Search results for "10b"

showing 10 items of 13 documents

Could CoRoT-7b and Kepler-10b be remnants of evaporated gas or ice giants?

2009

We present thermal mass loss calculations over evolutionary time scales for the investigation if the smallest transiting rocky exoplanets CoRoT-7b (∼1.68REarth) and Kepler-10b (∼1.416REarth) could be remnants of an initially more massive hydrogen-rich gas giant or a hot Neptune-class exoplanet. We apply a thermal mass loss formula which yields results that are comparable to hydrodynamic loss models. Our approach considers the effect of the Roche lobe, realistic heating efficiencies and a radius scaling law derived from observations of hot Jupiters. We study the influence of the mean planetary density on the thermal mass loss by placing hypothetical exoplanets with the characteristics of Jup…

010504 meteorology & atmospheric sciencesGas giantEvolutionAstrophysics01 natural sciencesArticleOriginPlanet0103 physical sciencesHot JupiterAstrophysics::Solar and Stellar AstrophysicsHot NeptuneKepler-10b010303 astronomy & astrophysics0105 earth and related environmental sciencesPhysicsExoplanetsAstronomyAstronomy and AstrophysicsExoplanetCoRoT-7b13. Climate actionSpace and Planetary ScienceAstrophysics::Earth and Planetary AstrophysicsMass lossPlanetary massJupiter massIce giantPlanetary and Space Science
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Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications

2020

Boron neutron capture therapy (BNCT) is a radiotherapeutic modality based on the nuclear capture of slow neutrons by stable 10B atoms followed by charged particle emission that inducing extensive damage on a very localized level (&lt

Boron CompoundsBiodistributionboron compound[SDV.BIO]Life Sciences [q-bio]/BiotechnologyFluorophorein ovo modelAstrophysics::High Energy Astrophysical Phenomena[SDV]Life Sciences [q-bio]theranosticNuclear TheoryPhysics::Medical Physicsaza-BODIPY[SDV.CAN]Life Sciences [q-bio]/CancerBoron Neutron Capture Therapy010402 general chemistry01 natural sciencesSodium BorocaptateArticle03 medical and health scienceschemistry.chemical_compoundoptical imagingNIR-IMice0302 clinical medicine[SDV.CAN] Life Sciences [q-bio]/CancerPhysics::Atomic and Molecular ClustersAnimalsHumansNeutronNuclear Experiment10 B-BSHlcsh:QH301-705.5<sup>10</sup>B-BSHChemistryRadiochemistry10B-BSHGeneral MedicineFluorescence[SDV.BIO] Life Sciences [q-bio]/Biotechnology0104 chemical sciencesSWIR[SDV] Life Sciences [q-bio]Neutron capturelcsh:Biology (General)030220 oncology & carcinogenesisBNCTFemaleBODIPYEx vivoCells
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Biochemical and chemical characterization of Cynara cardunculus L. extract and its potential use as co-adjuvant therapy of chronic myeloid leukemia

2017

Abstract Ethnopharmacological relevance Ancient mediterranean diet was characterized by consuming the spontaneous forms of Cynara cardunculus L. (CCL), commonly called artichoke. Cultivated and/or spontaneous forms of CC studies have demonstrated that methanol extract of CCL flower and/or cynaropicrin showed remarkable anti-proliferative activity in vitro models of leukocyte cancer cell. Aim of the study Chronic myeloid leukemia (CML) is associated with a reciprocal translocation of the long arms of chromosomes 9 and 22 generating the BCR/ABL fusion gene, translated in the p210 BCR/ABL oncoprotein kinase. This chimeric protein is the target of a kinase inhibitor, imatinib, but the developme…

Cynara cardunculus L.Sesquiterpene0301 basic medicineSettore MED/06 - Oncologia MedicaFusion Proteins bcr-ablPharmacologyAntineoplastic AgentLactoneschemistry.chemical_compound0302 clinical medicinehemic and lymphatic diseasesDrug DiscoveryK562 cellABLChemistryChronic myeloid leukemiabreakpoint cluster regionMyeloid leukemiaLactoneCynaropicrinImatinib resistantChemotherapy Adjuvant030220 oncology & carcinogenesisImatinib MesylateChronic myeloid leukemia; Cynara cardunculus L.; Imatinib resistant; K562 cells; P210BCR/ABLoncoprotein; Antineoplastic Agents; Antineoplastic Agents Phytogenic; Cell Survival; Chemotherapy Adjuvant; Cynara; Drug Resistance Neoplasm; Fusion Proteins bcr-abl; Humans; Imatinib Mesylate; K562 Cells; Lactones; Leukemia Myelogenous Chronic BCR-ABL Positive; Plant Extracts; Sesquiterpenes; Pharmacology; Drug Discovery3003 Pharmaceutical ScienceSesquiterpenesHumanmedicine.drugCell SurvivalAntineoplastic AgentsCynaraPlant Extract03 medical and health sciencesLeukemia Myelogenous Chronic BCR-ABL PositivemedicineHumansViability assayneoplasmsPharmacologyPlant ExtractsCell growthDrug Discovery3003 Pharmaceutical ScienceImatinibAntineoplastic Agents PhytogenicP210BCR/ABLoncoprotein030104 developmental biologyDrug Resistance NeoplasmCancer researchK562 CellsK562 cellsJournal of Ethnopharmacology
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CCDC 1405449: Experimental Crystal Structure Determination

