Search results for "17"
showing 10 items of 14048 documents
CORTE DI CASSAZIONE; sezione III penale; sentenza 23 maggio - 14 novembre 2013, n. 45468; Pres. LOMBARDI, Est. Grillo, PM Lettieri (concl. diff.); ri…
2014
Nota di richiami alla pronuncia CORTE DI CASSAZIONE; sezione III penale; sentenza 23 maggio - 14 novembre 2013, n. 45468; Pres. LOMBARDI, Est. Grillo, PM Lettieri (concl. diff.); ric. U., ove annullando parzialmente App. Roma 25 maggio 2012, si afferma che la ricerca di un contatto con lo stalker da parte della vittima del reato di atti persecutori, non contrastando col concetto di stress enunciato dalla norma incriminatrice, non esclude la configurabilità del delitto di cui all’art. 612 bis c.p.; tuttavia, nelle ipotesi di reciprocità dei comportamenti molesti, incombe sul giudice un più accurato onere di motivazione in ordine alla sussistenza dello stato d’ansia o di paura della persona o…
Olof Schalberg : akateeminen perintö ja teoreettisen filosofian rappiotila
2022
”Springer som en warg för att röfwa och plundra människior” : förseelser inom de östfinska lokala myndigheternas tjänsteutövning 1770–1829
2022
Korruptio ja huono hallinto tutkimuskohteena varhaismodernissa Ruotsissa : näkökulmat, menetelmät ja mahdollisuudet
2021
Artikkelissa käsitellään korruption ja huonon hallinnon tutkimusta menneisyydessä, ennen kaikkea Ruotsin ja Suomen yhteisen historian ajalla. Tarkoituksena on antaa tämänhetkisen tutkimustiedon valossa yleiskuva siitä, mitä teemasta tällä hetkellä tiedetään sekä pohtia tulevan tutkimuksen mahdollisuuksia, ongelmia (mukaan luettuna lähdekriittiset vaikeudet) sekä vastaisen tutkimuksen lähestymistapoja.
Övervakning av försummelse och korruption i häradshövdingars tjänsteutövning i Viborgs guvernement 1750-1780-talen
2022
Advokatfiskalerna vid hovrätterna i Finland fram till 1900 : utbildning, karriär och social status
2022
Purification and crystallization of the two major coat proteins of bacteriophage P23-77 for x-ray crystallography
2009
Lipid Binding Controls Dimerization of the Coat Protein p24 Transmembrane Helix
2019
Abstract Coat protein (COP) I and COP II complexes are involved in the transport of proteins between the endoplasmic reticulum and the Golgi apparatus in eukaryotic cells. The formation of COP I/II complexes at membrane surfaces is an early step in vesicle formation and is mastered by p24, a type I transmembrane protein. Oligomerization of p24 monomers was suggested to be mediated and/or stabilized via interactions within the transmembrane domain, and the p24 transmembrane helix appears to selectively bind a single sphingomyelin C18:0 molecule. Furthermore, a potential cholesterol-binding sequence has also been predicted in the p24 transmembrane domain. Thus, sphingomyelin and/or cholestero…
PTC124-mediated translational readthrough of a nonsense mutation causing Usher syndrome type 1C.
2011
We investigated the therapeutic potential of the premature termination codon (PTC) readthrough-inducing drug PTC124 in treating the retinal phenotype of Usher syndrome, caused by a nonsense mutation in the USH1C gene. Applications in cell culture, organotypic retina cultures, and mice in vivo revealed significant readthrough and the recovery of protein function. In comparison with other readthrough drugs, namely the clinically approved readthrough-inducing aminoglycoside gentamicin, PTC124 exhibits significant better retinal biocompatibility. Its high readthrough efficiency in combination with excellent biocompatibility makes PTC124 a promising therapeutic agent for PTCs in USH1C, as well a…
Visual Contrast Modulates Operant Learning Responses in Larval Zebrafish.
2018
The larval zebrafish is a promising vertebrate model organism to study neural mechanisms underlying learning and memory due to its small brain and rich behavioral repertoire. Here, we report on a high-throughput operant conditioning system for zebrafish larvae, which can simultaneously train 12 fish to associate a visual conditioned pattern with electroshocks. We find that the learning responses can be enhanced by the visual contrast, not the spatial features of the conditioned patterns, highlighted by several behavioral metrics. By further characterizing the learning curves as well as memory extinction, we demonstrate that the percentage of learners and the memory length increase as the co…