Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications

6533b7d8fe1ef96bd126adb4

RESEARCH PRODUCT

Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications

Lucie Sancey Mans Broekgaarden Benoit Busser Jean-luc Coll Jacques Pliquett Ghadir Kalot Ewen Bodio Vincent Motto-ros Amélie Godard Christine Goze Karl David Wegner Ulli Köster Ute Resch-genger Franck Denat

subject

Boron Compounds Biodistribution boron compound [SDV.BIO]Life Sciences [q-bio]/Biotechnology Fluorophore in ovo model Astrophysics::High Energy Astrophysical Phenomena [SDV]Life Sciences [q-bio]theranostic Nuclear Theory Physics::Medical Physics aza-BODIPY [SDV.CAN]Life Sciences [q-bio]/Cancer Boron Neutron Capture Therapy 010402 general chemistry 01 natural sciences Sodium Borocaptate Article 03 medical and health sciences chemistry.chemical_compound optical imaging NIR-I Mice 0302 clinical medicine [SDV.CAN] Life Sciences [q-bio]/Cancer Physics::Atomic and Molecular Clusters Animals Humans Neutron Nuclear Experiment 10 B-BSH lcsh:QH301-705.5 <sup>10</sup>B-BSH Chemistry Radiochemistry 10B-BSH General Medicine Fluorescence [SDV.BIO] Life Sciences [q-bio]/Biotechnology 0104 chemical sciences SWIR [SDV] Life Sciences [q-bio]Neutron capture lcsh:Biology (General)030220 oncology & carcinogenesis BNCT Female BODIPY Ex vivo

description

Boron neutron capture therapy (BNCT) is a radiotherapeutic modality based on the nuclear capture of slow neutrons by stable 10B atoms followed by charged particle emission that inducing extensive damage on a very localized level (&lt

year	journal	country	edition	language
2020-08-25	Cells

10.3390/cells9091953 http://europepmc.org/articles/PMC7565158

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