0000000000324215

AUTHOR

Ghadir Kalot

0000-0002-5124-9370

showing 2 related works from this author

Aza-BODIPY: A New Vector for Enhanced Theranostic Boron Neutron Capture Therapy Applications

2020

Boron neutron capture therapy (BNCT) is a radiotherapeutic modality based on the nuclear capture of slow neutrons by stable 10B atoms followed by charged particle emission that inducing extensive damage on a very localized level (&lt

Boron CompoundsBiodistributionboron compound[SDV.BIO]Life Sciences [q-bio]/BiotechnologyFluorophorein ovo modelAstrophysics::High Energy Astrophysical Phenomena[SDV]Life Sciences [q-bio]theranosticNuclear TheoryPhysics::Medical Physicsaza-BODIPY[SDV.CAN]Life Sciences [q-bio]/CancerBoron Neutron Capture Therapy010402 general chemistry01 natural sciencesSodium BorocaptateArticle03 medical and health scienceschemistry.chemical_compoundoptical imagingNIR-IMice0302 clinical medicine[SDV.CAN] Life Sciences [q-bio]/CancerPhysics::Atomic and Molecular ClustersAnimalsHumansNeutronNuclear Experiment10 B-BSHlcsh:QH301-705.5<sup>10</sup>B-BSHChemistryRadiochemistry10B-BSHGeneral MedicineFluorescence[SDV.BIO] Life Sciences [q-bio]/Biotechnology0104 chemical sciencesSWIR[SDV] Life Sciences [q-bio]Neutron capturelcsh:Biology (General)030220 oncology & carcinogenesisBNCTFemaleBODIPYEx vivoCells
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Water-Soluble Aza-BODIPYs: Biocompatible Organic Dyes for High Contrast In Vivo NIR-II Imaging

2020

International audience; A simple NIR-II emitting water-soluble system has been developed and applied in vitro and in vivo. In vitro, the fluorophore quickly accumulated in 2D and 3D cell cultures and rapidly reached the tumor in rodents, showing high NIR-II contrast for up to 1 week. This very efficient probe possesses all the qualities necessary for translation to the clinic as well as for the development of NIR-II emitting materials.

Fluorophore[SDV]Life Sciences [q-bio]Biomedical EngineeringPharmaceutical ScienceBioengineering02 engineering and technology01 natural scienceschemistry.chemical_compoundIn vivoneoplasmsPharmacology[SDV.IB] Life Sciences [q-bio]/BioengineeringHigh contrast010405 organic chemistryOrganic Chemistrytechnology industry and agriculture021001 nanoscience & nanotechnologyBiocompatible materialequipment and suppliesFluorescenceIn vitro3. Good health0104 chemical sciences[SDV] Life Sciences [q-bio]Water solublesurgical procedures operativechemistryBiophysics[SDV.IB]Life Sciences [q-bio]/Bioengineering0210 nano-technologyPreclinical imagingBiotechnology
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