Search results for "240"
showing 10 items of 1144 documents
Optimización de los procedimientos genético preimplantacional realizados mediante la hibridación in situ de sondas fluorescentes (FISH) en el program…
2015
Los avances en las técnicas de biología molecular y citogenética han propiciado el desarrollo y aplicación del Diagnóstico Genético Preimplantacional (DGP) en las Técnicas de Reproducción Asistida (TRA). Las TRA, por lo general, son empleadas para solventar los problemas de infertilidad, pero además mediante el DGP podemos seleccionar los embriones sanos cromosómicamente normales que van a ser transferidos al útero. El primer ciclos de DGP se realizó en 1989 en una pareja con un alto riesgo de transmitir la enfermedad ligada al sexo. Desde la aparición del primer informe sobre el DGP aplicado clínicamente tanto el número de centros que se aplica el DGP como el número de tratamientos han ido…
De la biotecnologia a la biologia sintètica
2015
Las bacterÃas representan una biodiversidad crÃptica e imperceptible que solo detectamos cuando se convierte en patógena. Sin embargo son omnipresentes en los ecosistemas y generan un continuo entre ellos. Muchas de ellas viven en ambientes extremos y sus genes contienen información clave para solucionar problemas biotecnológicos importantes. Música: Elektrique by Fortadelis Producció: Servei de Formació Permanent i Innovació Educativa (http://www.uv.es/sfpie)
¿Podrían un elefante y una margarita aparearse y tener descendencia?
2015
Durante los últimos doce mil años el hombre ha modificado genéticamente las especies de plantas y animales que ha necesitado para alimentarse o para obtener medicamentos, colorantes o fibras. En la conferencia se expondrán las diferentes estrategias utilizadas para la mejora de las plantas con especial referencia al desarrollo de las técnicas de transformación genética y de genética reversa que permiten superar las barreras sexuales de la mejora tradicional basada en la hibridación. La ingeniería genética permite introducir en las plantas genes concretos de forma controlada, sin importar de qué organismo se hallan aislado, para conseguir la incorporación de nuevas propiedades. Reflexionarem…
Estudio de la función de los factores de transcripción PBX en la diferenciación a neurona dopaminérgica del bulbo olfatorio de ratón
2017
[EN] Dopamine signalling regulates a variety of complex behaviours and defects in dopaminergic neuron function or survival result in severe human pathologies such as Parkinson´s disease. All dopaminergic neurons are characterized by the expression of a battery of genes that code for a set of proteins required for the synthesis, release and re-uptake of dopamine and all together are called the DA pathway genes. Therefore, understanding how this set of genes are transcriptionally activated in a coordinated manner is the first step to discover the clues of dopaminergic terminal differentiation. The dopamine pathway genes are highly conserved throughout evolution. Studies in the nematode C.eleg…
ETIOBE: Un protocolo de intervención para la obesidad infantil apoyado en las tecnologías de la información y la comunicación
2015
El sobrepeso y la obesidad infantil, constituyen hoy en día un grave problema de salud en todo el mundo. La elevada prevalencia de la obesidad infantil ha llevado a que países como Estados Unidos y Europa inviertan en recursos físicos y económicos para desarrollar estrategias capaces de paliar y frenar este alarmante incremento. Sin embargo, a pesar de todo este esfuerzo, la realidad muestra cómo cada vez son más las personas afectadas de este problema. Este problema adquiere una gran magnitud debido a las consecuencias físicas, psicológicas y sociales asociadas al mismo. Ante esta problemática surge la necesidad de desarrollar programas de intervención eficaces, capaces de lograr no sólo e…
Derecho de acceso a la información : el desafío de una sociedad guiada por la transparencia en el ordenamiento jurídico español
2021
This study will address the two aspects of rights linked to information, the right to information and the right to information, to end with the formulation of some conclusions that, distancing themselves from a mere summary, seek to encourage doctrinal and political debate on assumptions that, being peacefully settled, should be reformulated in light of the repeated crisis of transparency. For this, it will be articulated by addressing, first, the most significant aspects of the right to information and its link with the right to freedom of expression, as well as the new challenges that these rights face in the digital age, to then analyze the right to information, its regulation in the Spa…
Universities' mundaneness and regional engagement : Setting the stage
2022
This chapter introduces the main logic of this volume, which starts from the grassroots level of universities’ “everyday” engagements, looking at the manifold ways in which university knowledge agents build connections with multiple regional partners across the public and private sectors, and civic society more generally. Roles, functions and normative orientations of universities in the context of their surrounding regions have, in many cases, been taken for granted and, thus, have not been systematically addressed and/or still lack theorizing, due to the focus being on extraordinary, large-scale and eye-catching activities, and financially impressive transactions such as patents and spin-…
Universities and regions: New insights and emerging developments
2022
In this concluding chapter, the editors take stock of the empirical findings across the cases and levels of analysis and link the empirical evidence to the analytical framework presented in Chapter 2. In so doing, we revisit the interplay between macro, meso, and micro dimensions of the environments as well as the temporality in which higher education institutions (HEIs) operate, which, taken together, help shape the mundane (everyday) or routine behaviours of actors within HEIs. The editors conclude by suggesting that the empirical evidence and conceptual insights advanced in this volume represent a needed first step, yet more needs to be done (future studies) to further unpack how the dyn…
Unpacking Mundaneness : A novel conceptual framework for universities and regional engagement
2022
In this chapter, we debate the current view on university-regional engagements and suggest a renewed theoretical framework based on four main elements – macro, meso, micro dimensions, as well as a meta-dimension of temporality that cuts across all levels. The macro environment is typically defined as pertaining to public policies, culture, laws, and economy, while the meso environment includes links between the macro (societal) forces and the micro (agents) level through intermediate institutions and structures and is characterized by the processes and mechanisms of interaction of different actors. The micro level is about agency – organizations or individuals/groups within organizations – …
Cabbage and fermented vegetables: from death rate heterogeneity in countries to candidates for mitigation strategies of severe COVID-19
2021
International audience; Large differences in COVID-19 death rates exist between countries and between regions of the same country. Some very low death rate countries such as Eastern Asia, Central Europe, or the Balkans have a common feature of eating large quantities of fermented foods. Although biases exist when examining ecological studies, fermented vegetables or cabbage have been associated with low death rates in European countries. SARS-CoV-2 binds to its receptor, the angiotensin-converting enzyme 2 (ACE2). As a result of SARS-CoV-2 binding, ACE2 downregulation enhances the angiotensin II receptor type 1 (AT1 R) axis associated with oxidative stress. This leads to insulin resistance …