Search results for "2 diabetes"

New developments in the pathogenesis of obesity-induced hypertension

2015

Obesity is a disorder that develops from the interaction between genotype and environment involving social, behavioral, cultural, and physiological factors. Obesity increases the risk for type 2 diabetes mellitus, hypertension, cardiovascular disease, cancer, musculoskeletal disorders, chronic kidney and pulmonary disease. Although obesity is clearly associated with an increased prevalence of hypertension, many obese individuals may not develop hypertension. Protecting factors may exist and it is important to understand why obesity is not always related to hypertension. The aim of this review is to highlight the knowledge gap for the association between obesity, hypertension, and potential …

Intermittent Fasting and the Possible Benefits in Obesity, Diabetes, and Multiple Sclerosis: A Systematic Review of Randomized Clinical Trials

2021

Intermittent fasting has become popular in recent years and is controversially presented as a possible therapeutic adjunct. A bibliographic review of the literature on intermittent fasting and obesity, diabetes, and multiple sclerosis was carried out. The scientific quality of the methodology and the results obtained were evaluated in pairs. Intermittent fasting has beneficial effects on the lipid profile, and it is associated with weight loss and a modification of the distribution of abdominal fat in people with obesity and type 2 diabetes as well as an improvement in the control of glycemic levels. In patients with multiple sclerosis, the data available are too scarce to draw any firm con…

Melatonin Concentrations and Sleep Quality in Patients with Type 2 Diabetes and Obesity

2019

Abstract There is a close relationship between melatonin as a circadian regulator and insulin, glucagon and somatostatin production. This study aimed to describe subgroups of type 2 diabetes mellitus (T2DM) patients that may benefit from melatonin clock-targeting properties. The study involved 38 participants: 26 T2DM patients, and 12 participants without diabetes in the control group. Subjects were asked to complete the questionnaire of Pittsburgh Sleep Quality Index (PSQI). Standard biochemical venous sample testing was performed, and a sample of saliva was collected for melatonin testing. Melatonin concentration in participants without obesity (body mass index (BMI) < 30 kg/m2) was si…

Obesity and diabetes-Not only a simple link between two epidemics

2018

Summary Diabetes (DM) as well as obesity, due to their increasing incidence, were recognized as epidemic by the World Health Organization. Obesity is involved not only in the aetiopathogenesis of the most common worldwide type of DM—type 2 diabetes—but also in the development of its complications. There is also increasing scientific evidence regarding the role of obesity and overweight in type 1 diabetes. Weight gain may be considered as a complication of insulin treatment but also reveals significant pathophysiological impact on various stages of the disease. Another very important aspect related to DM as well as obesity is the microbiome, which is highly variable. The function of the gut …

Should we measure routinely oxidized and small dense low-density lipoproteins in subjects with type 2 diabetes

2010

Leisure‐time cross‐country skiing is associated with lower incidence of type 2 diabetes : A prospective cohort study

2020

Aims. Cross‐country skiing is associated with reduction in risk of adverse vascular outcomes, but its association with type 2 diabetes is uncertain. We aimed to assess the associations between leisure‐time cross‐country skiing habits and incident type 2 diabetes. Methods. We analyzed data of 2,483 middle‐aged men with no history of diabetes at baseline in the KIHD prospective study. The frequency, average duration, and intensity of leisure cross‐country skiing were assessed at baseline using a 12‐month physical activity questionnaire. Hazard ratios (HRs) (95% CIs) for type 2 diabetes were estimated. Results. During a median follow‐up of 21.6 years, 539 men developed type 2 diabetes. Type 2 …

Conséquences d'un régime diabétogène enrichi en fructose sur la muqueuse olfactive : aspects anatomiques, fonctionnels et comportementaux

2015

The influence of metabolic status on olfactory processes has been thoroughly investigated over the last few years. Both nutritional status and hormones implicated in food metabolism can effectively modulate the olfactory system from the single neuron to the behavior. Thus, it seems likely that metabolic disorders such as type 2 diabetes (T2D) can induce olfactory dysfunctions. In fact T2D patients display poor olfactory performances however the effects of diabetes in itself (as well as underlying mechanisms) are still unknown. In this study, we investigated the modulation of olfaction in young adult male mice caused by a high-fructose diet (HFruD) inducing T2D in rodents. Animals displayed …

Comparative analysis of socioeconomic, behavioral and biological factors between healthy patients and patients with newly diagnosed diabetes in the L…

2020

Introduction. The most effective way to prevent a dramatic increase in the number of diabetic patients lies in early detection of its risk factors and the diagnosis of carbohydrate metabolism disorders. Aim of the study. The study aims at determining socio-economic variables, lifestyle behaviours and biological factors differentiating patients with newly diagnosed diabetes from the diabetes-free individuals according to the American criteria issued by the Commission on Social Determinants of Health as well as FINDRISC form which helps identify patients who are at risk of developing diabetes type 2 on the basis of multi-factorial determinants of its development. Material and methods. The res…

Increased plasma resistin concentrations are associated with atherogenic small, dense low-density lipoproteins in patients with type-2 diabetes

2010

Ruokailutottumukset ja tietoisuus tyypin 2 diabeteksen riskitekijöistä : 5 -vuoden seurantatutkimus aikaisemmin tunnistamattomilla tyypin 2 diabeteks…

2013

Laura Nyrövaara (2013). Ruokailutottumukset ja tietoisuus tyypin 2 diabeteksen riskiteki-jöistä: 5-vuoden seurantatutkimus aikaisemmin tunnistamattomilla tyypin 2 diabetekseen sairastuneilla, heikentyneet sokeriarvot omaavilla ja diabetesta sairastamattomilla. Terveys-tieteiden laitos, Jyväskylän yliopisto, Liikuntalääketieteen pro gradu –tutkielma, 38 sivua, 2 liitettä. Tutkimus on osa Terveyden ja hyvinvoinnin laitoksen FINRISKI 2002 Seurantatutkimusta, jonka tarkoituksena oli selvittää diabeteksen ja muiden glukoosiaineenvaihdunnan häiriöiden esiintyvyys väestössä. Tämän tutkielman tarkoituksena oli selvittää onko ruokailutottumuk-sissa ja tietoisuudessa tyypin 2 diabeteksen riskitekijöi…