Search results for "124"
showing 10 items of 329 documents
Cardiorespiratory fitness measured with cardiopulmonary exercise testing and mortality in patients with cardiovascular disease: A systematic review a…
2021
Highlights • High cardiorespiratory fitness (CRF) in patients with cardiovascular disease (CVD) is associated with 58% lower all-cause mortality risk and 73% lower cardiovascular mortality risk compared to unfit counterparts. • Each 1 metabolic equivalent (1-MET) increase in CRF is associated with a 19% lower CVD mortality risk among patients with CVD. • Coronary artery disease patients with high CRF have a 68% lower all-cause mortality risk than their unfit counterparts. • Each 1-MET increase in CRF is associated with a 17% lower all-cause mortality risk among patients with coronary artery disease. • No significant associations were found between increments of 1-MET and lower mortality ris…
Auditory‐evoked potentials to changes in sound duration in urethane‐anaesthetized mice
2019
Spectrotemporally complex sounds carry important information for acoustic communication. Among the important features of these sounds is the temporal duration. An event-related potential called mismatch negativity indexes auditory change detection in humans. An analogous response (mismatch response) has been found to duration changes in speech sounds in rats but not yet in mice. We addressed whether mice show this response, and, if elicited, whether this response is functionally analogous to mismatch negativity or whether adaptation-based models suffice to explain them. Auditory-evoked potentials were epidurally recorded above the mice auditory cortex. The differential response to the chang…
[Osteoporosis and diabetes].
2011
Diabetes mellitus and osteoporosis are chronic diseases with an elevated and growing incidence in the elderly. Recent epidemiological studies have demonstrated an elevated risk of hip, humerus and foot fractures in elder diabetic subjects. While type 1 diabetes is generally associated with a mild reduction in bone mineral density (BMD), type 2 diabetes, more prevalent in old subjects, is frequently linked to a normal or high BMD. Studies on experimental models of diabetes have suggested an altered bone structure that may help to explain the elevated risk of fractures observed in these animals and may as well help to explain the paradox of an incremented risk of fractures in type 2 diabetic …
Use of antidepressants among Finnish family caregivers : a nationwide register-based study
2021
Abstract Purpose The purpose of this study was to compare the use of antidepressants over 6 years between family caregivers providing high-intensity care and a matched control population using register-based data. Methods The study includes all individuals, who received family caregiver’s allowance in Finland in 2012 (n = 29,846 females, mean age 66 years; n = 12,410 males, mean age 71 years) and a control population matched for age, sex, and municipality of residence (n = 59,141 females; n = 24,477 males). Information on purchases of antidepressants, including the number of defined daily doses (DDD) purchased, between 2012 and 2017 was obtained from the national drugs reimbursement registe…
Pan-cancer analysis of whole genomes
2020
Publisher's version (útgefin grein)
Long-Term Response to Cholinesterase Inhibitor Treatment Is Related to Functional MRI Response in Alzheimer's Disease.
2015
<b><i>Background:</i></b> Treatment of Alzheimer's disease (AD) with cholinesterase inhibitors (ChEI) enhances cholinergic activity and alleviates clinical symptoms. However, there is variation in the clinical response as well as system level changes revealed by functional MRI (fMRI) studies. <b><i>Methods:</i></b> We investigated 18 newly diagnosed mild AD patients with fMRI using a face recognition task after a single oral dose of rivastigmine, a single dose of placebo and 1-month treatment with rivastigmine. The clinical follow-up took place at 6 and 12 months. <b><i>Results:</i></b> MMSE score difference between bas…
Critical incidents which limit performance of Chilean University rowers who won a medal in the Pan American Games of Lima 2019
2020
Main objective of this study was to provide a basis for the comprehension of the main critical incidents (i.e. obstacles) that Chilean rowers who were medallists in the Pan American Games of Lima 2019 have to face within the academic, socioeconomic and sports processes. 19 athletes were selected through a non-probabilistic sampling. A content validated questionnaire and an in-deep interview were used. Higher levels of consistency were observed. Through the inferential analysis (ANOVA) it was possible to conclude that athletes are concerned with some academic and social crisis within their sporting career. This fact does not allow them to concentration and integral tranquillity to be focused…
Technical and tactical analysis of women’s volleyball
2013
Summary Introduction: The study aim was to construct a technical and tactical analysis of women’s volleyball based on notational analysis in top-level and junior women’s European volleyball matches, to compare these two levels, and to clarify the differences between the winners and losers of a set. Material and Methods: Four matches from the 2010 FIVB Women’s Volleyball World Championships and 2010 CEV Junior Women’s European Championship 2010 were analyzed using Data Volley software. The number and performance level of different skills were recorded in total and were grouped according to the role of the players. Methods of scoring and attacking zones were also analyzed. Results: There were…
Anodal tDCS over the left prefrontal cortex does not cause clinically significant changes in circulating metabolites
2020
Background: Transcranial direct current stimulation (tDCS), a putative treatment for depression, has been proposed to affect peripheral metabolism. Metabolic products from brain tissue may also cross the blood–brain barrier, reflecting the conditions in the brain. However, there are no previous data regarding the effect of tDCS on circulating metabolites.\ud Objective: To determine whether five daily sessions of tDCS modulate peripheral metabolites in healthy adult men.\ud Methods: This double-blind, randomized controlled trial involved 79 healthy males (aged 20–40 years) divided into two groups, one receiving tDCS (2 mA) and the other sham stimulated. The anode was placed over the left dor…
Gender differences in technical-tactical behaviour of La Liga Spanish football teams
2021
[Abstract] The aim of this study was to identify differences in technical-tactical behaviour between the men and women first division football teams of the Spanish league, to this end 68 matches corresponding to 2016/17 season were analysed. A comparative analysis of the medians was carried out using the Mann-Whitney U-tests were conducted as post hoc tests. The size effect of this test was calculated and, finally, we performed a grouping of the variables through the clustering bootstrapping technique in both groups. We have detected statistically significant differences (p <0.01) regarding all accurate passes, in favour of men, as well as a greater number of yellow cards. In female footbal…