including the 2012 London Olympic Games. Changes in overall race times, split times and sex difference in performance of the top ten women and men of each race were analyzed using single and multi-level regression analyses. Swimming and running split times remained unchanged whereas cycling split times (ß = 0.003, P < 0.001) and overall race times (ß = 0.003, P < 0.001) increased significantly for both women and men…

The effects of course length on freestyle swimming speed in elite female and male swimmers - a comparison of swimmers at national and international l…

2013

Abstract Freestyle swimming performance over 50 m, 100 m, 200 m, 400 m, 800 m and 1,500 m was compared on short (25 m) and long (50 m) course for 92,196 national swimmers (i.e. annual high score list Switzerland) and 1,104 international swimmers (i.e. finalists FINA World Championships) from 2000 to 2012. National and international swimmers of both sexes were on average 2.0 ± 0.6% faster on short than on long course. Sex-related differences in swimming speed were greater on short than on long course for international and national swimmers from 50 m to 800 m. Freestyle swimming performance improved across years for international swimmers in both short- and long-course whereas only male natio…

Analysis of 10 km swimming performance of elite male and female open-water swimmers.

2013

Abstract This study investigated trends in performance and sex difference in swimming speed of elite open-water swimmers at FINA 10 km competitions (i.e. World Cup races, European Championships, World Championships and Olympic Games). Swimming speed and sex difference in swimming speed of the fastest and the top ten women and men per event competing at 10 km open-water races between 2008 and 2012 were analysed using single and multi-level regression analyses. A total of 2,591 swimmers (i.e. 1,120 women and 1,471 men) finished 47 races. Swimming speed of the fastest women (1.35 ± 0.9 m/s) and men (1.45 ± 0.10 m/s) showed no changes across years. The mean sex difference in swimming speed for …

The many faces of human sociality: uncovering the distribution and stability of social preferences

2018

There is vast heterogeneity in the human willingness to weigh others' interests in decision making. This heterogeneity concerns the motivational intricacies as well as the strength of other-regarding behaviors, and raises the question how one can parsimoniously model and characterize heterogeneity across several dimensions of social preferences while still being able to predict behavior over time and across situations. We tackle this task with an experiment and a structural model of preferences that allows us to simultaneously estimate outcome-based and reciprocity-based social preferences. We find that non-selfish preferences are the rule rather than the exception. Neither at the level of …

Elements of the Archean thermal history and apparent polar wander of the eastern Kaapvaal Craton, Swaziland, from single grain dating and paleomagnet…

1989

A meta-analysis of 120 246 individuals identifies 18 new loci for fibrinogen concentration

2015

Genome-wide association studies have previously identified 23 genetic loci associated with circulating fibrinogen concentration. These studies used HapMap imputation and did not examine the X-chromosome. 1000 Genomes imputation provides better coverage of uncommon variants, and includes indels. We conducted a genome-wide association analysis of 34 studies imputed to the 1000 Genomes Project reference panel and including similar to 120 000 participants of European ancestry (95 806 participants with data on the X-chromosome). Approximately 10.7 million single-nucleotide polymorphisms and 1.2 million indels were examined. We identified 41 genome-wide significant fibrinogen loci ; of which, 18 …

Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10

2014

The prevalence of allergic asthma and other atopic diseases has reached epidemic proportions in large parts of the developed world. The gradual loss of the human indigenous microbiota has been held responsible for this trend. The bacterial pathogen Helicobacter pylori is a constituent of the normal gastric microbiota whose presence has been inversely linked to allergy and asthma in humans and experimental models. Here we show that oral or i.p. tolerization with H. pylori extract prevents the airway hyperresponsiveness, bronchoalveolar eosinophilia, pulmonary inflammation, and Th2 cytokine production that are hallmarks of allergen-induced asthma in mice. Asthma protection is not conferred by…

El virus del Papiloma Humano en cavidad oral y orofaríngea en estudiantes universitarios de 18 a 25 años en Valencia

2017

INTRODUCCIÓN Y JUSTIFICACIÓN DEL ESTUDIO El VPH es una de las infecciones virales más extendidas en la población. Estudios epidemiológicos revelan que la infección oral por VPH juega un papel importante en el desarrollo de enfermedades precancerosas o cánceres de la cavidad oral, en particular en el cáncer de células escamosas orales.1 Aunque se han descrito más de 140 genotipos de VPH, no todos ellos tienen el mismo riesgo de provocar lesiones pre-malignas o cánceres. El genotipo VPH-16 está implicado en la mayoría de estas lesiones, aunque existen otros genotipos carcinogénico. Es una infección indetectable ya que, suele revertir de forma espontánea sin derivar en lesiones premalignas o m…

A comparative study of the physicochemical properties of iron isomaltoside 1000 (Monofer®), a new intravenous iron preparation and its clinical impli…

2011

Abstract The treatment of iron deficiency anemia with polynuclear iron formulations is an established therapy in patients with chronic kidney disease but also in other disease areas like gastroenterology, cardiology, oncology, pre/post operatively and obstetrics’ and gynecology. Parenteral iron formulations represent colloidal systems in the lower nanometer size range which have traditionally been shown to consist of an iron core surrounded by a carbohydrate shell. In this publication, we for the first time describe the novel matrix structure of iron isomaltoside 1000 which differs from the traditional picture of an iron core surrounded by a carbohydrate. Despite some structural similaritie…