Search results for "140"

showing 10 items of 140 documents

WNT2 activation through proximal germline deletion predisposes to small intestinal neuroendocrine tumors and intestinal adenocarcinomas

2021

Abstract Many hereditary cancer syndromes are associated with an increased risk of small and large intestinal adenocarcinomas. However, conditions bearing a high risk to both adenocarcinomas and neuroendocrine tumors are yet to be described. We studied a family with 16 individuals in four generations affected by a wide spectrum of intestinal tumors, including hyperplastic polyps, adenomas, small intestinal neuroendocrine tumors, and colorectal and small intestinal adenocarcinomas. To assess the genetic susceptibility and understand the novel phenotype, we utilized multiple molecular methods, including whole genome sequencing, RNA sequencing, single cell sequencing, RNA in situ hybridization…

AdenomaAcademicSubjects/SCI01140DOMAINSadenokarsinoomaCANCER-RISKIn situ hybridizationsuolistosyövätAdenocarcinomaBiologyNeuroendocrine tumorsGermlineWnt2 Proteinperinnöllinen alttius03 medical and health sciences0302 clinical medicineWNT2GeneticsGenetic predispositionmedicineHumansIntestinal MucosaMUTATIONMolecular BiologyGenetics (clinical)030304 developmental biologypaksusuolisyöpäCARCINOID-TUMORS0303 health sciencesperinnölliset tauditCYSTIC-FIBROSISGeneral MedicineNATIONWIDEmedicine.diseaseIntestinal epithelium3. Good healthGENOMENeuroendocrine TumorsHyperplastic PolypSingle cell sequencing3121 General medicine internal medicine and other clinical medicine030220 oncology & carcinogenesisMAPCancer researchsyöpätaudit3111 BiomedicineGeneral Articlegeneettiset tekijätColorectal Neoplasms
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Moving European research on work and ageing forward: Overview and agenda:

2010

This paper summarizes the state of affairs of European research on ageing and work. After a close inspection of the age construct, an overview is presented of research in four areas: the relationship between age and HR-policies, early retirement, age and performance/employability, age and health/well-being. The overview results in a research agenda on work and ageing and in recommendations for practice. © 2009 Psychology Press. ispartof: European Journal of Work and Organizational Psychology vol:19 issue:1 pages:76-101 status: published

Ageing and workEconomic growthOrganizational Behavior and Human Resource ManagementSATISFACTIONState of affairsReviewEmployability1407 Organizational Behavior and Human Resource ManagementOlder employeesHuman capitalMETIS-2683743202 Applied PsychologyCIVIL-SERVANTSBusiness economicsJOB-PERFORMANCEIR-7345210091 Institute of EducationDECISIONSEMPLOYMENTRETIREMENTSociologyATTITUDESSocial scienceWorkplace150311 Organisational BehaviourApplied PsychologySocial policyLITERATURE REVIEWGENDER-DIFFERENCESResponsible OrganizationELDER WORKERSPERFORMANCEEARLY-RETIREMENTEuropeWork (electrical)Job performanceEMPLOYABILITYOLDER WORKERSHEALTH370 EducationConstruct (philosophy)
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Le journal d'un Bourgeios de Paris : analyse philologique et historique

2000

Arc Jeanne d'Journal d'un Bourgeios de Paris1400-luku
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Rehabilitering av antikvarisk betongkonstruksjon fra perioden 1926-1938 : Vurdering av rehabiliteringstiltak og restkapasitet for Ingierstrand bad, b…

2017

Masteroppgave bygg BYG500 - Universitetet i Agder 2017 Traditionally restoration of antiquarian concrete constructions has been a prominent topic in Norwegian context. This topic has been given more attention, as more concrete constructions and reinforced concrete constructions have been preserved. In this thesis a case-study were done of Ingierstrand bad. A central part of the restoration of antiquarian concrete constructions is to control the capacity of the concrete against occurring stresses. We have in this thesis theoretically controlled the capacity of the standard being used during projecting and building, and that of today’s standard. We suggested the actions of restoration we thin…

