Search results for "25"
showing 10 items of 3263 documents
Sounding Together: Family-Centered Music Therapy as Facilitator for Parental Singing During Skin-to-Skin Contact
2017
Introduction: When it comes to the delicate relationship between a baby and its parents, the voices of the parents have a significant role in communicating love, tenderness, and closeness as well as in supporting self-regulation as necessary for secure attachment. Under suboptimal experiences, such as premature birth, infant-directed singing takes on an even more important and therapeutic role since preterm infants miss the finely attuned auditory stimulation of the womb and the mother-infant dyad is disrupted too early.
Extracellular Vesicle microRNAs Contribute to the Osteogenic Inhibition of Mesenchymal Stem Cells in Multiple Myeloma
2020
Osteolytic bone disease is the major complication associated with the progression of multiple myeloma (MM). Recently, extracellular vesicles (EVs) have emerged as mediators of MM-associated bone disease by inhibiting the osteogenic differentiation of human mesenchymal stem cells (hMSCs). Here, we investigated a correlation between the EV-mediated osteogenic inhibition and MM vesicle content, focusing on miRNAs. By the use of a MicroRNA Card, we identified a pool of miRNAs, highly expressed in EVs, from MM cell line (MM1.S EVs), expression of which was confirmed in EVs from bone marrow (BM) plasma of patients affected by smoldering myeloma (SMM) and MM. Notably,we found that miR-129-5p, whic…
Transexualidad y Adolescencia: Una revisión sistemática
2018
El estudio de la transexualidad ha evolucionado en los últimos años alcanzando mayor visibilidad actualmente gracias a las iniciativas de los colectivos trans y al incremento de niños, niñas y adolescentes que acuden a atención primaria por problemas de identidad de género. Este creciente interés ha estimulado la investigación cuya abundancia precisa un análisis y selección de los trabajos más relevantes. Con este objetivo hemos realizado una revisión bibliográfica con el fin de abordar el estado actual de la transexualidad temprana, centrándonos en los estudios relativos a su etiología, prevalencia, diagnóstico y tratamientos actuales. Para ello se consultaron diversas bases de datos (Web …
Qualità di Vita, immagine del corpo e complicanze psichiatriche in pazienti con trauma da ustione
2009
Divergent Patterns and Trends in Breast Cancer Incidence, Mortality and Survival Among Older Women in Germany and the United States
2020
Background: Breast cancer treatment has changed tremendously over the last decades. In addition, the use of mammography screening for early detection has increased strongly. To evaluate the impact of these developments, long-term trends in incidence, mortality, stage distribution and survival were investigated for Germany and the United States (US). Methods: Using population-based cancer registry data, long-term incidence and mortality trends (1975&ndash
Extracellular Vesicles as Shuttles of Tumor Biomarkers and Anti-Tumor Drugs
2014
Extracellular vesicles (EV) include vesicles released by either normal or tumor cells. EV may exceed the nanometric scale (microvesicles), or to be within the nanoscale, also called exosomes. Thus, it appears that only exosomes and larger vesicles may have the size for potential applications in nanomedicine, in either disease diagnosis or therapy. This is of particular interest for research in cancer, also because the vast majority of existing data on EV are coming from pre-clinical and clinical oncology. We know that the microenvironmental features of cancer may favor cell-to-cell paracrine communication through EV, but EV have been purified, characterized, and quantified from plasma of tu…
Sisäistyneet ristiriidat, tunnetyö ja tietotyöläissubjektiviteetin rakentuminen
2015
Yliopistotyö on esimerkki uuden työn muodoista, joissa työ kiinnittyy aiempaa vahvemmin yksilöön. Samalla vastuu työelämän vaatimuksiin yltämisestä siirtyy työntekijälle itselleen. Työyhteisön ristiriitatilanteissa organisaation ongelmat sisäistyvät työntekijän yksityisiksi ja tunne-elämän ongelmiksi.
Kliinisestä harjoittelusta työssäoppimiseen ja yhteistyötiimeihin
2002
Terveysalan työharjoittelun toteutumista on arvosteltu siitä, että oppilaitokset panostavat entistä vähemmän työharjoittelun ohjaukseen ja harjoittelupaikkojen kanssa tehtävään yhteistyöhön. Harjoittelussa perinteiset työtavat ja vallitseva työkulttuuri siirretään kritiikittömästi opiskelijoille. Koulun antamat tiedot ja harjoittelupaikan edellyttämät taidot eivät kohtaa. Artikkelissa luodaan näkymiä uudenlaiseen työssäoppimiseen tehostamalla koulun ja työpaikkojen välistä yhteistyötä.
Joan B. Llinares, una reflexión filosófica a través de la literatura
2020
Influence of Viscosity on Mass Transfer Performance of Unbaffled Stirred Vessels
2013
Unbaffled stirred tanks are seldom employed in the process industry as they are considered poorer mixers than baffled vessels. However they may be expected to provide significant advantages in a wide range of applications (e.g. crystallization, food and pharmaceutical processes, etc) where the presence of baffles is often undesirable. Moreover, in plants or animal cell cultivation bioreactors, where cell damage is often caused by bursting bubbles at the air –medium interface (Barret et al., 2010), they can provide sufficient mass transfer through the free surface vortex, so bubble formation and subsequent bursting inside the reactor can be conveniently avoided (Scargiali et al., 2012). In t…