Search results for "2250*"

Human sweat odour conjugates in human milk, colostrum and amniotic fluid

2012

International audience; Using ultra performance liquid chromatography-mass spectrometry we identified for the first time glutamine-N-alpha-conjugates of the fatty acids (E)/(Z)-3-methylhex-2-enoic acid and (R)/(S)-3-hydroxy-3-methylhexanoic acid as well as cysteinylglycine-S-conjugates of (R)/(S)-3-methyl-3-sulphanylhexan-1-ol and (R)/(S)-3-sulphanylhexan-1-ol as constituents of human milk and colostrum. The glutamine-N-alpha-conjugates were detected also in human amniotic fluids. The mean values of glutamine-N-alpha-conjugate of (R)/(S)-3-hydroxy-3-methylhexanoic acid were highest in colostrums with a range of <0.1-382 mu g/kg, followed by the mature human milk with values from <0.1 to 39.…

Contribución de Anales de Pediatría a la visibilidad internacional de la investigación pediátrica española en la Web of Science (2010-2014)

2016

Resumen: Objetivo: Describir el papel de Anales de Pediatría en la difusión de la investigación pediátrica española e identificar las revistas con las que compite internacionalmente. Material y método: Se identificó la producción pediátrica española y la de Anales de Pediatría recogida en la categoría Pediatrics del Science Citation Index de la WoS (2010-2014) analizando su volumen y tipo documental. De los artículos originales y revisiones (artículos) se estudiaron el año, la citación y el tipo de revista de publicación (revistas generales y especializadas). De las generales, se analizó su productividad de acuerdo con su idioma, posición que ocupa en los JCR de 2012 y accesibilidad a sus c…

Infantile intranuclear rod myopathy.

1997

This report concerns three unrelated floppy infants, two girls and one boy, each biopsied at the age of 1 month. They were hypotonic since birth and required artificial ventilation. The two girls died at the ages of 4 and 3½ months, respectively, the boy is still alive at the age of 2 years, but requires assisted ventilation. Each of the three infants showed, by muscle biopsy, abundant intranuclear rods, the boy and one girl also had sarcoplasmic rods, which were not present in the other girl's muscle. Absence of sarcoplasmic rods, but the presence of intranuclear rods could also be documented in her autopsied muscle. Using an antibody against α-actinin, immunoelectron microscopy showed re…

Zvaigžņotā Debess: 2009/10, Ziema (206)

2009

Contents: TASS and Soviet Press materials. Flight of the Group of Three Soviet Spaceships ; Soviet and Foreign Press materials. Second Expedition on the Moon ; Č.Šklennik. Excursion to an Ancient Laboratory ; M.Gills. Opening Address ; Conference “Astronomy in Latvia” Programme ; From Presentation Abstracts ; I.Pundure. First Enterprise of this Kind ; N.Cimahoviča. Astronomical Contribution to Culture ; A.Alksnis. First Findings of Space Mission CoRoT ; I.Pundure. Ten Years of Chandra Hot Universe Exploration ; M.Gills. The Beginning of Autumn with Astronomy ; Buying Stars and Star Names (translation from IAU) ; I.Pundure. Arturs Balklavs and Astronomy of Latvia (1990-1997) ; J.Jaunbergs. A…

Discurso político y democracia de audiencias: los desafíos discursivos de la digitalización

2020

Antonio Ballester Vilaseca, escultor. : Etapa valenciana: 1910-1940

2013

Branched-Chain and Aromatic Amino Acids Are Associated With Insulin Resistance During Pubertal Development in Girls.

2018

Cross-sectional studies in children show branched-chain and aromatic amino acids are associated with insulin resistance, but whether these associations persist from childhood to adulthood is not known. This study aimed to assess whether circulating amino acids associate with insulin resistance during pubertal development.This was a 7.5-year longitudinal study from childhood to early adulthood. A total of 396 nondiabetic Finnish girls aged 11.2 ± .8 years at baseline participated in the study which was conducted at the Health Science Laboratory, University of Jyväskylä. Serum concentrations of glucose and insulin were determined by enzymatic photometric methods and amino acids by nuclear mag…

Intronic Variant in CNTNAP2 Gene in a Boy With Remarkable Conduct Disorder, Minor Facial Features, Mild Intellectual Disability, and Seizures

2020

Introduction: Mutations in the contactin-associated protein-like 2 (CNTNAP2) gene (MIM#604569) encoding for CASPR2, a cell adhesion protein of the neurexin family, are known to be associated with autism, intellectual disability, and other neuropsychiatric disorders. A set of intronic deletions of CNTNAP2 gene has also been suggested to have a causative role in individuals with a wide phenotypic spectrum, including Pitt-Hopkins syndrome, cortical dysplasia–focal epilepsy syndrome, Tourette syndrome, language dysfunction, and abnormal behavioral manifestations. Case presentation: A 10-years-old boy was referred to the hospital with mild intellectual disability and language impairment. Moreove…

Cerebellum and Prematurity: A Complex Interplay Between Disruptive and Dysmaturational Events.

2021

The cerebellum plays a critical regulatory role in motor coordination, cognition, behavior, language, memory, and learning, hence overseeing a multiplicity of functions. Cerebellar development begins during early embryonic development, lasting until the first postnatal years. Particularly, the greatest increase of its volume occurs during the third trimester of pregnancy, which represents a critical period for cerebellar maturation. Preterm birth and all the related prenatal and perinatal contingencies may determine both dysmaturative and lesional events, potentially involving the developing cerebellum, and contributing to the constellation of the neuropsychiatric outcomes with several impl…

Cobalt bis(dicarbollides)(1-) covalently attached to the calyx[4]arene platform: the first combination of organic bowl-shaped matrices and inorganic …

2005

Various calix[4]arene and resorc[4]arene ionic compounds substituted by cobalt bis(dicarbollide) anions (1) have been prepared for the first time. From tBu-calix[4]arene (A) the complete series of mono-, di-, tri- and tetrasubstituted derivatives bearing one to four cluster anions on the lower rim (3-6) have been obtained in the form of their alkali-metal salts by O-alkylation with the 1-dioxane derivative [8-O(CH2CH2)2O(+)-1,2-C2B9H10)-(1',2'-C2B9H11)-3,3'-Co] (2), all of which are syn or cone isomers. In contrast, disubstitution of the dipropyl ether of tBu-calix[4]arene (B) led to a mixture of the cone and 1,3-alternate conformers 7a and 7b, respectively. Starting from tetrapropoxy-calix…