Search results for "1103"

showing 10 items of 538 documents

''Sex Differences In Ultra-triathlon Performance At Increasing Race Distance''

2013

Ruest, Christoph Alexander | Knechtle, Beat | Knechtle, Patrizia | Rosemann, Thomas | Lepers, Romuald; International audience; ''It has been argued that women should be able to outrun men in ultra-endurance distances. The present study investigated the sex difference in overall race times and split times between elite female and male Ironman triathletes competing in Ironman Hawaii (3.8 km swimming, 180 km cycling, and 42.195 km running) and Double Iron ultra-triathletes (7.6 km swimming, 360 km cycling, and 84.4 km running). Data from 20,638 athletes, including 5,163 women and 15,475 men competing in Ironman Hawaii and from 143 women and 1,252 men competing in Double Iron ultra-triathlon ra…

Male11035 Institute of General PracticeTOTAL-BODY WATERExperimental and Cognitive Psychology610 Medicine & healthSWIMMERSEXERCISE030204 cardiovascular system & hematologyAthletic PerformanceMuscle massRunningSWIMMERS''03 medical and health sciencesRace (biology)2809 Sensory Systems0302 clinical medicineSex FactorsPEAK PERFORMANCEHumansMUSCLE MASSSwimmingGENDER-DIFFERENCESbiologyAthletes3205 Experimental and Cognitive Psychology''TOTAL-BODY WATER[SCCO.NEUR]Cognitive science/NeuroscienceVO2 maxWOMEN030229 sport sciencesAnthropometrybiology.organism_classificationSkeletal muscle massSensory SystemsBicycling[ SCCO.NEUR ] Cognitive science/NeuroscienceRUNNERSPhysical EnduranceFemaleOUTRUN MENRUNNING PERFORMANCECyclingDemography
researchProduct

Global, regional, and national burden of stroke and its risk factors, 1990–2019 : a systematic analysis for the Global Burden of Disease Study 2019

2021

Background Regularly updated data on stroke and its pathological types, including data on their incidence, prevalence, mortality, disability, risk factors, and epidemiological trends, are important for evidence-based stroke care planning and resource allocation. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) aims to provide a standardised and comprehensive measurement of these metrics at global, regional, and national levels. Methods We applied GBD 2019 analytical tools to calculate stroke incidence, prevalence, mortality, disability-adjusted life-years (DALYs), and the population attributable fraction (PAF) of DALYs (with corresponding 95% uncertainty intervals [UIs]…

MaleAging030204 cardiovascular system & hematologyStroke dataGUIDELINES3124 Neurology and psychiatryBody Mass IndexGlobal Burden of Disease0302 clinical medicineRA0421Risk FactorsEpidemiologyStrokesYOUNG-ADULTSPrevalence80 and overAetiology610 Medicine & healthStrokePOPULATION1103 Clinical Sciences 1109 NeurosciencesCause of deathAged 80 and overeducation.field_of_studyMortality rateIncidence (epidemiology)Incidence1. No povertyArticlesHälsovetenskaperMiddle AgedStroke typesddc:3. Good healthStrokeISCHEMIC-STROKEIncomeFemaleQuality-Adjusted Life YearsLife Sciences & BiomedicineAdultmedicine.medical_specialtyGBDPopulationClinical SciencesClinical Neurology610 Medicine & health03 medical and health sciencesClinical ResearchMIDDLE-INCOME COUNTRIESHealth SciencesmedicineHumansRisk factoreducationGBD 2019 Stroke CollaboratorsCerebral HemorrhageAgedIschemic StrokeGlobal burdenScience & TechnologyNeurology & NeurosurgeryHYPERTENSIONbusiness.industryMORTALITYPrevention3112 NeurosciencesNeurosciences1103 Clinical SciencesSERVICESSubarachnoid Hemorrhagemedicine.diseasePREVENTIONBrain DisordersGood Health and Well BeingAttributable riskHuman medicineNeurology (clinical)Neurosciences & Neurologybusiness1109 Neurosciences030217 neurology & neurosurgeryDemography2.4 Surveillance and distributionRC
researchProduct

Effects of alirocumab on types of myocardial infarction : insights from the ODYSSEY OUTCOMES trial