BYG500VDP::Teknologi: 500::Bygningsfag: 530::Arkitektur og bygningsteknologi: 531VDP::Teknologi: 500::Materialteknologi: 520::Bygningsmaterialer: 525VDP::Humaniora: 000::Arkitektur og design: 140::Arkitektur- og designhistorie: 141
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Neodymium-140 DOTA-LM3: Evaluation of an In Vivo Generator for PET with a Non-Internalizing Vector

2017

140Nd (t1/2 = 3.4 days), owing to its short-lived positron emitting daughter 140Pr (t1/2 = 3.4 min), has promise as an in vivo generator for positron emission tomography (PET). However, the electron capture decay of 140Nd is chemically disruptive to macrocycle-based radiolabeling, meaning that an in vivo redistribution of the daughter 140Pr is expected before positron emission. The purpose of this study was to determine how the delayed positron from the de-labeled 140Pr affects preclinical imaging with 140Nd. To explore the effect, 140Nd was produced at CERN-ISOLDE, reacted with the somatostatin analogue, DOTA-LM3 (1,4,7,10- tetraazacyclododecane, 1,4,7- tri acetic acid, 10- acetamide N - p…

BiodistributionPositron emission tomographypositron emission tomographyElectron captureDOTA-LM3030218 nuclear medicine & medical imaging03 medical and health scienceschemistry.chemical_compound0302 clinical medicinePositronin vivo generatorIn vivomedicineDOTAPositron emissionOriginal Research140Prlcsh:R5-920medicine.diagnostic_test140Ndbusiness.industryChemistryGeneral MedicineinternalizationPositron emission tomography030220 oncology & carcinogenesisBiophysicsMedicineNuclear medicinebusinesslcsh:Medicine (General)Preclinical imagingInternalizationFrontiers in Medicine
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Factors in the global assimilation of collaborative information technologies: an exploratory investigation in five regions

2008

The diffusion of innovation theory is deployed to investigate the global assimilation of collaborative information technologies (CITs). Based on the concepts of IT acquisition and utilization, an assimilation framework is presented to highlight four states (limited, focused, lagging, and pervasive) that capture the assimilation of conferencing and groupware CITs. Data collected from 538 organizations in the United States, Australia, Hong Kong, Norway, and Switzerland are aggregated and analyzed to explore assimilation patterns and the influence of decision-making pattern, functional integration, promotion of collaboration, organization size, and IT function size on the assimilation of CITs.…

Collaborative softwareInformation Systems and ManagementKnowledge managementDiffusion of innovation theory10009 Department of Informaticsbusiness.industrymedia_common.quotation_subjectInformation technologyAssimilation (biology)1803 Management Science and Operations Research000 Computer science knowledge & systemsManagement Science and Operations ResearchComputer Science ApplicationsManagement Information Systems1404 Management Information SystemsPromotion (rank)Geography1706 Computer Science Applications1802 Information Systems and ManagementbusinessLaggingFunction (engineering)media_common
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Is participation in the tourism market an opportunity for everyone? Some evidence from Italy

2016

This paper investigates whether there are differences in tourism consumption behaviour among families by analysing the main determinants of tourism participation at national and international levels. In particular, it explores whether tourism is becoming part of the lifestyle of Italians or whether it is still a luxury good only for the privileged. A Heckman model was used on micro-data on Italian family expenditure over the period 1997–2007, and an income elasticity analysis for different personal and household characteristics was carried out. The results show that participation in the tourism market is strongly affected by the personal characteristics of individuals and that tourism cons…

Consumption (economics)Income elasticityEconomic growthTourism geography05 social sciencesGeography Planning and DevelopmentStandard of livingHurdle modelHurdle models.Tourism consumptionTourism marketTourism participationEcotourismTourism Leisure and Hospitality ManagementSettore SECS-S/03 - Statistica Economica0502 economics and businessEconomics050211 marketingDemographic economicsHeckman correction1409Income elasticity of demand050212 sport leisure & tourismTourismDomestic and international tourism
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The nature of Lambda (1405) hyperon resonance in chiral dynamics

2010

10th International Conference on Hypernuclear and Strange Particle Physics. Tokai, JAPAN, SEP 14-18, 2009

