Search results for "25"

Hydrogen bonding patterns of 7,9-dimethylguanine and its transplatinum(II) complexes

2002

Methylation at the N7 position is one of the most frequently naturally occurring modifications of guanosine. This alteration drastically changes the hydrogen bonding and acid–base properties of the guanine nucleobase. Here we show on the example of the model nucleobase 7,9-dimethylguanine that due to blockage of N7 of the purine ring, new hydrogen bonding patterns occur on the minor groove binding face of this nucleobase involving the ring nitrogen N3 and the exocyclic amino group N2H2. The free 7,9-dimethylguaninium ion and several transplatinum(II) complexes of the this ligand are presented and discussed. Methylation at N7 drastically changes the acid–base and hydrogen bonding properties …

Slow Pyrolysis come metodo per la valorizzazione di rifiuti e biomassa residuale

2022

Patterns of Safety Incidents in a Neonatal Intensive Care Unit

2021

Introduction: Safety incidents preceding manifest adverse events are barely evaluated in neonatal intensive care units (NICUs). This study aimed at identifying frequency and patterns of safety incidents in our NICU.Methods: A 6-month prospective clinical study was performed from May to October 2019 in a German 10-bed level III NICU. A voluntary, anonymous reporting system was introduced, and all neonatal team members were invited to complete paper-based questionnaires following each particular safety incident. Safety incidents were defined as safety-related events that were considered by the reporting team member as a “threat to the patient's well-being” which “should ideally not occur agai…

Heterogeneity in general practitioners’ preferences for quality improvement programs: a choice experiment and policy simulation in France

2016

International audience; Despite increasing popularity, quality improvement programs (QIP) have had modest and variable impacts on enhancing the quality of physician practice. We investigate the heterogeneity of physicians’ preferences as a potential explanation of these mixed results in France, where the national voluntary QIP – the CAPI – has been cancelled due to its unpopularity. We rely on a discrete choice experiment to elicit heterogeneity in physicians’ preferences for the financial and non-financial components of QIP. Using mixed and latent class logit models, results show that the two models should be used in concert to shed light on different aspects of the heterogeneity in prefer…

Quality of life, Body image, and psychiatric implications in patients with urn trauma: preliminary study of the Italian version of Burn Specific Heal…

2010

Burn patients may suffer both physical and psychopatological consequences and their quality of life and the presence of psychopathological symptoms should be evacuate. The Burn Specific Health Scale-Brief (BSHS-B) is a tried and test-instrument for assessing burn patients’ quality of life. The aim of this study is to propose the Italian translation of BSHS-B and presents the preliminary results of an exploratory study. The Italian version of BSHS-B was administered to a sample group of 50 burn victims. Reliability was verified by Cronbach’s alpha, and construct validity was evaluated through correlation with the Short Form 36 Health Survey Questionnaire (SF-36) and the Self-report Symptom I…

Randomized controlled trial of postoperative exercise rehabilitation program after lumbar spine fusion: study protocol

2012

Abstract Background Lumbar spine fusion (LSF) effectively decreases pain and disability in specific spinal disorders; however, the disability rate following surgery remains high. This, combined with the fact that in Western countries the number of LSF surgeries is increasing rapidly it is important to develop rehabilitation interventions that improve outcomes. Methods/design In the present RCT-study we aim to assess the effectiveness of a combined back-specific and aerobic exercise intervention for patients after LSF surgery. One hundred patients will be randomly allocated to a 12-month exercise intervention arm or a usual care arm. The exercise intervention will start three months after su…

Intermolecular structure factors of macromolecules in solution: Integral equation results

1999

The inter-molecular structure of semidilute polymer solutions is studied theoretically. The low density limit of a generalized Ornstein-Zernicke integral equation approach to polymeric liquids is considered. Scaling laws for the dilute-to-semidilute crossover of random phase (RPA) like structure are derived for the inter-molecular structure factor on large distances when inter-molecular excluded volume is incorporated at the microscopic level. This leads to a non-linear equation for the excluded volume interaction parameter. For macromolecular size-mass scaling exponents, $\nu$, above a spatial-dimension dependent value, $\nu_c=2/d$, mean field like density scaling is recovered, but for $\n…

Deeply virtual compton scattering off the neutron.

2007

The present experiment exploits the interference between the Deeply Virtual Compton Scattering (DVCS) and the Bethe-Heitler processes to extract the imaginary part of DVCS amplitudes on the neutron and on the deuteron from the helicity-dependent D$({\vec e},e'\gamma)X$ cross section measured at $Q^2$=1.9 GeV$^2$ and $x_B$=0.36. We extract a linear combination of generalized parton distributions (GPDs) particularly sensitive to $E_q$, the least constrained GPD. A model dependent constraint on the contribution of the up and down quarks to the nucleon spin is deduced.

A quasiconformal composition problem for the Q-spaces

2017

Given a quasiconformal mapping $f:\mathbb R^n\to\mathbb R^n$ with $n\ge2$, we show that (un-)boundedness of the composition operator ${\bf C}_f$ on the spaces $Q_{\alpha}(\mathbb R^n)$ depends on the index $\alpha$ and the degeneracy set of the Jacobian $J_f$. We establish sharp results in terms of the index $\alpha$ and the local/global self-similar Minkowski dimension of the degeneracy set of $J_f$. This gives a solution to [Problem 8.4, 3] and also reveals a completely new phenomenon, which is totally different from the known results for Sobolev, BMO, Triebel-Lizorkin and Besov spaces. Consequently, Tukia-V\"ais\"al\"a's quasiconformal extension $f:\mathbb R^n\to\mathbb R^n$ of an arbitr…

Application of latent class analysis in assessing the awareness, attitude, practice and satisfaction of paediatricians on sleep disorder management i…

2020

Aim To identify subgroups regarding paediatricians’ awareness, attitude, practice and satisfaction about management of Sleep-Disordered Breathing (SDB) in Italy using Latent Class Analysis (LCA). Methods A cross-sectional study was conducted on a large sample of Italian paediatricians. Using a self-administered questionnaire, the study collected information on 420 Paediatric Hospital Paediatricians (PHPs) and 594 Family Care Paediatricians (FCPs). LCA was used to discover underlying response patterns, thus allowing identification of respondent groups with similar awareness, attitude, practice and satisfaction. A logistic regression model was used to investigate which independent variables i…