2019

Gislason, Gunnar H/0000-0002-0548-402X; Malynovsky, Yaroslav V/0000-0002-9118-1104; Bhatt, Deepak L./0000-0002-1278-6245; Nikolaev, Konstantin/0000-0003-4601-6203; Sherwood, Matthew/0000-0002-4305-5883; Chumakova, Galina A/0000-0002-2810-6531; Raffel, Owen C/0000-0001-5470-7050; Leonardi, Sergio/0000-0002-4800-6132; Tse, Hung Fat/0000-0002-9578-7808; Reshetko, Olga/0000-0003-3107-7636; Pereira, Helder/0000-0001-8656-4883; Racca, Vittorio/0000-0002-4465-3789; Podoleanu, Cristian/0000-0001-9987-2519; Ersanli, Murat/0000-0003-1847-3087; Muenzel, Thomas/0000-0001-5503-4150; Sandhu, Manjinder/0000-0003-2538-2079; Taskinen, Marja-Riitta/0000-0002-6229-3588; bastos, jose/0000-0002-9526-3123; Manak…

MaleBIOMEDICINE AND HEALTHCARE. Clinical Medical Sciences.Cardiac & Cardiovascular SystemsMyocardial InfarctionUNIVERSAL DEFINITION030204 cardiovascular system & hematologyTHERAPYDISEASEchemistry.chemical_compound0302 clinical medicineCardiac and Cardiovascular Systems030212 general & internal medicineMyocardial infarctionProspective Studies1102 Cardiorespiratory Medicine and HaematologyOxygen supplyKardiologiBIOMEDICINA I ZDRAVSTVO. Kliničke medicinske znanosti.CHOLESTEROLMiddle AgedMI typesCardiologyLDL Cholesterol LipoproteinsFemaleCardiology and Cardiovascular MedicineLife Sciences & Biomedicinemedicine.medical_specialty610ODYSSEY OUTCOMES InvestigatorsAntibodies Monoclonal HumanizedCLASSIFICATION03 medical and health sciencesDouble-Blind MethodInternal medicinemedicineHumansddc:610Alirocumab ; MI types ; Mortality ; PreventionMortalityMETAANALYSISAlirocumabAgedScience & TechnologyTask forceCholesterolbusiness.industryEVOLOCUMABPrevention1103 Clinical SciencesCholesterol LDLmedicine.diseaseEvolocumabchemistryCardiovascular System & HematologyCardiovascular System & CardiologyHuman medicinebusinessAlirocumab
researchProduct

Elective Cancer Surgery in COVID-19-Free Surgical Pathways during the SARS-CoV-2 Pandemic: An International, Multicenter, Comparative Cohort Study

2020

PURPOSE As cancer surgery restarts after the first COVID-19 wave, health care providers urgently require data to determine where elective surgery is best performed. This study aimed to determine whether COVID-19–free surgical pathways were associated with lower postoperative pulmonary complication rates compared with hospitals with no defined pathway. PATIENTS AND METHODS This international, multicenter cohort study included patients who underwent elective surgery for 10 solid cancer types without preoperative suspicion of SARS-CoV-2. Participating hospitals included patients from local emergence of SARS-CoV-2 until April 19, 2020. At the time of surgery, hospitals were defined as having a …

