Search results for "2a"
showing 10 items of 282 documents
CCDC 1583212: Experimental Crystal Structure Determination
2018
Related Article: Nicolas Sok, Claire Bernhard, Pauline Désogère, Christine Goze, Yoann Rousselin, Frédéric Boschetti, Isabelle Baglin, Franck Denat|2018|Eur.J.Org.Chem.|2018|4762|doi:10.1002/ejoc.201800801
CCDC 136298: Experimental Crystal Structure Determination
2002
Related Article: A.J.Ayling, S.Broderick, J.P.Clare, A.P.Davis, M.N.Perez-Payan, M.Lahtinen, M.J.Nissinen, K.Rissanen|2002|Chem.-Eur.J.|8|2197|doi:10.1002/1521-3765(20020503)8:9<2197::AID-CHEM2197>3.0.CO;2-J
CCDC 635027: Experimental Crystal Structure Determination
2008
Related Article: A.Valkonen, E.Kolehmainen, M.Lahtinen, E.Sievanen, V.Noponen, M.Tolonen, R.Kauppinen|2007|Molecules|12|2161|doi:10.3390/12092161
CCDC 667968: Experimental Crystal Structure Determination
2009
Related Article: A.Valkonen, M.Lahtinen, E.Kolehmainen|2008|Steroids|73|1228|doi:10.1016/j.steroids.2008.06.006
CCDC 1583209: Experimental Crystal Structure Determination
2018
Related Article: Nicolas Sok, Claire Bernhard, Pauline Désogère, Christine Goze, Yoann Rousselin, Frédéric Boschetti, Isabelle Baglin, Franck Denat|2018|Eur.J.Org.Chem.|2018|4762|doi:10.1002/ejoc.201800801
CCDC 841799: Experimental Crystal Structure Determination
2012
Related Article: V.Noponen, H.Belt, M.Lahtinen, A.Valkonen, H.Salo, J.Ulrichova, A.Galandakova, E.Sievanen|2012|Steroids|77|193|doi:10.1016/j.steroids.2011.11.006
CCDC 1583211: Experimental Crystal Structure Determination
2018
Related Article: Nicolas Sok, Claire Bernhard, Pauline Désogère, Christine Goze, Yoann Rousselin, Frédéric Boschetti, Isabelle Baglin, Franck Denat|2018|Eur.J.Org.Chem.|2018|4762|doi:10.1002/ejoc.201800801
The histone deacetylase Rpd3 regulates the heterochromatin structure of Drosophila telomeres
2011
Telomeres are specialized structures at the end of eukaryotic chromosomes that are required to preserve genome integrity, chromosome stability and nuclear architecture. Telomere maintenance and function are established epigenetically in several eukaryotes. However, the exact chromatin enzymatic modifications regulating telomere homeostasis are poorly understood. In Drosophila melanogaster, telomere length and stability are maintained through the retrotransposition of specialized telomeric sequences and by the specific loading of protecting capping proteins, respectively. Here, we show that the loss of the essential and evolutionarily conserved histone deacetylase Rpd3, the homolog of mammal…
D2R striatopallidal neurons inhibit both locomotor and drug reward processes.
2009
The specific functions of dopamine D(2) receptor-positive (D(2)R) striatopallidal neurons remain poorly understood. Using a genetic mouse model, we found that ablation of D(2)R neurons in the entire striatum induced hyperlocomotion, whereas ablation in the ventral striatum increased amphetamine conditioned place preference. Thus D(2)R striatopallidal neurons limit both locomotion and, unexpectedly, drug reinforcement.
The modulator is a constitutive enhancer of a developmentally regulated sea urchin histone H2A gene.
2002
Going back to the late 1970s and early 1980s, we trace the Xenopus oocyte microinjection experiments that led to the emergence of the concept of “modulator”. The finding that the modulator could transactivate transcription from far upstream and in either orientation suggested that a new genetic element, different from the classical prokaryotic promoter sequences, had been discovered. This particular enhancer transactivates transcription of the sea urchin early (α) histone H2A gene which is regulated in early sea urchin development. We summarise the data from sea urchin microinjection experiments that confirm and extend the results obtained with Xenopus oocytes. We conclude that the H2A enha…