Search results for "2R"
showing 10 items of 93 documents
CCDC 922681: Experimental Crystal Structure Determination
2013
Related Article: Ferenc Miklós, István M. Mándity, Reijo Sillanpää, Ferenc Fülöp|2013|Tetrahedron Lett.|54|3769|doi:10.1016/j.tetlet.2013.05.009
CCDC 1814031: Experimental Crystal Structure Determination
2018
Related Article: Guocheng Deng, Sami Malola, Juanzhu Yan, Yingzi Han, Peng Yuan, Chaowei Zhao, Xiting Yuan, Shuichao Lin, Zichao Tang, Boon K. Teo, Hannu Häkkinen, Nanfeng Zheng|2018|Angew.Chem.,Int.Ed.|57|3421|doi:10.1002/anie.201800327
CCDC 704876: Experimental Crystal Structure Determination
2009
Related Article: L.Kiss, E.Forro, R.Sillanpaa, F.Fulop|2008|Tetrahedron:Asymm.|19|2856|doi:10.1016/j.tetasy.2008.11.035
Chlorophyll and Suspended Solids Estimation in Portuguese Reservoirs (Aguieira and Alqueva) from Sentinel-2 Imagery
2021
Reservoirs have been subject to anthropogenic stressors, becoming increasingly degraded. The evaluation of ecological potential in reservoirs is remarkably challenging, and consistent and regular monitoring using the traditional in situ methods defined in the WFD is often time- and money-consuming. Alternatively, remote sensing offers a low-cost, high frequency, and practical complement to these methods. This paper proposes a novel approach, using a C2RCC processor to analyze Sentinel-2 imagery data to retrieve information on water quality in two reservoirs of Portugal, Aguieira and Alqueva. We evaluate the temporal and spatial evolution of Chl a and total suspended solids (TSS), between 20…
SNP variation in the bitter taste TAS2R38 gene evaluated in student populations of several italian universities and isolates
2007
People vary widely in their sensitivities to bitter compounds, but the all intercorrelation of these sensitivities is unknown. The study of genetic influences on bitter taste perception originated from the discovery in the 1930s that some individuals had taste to phenylthiocarbamide(PTC), whereas others found it extremely bitter. Subsequently, many studies were carried out on PTC and the structurally related compound propylthiouracil (PROP) to assess this viability and to determine the root causes. Initial family studies strongly suggested that PTC no tasting was due to a recessive allele in a single gene and heritability was estimated at 0,5. 55-85% of variation in PTC detection. The PTC ge…
Interpreting Heterogeneous Geospatial Data Using Semantic Web Technologies
2016
International audience; The paper presents work on implementation of semantic technologies within a geospatial environment to provide a common base for further semantic interpretation. The work adds on the current works in similar areas where priorities are more on spatial data integration. We assert that having a common unified semantic view on heterogeneous datasets provides a dimension that allows us to extend beyond conventional concepts of searchability, reusability, composability and interoperability of digital geospatial data. It provides contextual understanding on geodata that will enhance effective interpretations through possible reasoning capabilities. We highlight this through …
Saveur amère : de la molécule au comportement
2020
La saveur amère permet aux mammifères d’éviter l’ingestion d’aliments poten-tiellement contaminés par des substances amères toxiques fréquemment retrouvées dans notre environnement. La détection de ces molécules aux structures chimiques diverses est réalisée par une famille de récepteurs appelés TAS2R. L’être humain est pourvu de 25 TAS2R aux spectres de reconnaissance plus ou moins larges pour détecter un grand nombre de molécules amères. Des tests fonctionnels in vitro ont été développés afin de détermi-ner le profil d’activation des TAS2R humains. De nombreuses molécules, d’origines natu-relles ou synthétiques ont pu être identifiées comme capable d’activer ces TAS2R. Ces tests fonctionn…
Impact du système endocannabinoïdien sur la physiologie de l'obésité : effets de l'antagonisme des récepteurs CB1 sur le métabolisme glucido-lipidiqu…
2010
The endocannabinoïd system (ECS) is involved in many biological functions such as regulation of energy metabolism. Recently, several studies have shown an association between obesity and ECS overactivity. In addition, specific CB1R antagonists such as Rimonabant (SR141716) improved metabolic parameters in obese patients essentially through inactivation of central CB1R. However, peripheral CB1R inactivation could also contribute to the improvement of these parameters and it is this notion that we have studied. To this purpose, we tested the effects of SR141716 on obese mice in order to establish relationships between the ECS activity and lipid metabolism by looking more specifically to its r…
CCDC 139658: Experimental Crystal Structure Determination
2001
Related Article: P.Lahuerta, E.Moreno, A.Monge, G.Muller, J.Perez-Prieto, M.Sanau, S.-E.Stiriba|2000|Eur.J.Inorg.Chem.||2481|doi:10.1002/1099-0682(200012)2000:12<2481::AID-EJIC2481>3.0.CO;2-M
Melanokortīna otrā tipa receptora un tā palīgproteīna ekspresija rauga Pichia Pastoris ekspresijas sistēmā
2015
Darba ietvaros tika izveidots pPIC9K- MC2R-T4L ekspresijas konstrukts, kas tika ekspresēts P.Pastoris sistēmā. Western blot analīze uzrādīja nepieciešamās molekulmasas zonu. MC2R-T4L izdevās attīrīt uz His- un Ha-tag afinitātes kolonnām. Lai noteiktu funkcionāla MC2R struktūru, to nepiecieciešams ekspresēt kompleksā ar MRAP, tādēļ tika izveidoti vairāki MC2-MRAP konstrukti, ko tālāk izmantot proteīna ekspresijai P. Pastoris šūnās. To aktivitāte tika pārbaudīta zīdītāju šūnu līnijās nosakot cAMP daudzuma izmaiņas pēc stimulācijas ar ACTH (1-24). Iegūtie rezultāti bija nestabili, tādēļ tālākajos pētījumos tiks veikta radioaktīvā ACTH saistīšanas mērījumus. Darbs tika veikts no 2013.gada jūnij…