MaleCancer ResearchOutcome AssessmentInternational CooperationSettore MED/18 - CHIRURGIA GENERALESettore MED/19 - Chirurgia Plastica030230 surgeryAged; Aged 80 and over; COVID-19; Cohort Studies; Critical Care; Elective Surgical Procedures; Epidemics; Female; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Neoplasms; Outcome Assessment Health Care; Postoperative Complications; SARS-CoV-2Cohort Studies0302 clinical medicineOperating theaterPostoperative Complicationscohort studiesNeoplasmsHealth caremiddle agedOutcome Assessment Health Care80 and overMedicineLungCancerCOVID-19/epidemiologyAged 80 and overOUTCOMESManchester Cancer Research CentrePulmonary ComplicationORIGINAL REPORTSMiddle AgedagedOncologyElective Surgical Procedures030220 oncology & carcinogenesisPneumonia & InfluenzaFemalePatient SafetyElective Surgical ProcedureLife Sciences & Biomedicine6.4 SurgeryCohort studyHumanmedicine.medical_specialtyelective surgical procedures/methodsLogistic ModelCritical CareAged; Aged; 80 and over; COVID-19; Cohort Studies; Critical Care; Elective Surgical Procedures; Epidemics; Female; Humans; International Cooperation; Logistic Models; Male; Middle Aged; Neoplasms; Outcome Assessment; Health Care; Postoperative Complications; SARS-CoV-2Clinical SciencesOncology and CarcinogenesisEpidemic[SDV.CAN]Life Sciences [q-bio]/Cancer-.cancer surgery ; COVID-19 ; SARS-CoV-2 pandemicepidemicsCOVIDSurg CollaborativeNOoutcome assessment health care/methods03 medical and health sciencesmaleSettore MED/28 - Malattie OdontostomatologicheClinical ResearchHumans1112 Oncology and CarcinogenesisOncology & CarcinogenesisElective surgeryEpidemicsElective Cancer Surgery in SARS-CoV-2 Elective Cancer Surgery in COVID-19 covid 19 sars-cov-2AgedScience & TechnologyElective Surgical Procedurebusiness.industrySARS-CoV-2PreventionResearchInstitutes_Networks_Beacons/mcrcEvaluation of treatments and therapeutic interventionsCOVID-191103 Clinical SciencesPneumoniaOdds ratiomedicine.diseaseHealth CarePneumoniaGood Health and Well Beingneoplasms/surgeryLogistic Modelscritical care/methodsEmergency medicinepostoperative complications/prevention & controlNeoplasmPostoperative ComplicationCohort Studiebusinessaged 80 and overSARS-CoV-2/physiologylogistic models
researchProduct

Global, regional, and national burden of stroke, 1990-2016

2019

Background: Stroke is a leading cause of mortality and disability worldwide and the economic costs of treatment and post-stroke care are substantial. The Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) provides a systematic, comparable method of quantifying health loss by disease, age, sex, year, and location to provide information to health systems and policy makers on more than 300 causes of disease and injury, including stroke. The results presented here are the estimates of burden due to overall stroke and ischaemic and haemorrhagic stroke from GBD 2016. Methods: We report estimates and corresponding uncertainty intervals (UIs), from 1990 to 2016, for incidence, preval…

MaleCost effectivenessIMPACTGlobal HealthGUIDELINES3124 Neurology and psychiatryBrain IschemiaGlobal Burden of DiseaseCOST-EFFECTIVENESS0302 clinical medicineRisk FactorsGlobal healthPrevalenceMedicine030212 general & internal medicineStrokePOPULATIONAged 80 and overRISKeducation.field_of_studyIncidence (epidemiology)Mortality rateIncidenceAge FactorsMiddle AgedPREVALENCEStrokeFemaleLife Sciences & BiomedicineIntracranial HemorrhagesAdultPopulationClinical Neurology03 medical and health sciencesHumanseducationAgedScience & TechnologyNeurology & Neurosurgerybusiness.industry3112 NeurosciencesKlinisk medicin1103 Clinical Sciencesmedicine.diseaseGBD 2016 Stroke CollaboratorsVerbal autopsyTRANSIENT ISCHEMIC ATTACKYears of potential life lostSocioeconomic FactorsHuman medicineNeurosciences & NeurologyNeurology (clinical)Clinical Medicine1109 NeurosciencesbusinessPRIMARY PREVENTION030217 neurology & neurosurgeryDemographyRCLancet Neurology
researchProduct

Unexplained chronic liver disease in Ethiopia: a cross-sectional study

2018

Background Hepatitis B virus (HBV) infection is assumed to be the major cause of chronic liver disease (CLD) in sub-Saharan Africa. The contribution of other aetiological causes of CLD is less well documented and hence opportunities to modulate other potential risk factors are being lost. The aims of this study were to explore the aetiological spectrum of CLD in eastern Ethiopia and to identify plausible underlying risk factors for its development. Methods A cross-sectional study was undertaken between April 2015 and April 2016 in two public hospitals in Harar, eastern Ethiopia. The study population comprised of consenting adults with clinical and radiological evidence of chronic liver dise…