2015

Related Article: Saoussen Haddad, Sarra Boudriga, François Porzio, Armand Soldera, Moheddine Askri, Michael Knorr, Yoann Rousselin, Marek M. Kubicki, Christopher Golz, and Carsten Strohmann|2015|J.Org.Chem.|80|9064|doi:10.1021/acs.joc.5b01399

Space GroupCrystallography1'2'3'8'9'10'10a'10b'-octahydro-2H2''H-dispiro[acenaphthylene-15'-dipyrrolo[12-a:2'1'-c]pyrazine-6'1''-acenaphthylene]-22''-dioneCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates
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CCDC 1973338: Experimental Crystal Structure Determination

2020

Related Article: Imre Pápai, Petri M. Pihko, Juha H. Siitonen, Dániel Csókás|2020|Synlett|31|1581|doi:10.1055/s-0040-1707201

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(1R3aS10aR10bS)-1-methyloctahydro-2H-furo[32-c]pyrrolo[12-a]azepine-28(1H)-dioneExperimental 3D Coordinates
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CCDC 795379: Experimental Crystal Structure Determination

2011

Related Article: J.Barjau, G.Schnakenburg, S.R.Waldvogel|2011|Angew.Chem.,Int.Ed.|50|1415|doi:10.1002/anie.201006637

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters(5aRS10bRS4aRS15bRS)-13-Dimethoxy-56-dioxa-79121415b17-hexamethyl-(benzo[k]benzo[h]-(benzo[b]furo)[23-b]-[4.3.3]propellan)-16-eneExperimental 3D Coordinates
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CCDC 235066: Experimental Crystal Structure Determination

2005

Related Article: G.Stajer, F.Miklos, I.Kanizsai, F.Csende, R.Sillanpaa, P.Sohar|2004|Eur.J.Org.Chem.|2004|3701|doi:10.1002/ejoc.200400247

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters10b-p-tolyl-6a7891010a-hexahydro-2H-[13]oxazino[23-a]isoindol-6(6aH)-oneExperimental 3D Coordinates
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CCDC 606000: Experimental Crystal Structure Determination

2006

Related Article: E.Kaasalainen, J.Tois, L.Russo, K.Rissanen, J.Helaja|2006|Tetrahedron Lett.|47|5669|doi:10.1016/j.tetlet.2006.06.014

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters6a-Methyl-2-methoxy-8-phenyl-566a6b9a1010a10b1112-decahydropentaleno(21-a)phenanthren-7(4bH)-oneExperimental 3D Coordinates
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CCDC 209078: Experimental Crystal Structure Determination

2004

Related Article: F.Miklos, I.Kanizsai, S.Thomas, E.Kleinpeter, R.Sillanpaa, G.Stajer|2004|Heterocycles|63|63|doi:10.3987/COM-03-9916

Space GroupCrystallographyCrystal SystemCrystal StructureCell Parameters710-epoxy-10b-p-tolyl-236a7891010a-octahydro[13]oxazino[23-a]isoindol-6-oneExperimental 3D Coordinates
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CCDC 1564490: Experimental Crystal Structure Determination

2017

Related Article: Fernando Rabasa-Alcañiz, Javier Torres, María Sánchez-Roselló, Tomás Tejero, Pedro Merino, Santos Fustero, Carlos del Pozo|2017|Adv.Synth.Catal.|359|3752|doi:10.1002/adsc.201700975

Space GroupCrystallographyCrystal SystemCrystal StructureCell ParametersExperimental 3D Coordinates3-methyl-5-(nitromethyl)-10b-(trifluoromethyl)-133a4510b-hexahydro-8H-[13]dioxolo[67]naphtho[21-c][12]oxazole
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