Search results for "25"
showing 10 items of 3263 documents
Infectious Tolerance
2002
Regulatory CD4(+)CD25(+) T cells (Treg) are mandatory for maintaining immunologic self-tolerance. We demonstrate that the cell-cell contact-mediated suppression of conventional CD4(+) T cells by human CD25(+) Treg cells is fixation resistant, independent from membrane-bound TGF-beta but requires activation and protein synthesis of CD25(+) Treg cells. Coactivation of CD25(+) Treg cells with Treg cell-depleted CD4(+) T cells results in anergized CD4(+) T cells that in turn inhibit the activation of conventional, freshly isolated CD4(+) T helper (Th) cells. This infectious suppressive activity, transferred from CD25(+) Treg cells via cell contact, is cell contact-independent and partially medi…
L’aprenentatge de la pronúncia anglesa mitjançant REO: El cas de Voki
2018
Al llarg dels anys, l’anglès s’ha situat com una vertadera llengua global a la nostra societat. Això ha donat pas a l’aplicació d’un nombre de mètodes i enfocaments pel que fa a l’àrea d’ensenyament i aprenentatge de l’anglès com a llengua estrangera o segona llengua, on tant la integració de les Tecnologies de la Informació i la Comunicació (TIC) com dels Recursos Educatius Oberts (REO) és primordial. Tenint això en compte, aquest estudi té dos objectius. D’una banda, es pretén investigar fins a quin punt els estudiants universitaris matriculats a l’assignatura de Pronunciació i Comprensió de l’ Anglès Oral són capaços de millorar la pronunciació mitjançant l’eina en línia anomenada Voki. …
The Mitochondrial Targeting Chaperone 14-3-3ε Regulates a RIG-I Translocon that Mediates Membrane Association and Innate Antiviral Immunity
2012
SummaryRIG-I is a cytosolic pathogen recognition receptor that initiates immune responses against RNA viruses. Upon viral RNA recognition, antiviral signaling requires RIG-I redistribution from the cytosol to membranes where it binds the adaptor protein, MAVS. Here we identify the mitochondrial targeting chaperone protein, 14-3-3ε, as a RIG-I-binding partner and essential component of a translocation complex or “translocon” containing RIG-I, 14-3-3ε, and the TRIM25 ubiquitin ligase. The RIG-I translocon directs RIG-I redistribution from the cytosol to membranes where it mediates MAVS-dependent innate immune signaling during acute RNA virus infection. 14-3-3ε is essential for the stable inte…
Cytokine Polymorphism in Takotsubo Cardiomyopathy
2014
IMIN11. Cytokine Polymorphism in Takotsubo Cardiomyopathy P. Di Gangi1, L. Scola1, S. Giambanco1, M. Bova1, G. Santini1, L. Vaccarino1, C. R. Balistreri1, D. Lio1, P. Assennato1, S. Novo1, G. Novo1 1University of Palermo, Palermo, Italy Background: Takotsubo (TT) cardiomyopathy is characterised by an acute left ventricular dysfunction triggered by emotional or physical stresses. Clinically, the syndrome is characterised by acute symptoms mimicking acute infarction without relevant electrocardiographic and biochemical markers of myocardial damage changes. Stressful events inducing an excess catecholamine release and myocardial β-adrenergic receptors (β-AR) seem to play a major role in TT. Ac…
Polythiophenes as markers of asphalt and archaeological tar pitch aging. Characterization using solid-state electrochemistry
2018
The voltammetry of immobilized microparticles (VIMP) was used to characterize organosulfur components from ovens found at the Spanish archaeological sites of Cueva de Nerja (ca. 35,000cal BC), la Illeta dels Banyets (4th century BCE) and Gestalgar (12th–13th CE), and asphalt probes subjected to PAV and SUNTEST aging protocols. The voltammetric responses of the archaeological samples and the asphalt probes after photodegradation were quite similar, indicating the presence of polythiophene components which could act as age/degradation markers. Keywords: Voltammetry, Archaeology, Asphalt, Tar pitch, Organosulfur compounds
Relationships between early flavor exposure, and food acceptability and neophobia
2016
Revue; In the first section of this chapter, an overview of what is known about early flavor exposure, distinguishing between taste and flavor (aroma) exposure is provided. In the second section, we will describe what has been researched regarding the influence of early flavor exposure on the development of food preference, looking at prenatal exposure, exposure received in the context of milk feeding and exposure received in the context of complementary feeding. The third section is a description of what has been shown regarding the relationships between early flavor exposure and food neophobia. The chapter ended with a comment on likely future trends, and by a description of sources of fu…
Slow Pyrolysis as a Method for Biochar Production from Carob Waste: Process Investigation and Products’ Characterization
2021
The zero-waste city challenge of the modern society is inevitably addressed to the development of model’s waste-to-energy. In this work, carob waste, largely used in the agro-industrial sector for sugar extraction or locust beangum (LBG) production, is considered as feedstock for the slow pyrolysis process. According to the Food and Agriculture Organization of the United Nations (FAO), in 2012, the world production of carobs was ca. 160,000 tons, mainly concentrated in the Mediterranean area (Spain, Italy, Morocco, Portugal, and Greece). To evaluate the biomass composition, at first, the carob waste was subjected to thermo-gravimetric analysis. The high content of fixed carbon suggest…
Technostress: a research study about computer self-efficacy, Internet attitude and computer-anxiety
2008
The current study describes a particular kind of techno-stress related to computer use, defined as computer anxiety and its psychological correlates: computer-expertise, computer self-efficacy and internet attitudes.
Robust γ-filter using support vector machines
2009
This Letter presents a new approach to time-series modelling using the support vector machines (SVM). Although the g-filter can provide stability in several time-series models, the SVM is proposed here to provide robustness in the estimation of the g-filter coefficients. Examples in chaotic time-series prediction and channel equalization show the advantages of the joint SVM g-filter. Teoría de la Señal y Comunicaciones
A Simple Fusion Method for Image Time Series Based on the Estimation of Image Temporal Validity
2015
High-spatial-resolution satellites usually have the constraint of a low temporal frequency, which leads to long periods without information in cloudy areas. Furthermore, low-spatial-resolution satellites have higher revisit cycles. Combining information from high- and low- spatial-resolution satellites is thought a key factor for studies that require dense time series of high-resolution images, e.g., crop monitoring. There are several fusion methods in the bibliography, but they are time-consuming and complicated to implement. Moreover, the local evaluation of the fused images is rarely analyzed. In this paper, we present a simple and fast fusion method based on a weighted average of two in…