MaleCross-sectional studyEpidemiologyBiopsyChronic liver disease0302 clinical medicineRisk FactorsKhatEpidemiologyPrevalenceSIMPLE NONINVASIVE INDEX030212 general & internal medicineViral hepatitisPOPULATIONbiologymedicine.diagnostic_testSub-Saharan AfricaLiver DiseasesGastroenterologyCHRONIC HEPATITISGeneral MedicineAlcoholismLiverLiver biopsyPopulation studyFemale030211 gastroenterology & hepatologyC HEPATITISViral hepatitisLife Sciences & BiomedicineResearch ArticleAdultmedicine.medical_specialtySubstance-Related DisordersAcute Lung InjuryKHAT LEAVESAUTOIMMUNEVERBAL AUTOPSY METHODCathaVIRUS-INFECTIONCatha edulis03 medical and health sciencesInternal medicinemedicineHumanslcsh:RC799-869Science & TechnologyGastroenterology & HepatologySIGNIFICANT FIBROSISbusiness.industryHepatotoxicity1103 Clinical SciencesHepatologybiology.organism_classificationmedicine.diseaseCross-Sectional StudiesChronic Diseaselcsh:Diseases of the digestive system. GastroenterologyEthiopiabusiness
researchProduct

Women Outperform Men in Ultra-Distance Swimming - The 'Manhattan Island Marathon Swim' From 1983 to 2013

2014

Purpose:Recent studies suggested that women’s and men’s ultraswim performances may be similar for distances of ~35 km. The current study investigated both the gender difference and the age of peak ultraswim performance between 1983 and 2013 at the 46-km Manhattan Island Marathon Swim with water temperatures <20°C.Methods:Changes in race times and gender difference in 551 male and 237 female finishers were investigated using linear-, nonlinear-, and hierarchical multilevel-regression analyses.Results:The top 10 race times ever were significantly (P < .0001) lower for women (371 ± 11 min) than for men (424 ± 9 min). Race times of the annual fastest and annual 3 fastest women and men did…

MaleGerontology11035 Institute of General PracticeCompetitive BehaviorNew YorkEnergy metabolismPhysical Therapy Sports Therapy and Rehabilitation610 Medicine & healthSex Factors2732 Orthopedics and Sports MedicineSex factorsHumansMedicineOrthopedics and Sports Medicine3612 Physical Therapy Sports Therapy and RehabilitationSwimmingAdipositybusiness.industryAge FactorsCold TemperaturePhysical EnduranceRegression AnalysisFemaleEnergy MetabolismbusinessDemography
researchProduct

Age, training, and previous experience predict race performance in long-distance inline skaters, not anthropometry

2012

Knechtle, Beat | Knechtle, Patrizia | Ruest, Christoph Alexander | Rosemann, Thomas | Lepers, Romuald; International audience; ''The association of characteristics of anthropometry, training, and previous experience with race time in 84 recreational, long-distance, inline skaters at the longest inline marathon in Europe (111 km), the Inline One-eleven in Switzerland, was investigated to identify predictor variables for performance. Age, duration per training unit, and personal best time were the only three variables related to race time in a multiple regression, while none of the 16 anthropometric variables were related. Anthropometric characteristics seem to be of no importance for a fast …

MaleGerontologyFuture studiesSWIMMING PERFORMANCEInline skating030204 cardiovascular system & hematologyRace (biology)0302 clinical medicineTRIATHLON PERFORMANCESMARATHON RUNNERSMENTAL TOUGHNESSPhysical Education and TrainingAnthropometrybiologyAge FactorsContrast (statistics)Middle AgedSensory SystemsTIMESkinfold Thickness[ SCCO.NEUR ] Cognitive science/Neurosciencesports.sport''SKIN-FOLD THICKNESSESPsychologyAdult11035 Institute of General PracticeBODY-COMPOSITIONsportsAccelerationExperimental and Cognitive Psychology610 Medicine & healthAthletic Performance03 medical and health sciences2809 Sensory SystemsHumansAssociation (psychology)ULTRA-MARATHONERSTIME''Athletes3205 Experimental and Cognitive Psychology[SCCO.NEUR]Cognitive science/NeuroscienceTraining (meteorology)030229 sport sciencesAnthropometrybiology.organism_classificationSKIN-FOLD THICKNESSESPractice PsychologicalSkatingPhysical EnduranceUPPER ARMRUNNING PERFORMANCE
researchProduct

Prevalence, associated factors and outcomes of pressure injuries in adult intensive care unit patients: the DecubICUs study

2020

Funder: European Society of Intensive Care Medicine; doi: http://dx.doi.org/10.13039/501100013347