CouplingPhysicsNuclear and High Energy PhysicsParticle physicsKaon induced Lambda (1405) productionNuclear TheoryScatteringHadronSpectrum (functional analysis)HyperonStructure of Lambda (1405)FOS: Physical sciencesFísicaResonance (particle physics)Spectral lineNuclear Theory (nucl-th)K(K)over-barN quasibound stateChiral unitary modelHigh Energy Physics::ExperimentInvariant massAtomic physics
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Social transmission in the wild can reduce predation pressure on novel prey signals

2021

Funder: Suomen Kulttuurirahasto (Finnish Cultural Foundation); doi: https://doi.org/10.13039/501100003125

DYNAMICS0106 biological sciences0301 basic medicineINFORMATIONBehavioural ecologyAVOIDANCEGeneral Physics and AstronomyPREFERENCESALTERNATIVE PREYEvolutionary ecology01 natural sciencesConformityPredationlaw.inventionlaw/631/181/2481kulttuurievoluutioPasseriformesCOLORATIONcultural evolutionsinitiainenmedia_commoneducation.field_of_studyMultidisciplinarybiologyEcologyCyanistesQarticlebehavioural ecologyCONFORMITYtalitiainenBiological Evolutionsosiaalinen oppiminen/631/158/856evoluutioekologiaTransmission (mechanics)/631/158/8571181 Ecology evolutionary biologycoevolution/631/181/1403media_common.quotation_subjectSciencePopulationCultural evolutioneläinten käyttäytyminen010603 evolutionary biologyGeneral Biochemistry Genetics and Molecular Biology03 medical and health sciencesGREGARIOUSNESSAvoidance LearningJuvenileAnimalsSelection GeneticeducationEvolutionary dynamicsSocial BehaviorParusGeneral Chemistrybiology.organism_classificationBLACKBIRDSPrunus dulcisEVOLUTIONsaalistusUnited Kingdom030104 developmental biologyPredatory Behaviorevolutionary ecologyRemote Sensing TechnologyVocalization AnimalCoevolutionNature Communications
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SUP R DSS: A sustainability-based decision support & system for road pavements

2019

Road pavement community members are increasingly becoming aware of the need to incorporating the principles of sustainable development into the sector. Policies are also going in this direction and as a consequence in the recent years researchers and practitioners are coming up with new materials, technologies and practices designed to reduce the negative impacts of their activities in the surroundings. Within this framework the road pavements sector is witnessing a paradigm shift towards the development of pavement technologies incorporating high-content of recycled materials, as well as best practices to decrease the overall carbon footprint. These are all promising solutions that to the …

Decision support systemCHAUSSEEComputer science020209 energyStrategy and ManagementStrategy and Management1409 TourismContext (language use)02 engineering and technologyIndustrial and Manufacturing Engineering12. Responsible consumptionTransport engineeringLife cycle thinking; Multi-criteria decision analysis; Sustainability assessment; Sustainable design; Sustainable engineering; Sustainable pavements; Renewable Energy Sustainability and the Environment; 2300; Strategy and Management1409 Tourism Leisure and Hospitality Management; Industrial and Manufacturing Engineering[SPI]Engineering Sciences [physics]11. Sustainability0202 electrical engineering electronic engineering information engineeringSustainable designSettore ICAR/04 - Strade Ferrovie Ed AeroportiSustainable engineeringRenewable EnergySUSTAINABILITY ASSESSMENT0505 lawGeneral Environmental ScienceSustainable developmentSUSTAINABLE DESIGNSustainability and the Environment2300Renewable Energy Sustainability and the EnvironmentSustainability assessment Sustainable pavements Sustainable design Sustainable engineering Life cycle thinking Multi-criteria decision analysisLeisure and Hospitality Management05 social sciencesMULTI-CRITERIA DECISION ANALYSISMultiple-criteria decision analysisSUSTAINABLE ENGINEERING13. Climate actionSustainability050501 criminologyMATERIAU RECYCLEDEVELOPPEMENT DURABLESUSTAINABLE PAVEMENTSLIFE CYCLE THINKINGDecision analysis
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