MaleOriginalmedicine.medical_treatmentartificialCritical Care and Intensive Care MedicineMedical and Health SciencesPressure ulcerlaw.inventionDecubitus epidemiology; ICU; Morbidity; Mortality; Outcome; Pressure injury; Pressure ulcer; Risk factors; Adult; Aged; Hospital Mortality; Humans; Male; Patient Discharge; Prevalence; Risk Factors; Intensive Care Units; Respiration Artificial0302 clinical medicineDecubitus epidemiologydecubitus epidemiology ; ICU ; pressure injury ; pressure ulcer ; outcome ; risk factors ; morbidity ; mortalitylawMedicine and Health SciencesadultsPrevalenceMedicineHospital MortalitySimplified Acute Physiology Scoredecubitus epidemiology; icu; pressure injury; pressure ulcer; outcome; risk factors; morbidityziekenhuissterfteImmunodeficiencyintensive careOutcomeEuropean Society of Intensive Care Medicine (ESICM) Trials Group CollaboratorsmannenvolwassenenCOSTIntensive care unitSTATEPatient DischargeIntensive Care UnitsULCERSUnderweightmedicine.symptomLife Sciences & BiomedicineDecubitus epidemiology; ICU; Morbidity; Mortality; Outcome; Pressure injury; Pressure ulcer; Risk factorsHumanAdultmedicine.medical_specialtyrisicofactorenDecubitus epidemiology ICU Pressure injury Pressure ulcer Outcome Risk factors Morbidity Mortalitypressure injuriesIntensive Care UnitprevalentieNO1117 Public Health and Health ServicesDecubICUs Study Team03 medical and health sciencesCritical Care MedicineAnesthesiologyGeneral & Internal MedicineHealth SciencesouderenHumansMortalityAgedMechanical ventilationScience & Technologybusiness.industrydecubitusRisk Factor030208 emergency & critical care medicine1103 Clinical SciencesOdds ratiomedicine.diseaseRespiration ArtificialEmergency & Critical Care MedicineConfidence interval030228 respiratory systemRisk factorsEmergency medicineICUkunstmatige ademhalingRISK-FACTORSMorbiditybusinessPressure injuryrespiration
researchProduct

Screening trematodes for novel intervention targets: a proteomic and immunological comparison of Schistosoma haematobium, Schistosoma bovis and Echin…

2011

SUMMARYWith the current paucity of vaccine targets for parasitic diseases, particularly those in childhood, the aim of this study was to compare protein expression and immune cross-reactivity between the trematodes Schistosoma haematobium, S. bovis and Echinostoma caproni in the hope of identifying novel intervention targets. Native adult parasite proteins were separated by 2-dimensional gel electrophoresis and identified through electrospray ionisation tandem mass spectrometry to produce a reference gel. Proteins from differential gel electrophoresis analyses of the three parasite proteomes were compared and screened against sera from hamsters infected with S. haematobium and E. caproni fo…

MaleProteomicsProteome/dk/atira/pure/subjectarea/asjc/2400/2405ProteomicstrematodeimmunologyEXPERIMENTAL-INFECTIONS. bovis0302 clinical medicineCricetinaeEchinostoma/dk/atira/pure/subjectarea/asjc/2700/2725SchistosomiasisParasite hostingElectrophoresis Gel Two-DimensionalChildDIGEGENE-EXPRESSIONGel electrophoresisSchistosoma haematobiumEchinostomiasis0303 health sciencesBiomphalaria/dk/atira/pure/subjectarea/asjc/1100/1103IMMUNE-RESPONSESEchinostosma caproniHelminth ProteinsUp-RegulationPROTEIN DISULFIDE-ISOMERASE3. Good healthPhenotypeInfectious DiseasesProteomeSchistosoma haematobiumSchistosomaEchinostomaResearch ArticleFRIEDI TREMATODABulinus030231 tropical medicineMANSONICross ReactionsBiologyHost-Parasite InteractionsMicrobiologyS. haematobium03 medical and health sciencesproteomicsSpecies SpecificityDIAAnimalsHumansFasciola hepaticaPARASITE030304 developmental biologySchistosomaFASCIOLA-HEPATICAMOLECULAR-CLONINGMesocricetusANCYLOSTOMA-CANINUMbiology.organism_classificationvaccine developmentAntigens HelminthImmunologyAnimal Science and ZoologyParasitologyParasitology
researchProduct