Search results for "3-MA"

showing 10 items of 23 documents

Dehn surgeries and smooth structures on 3-dimensional transitive Anosov flows.

2020

The present thesis is about Dehn surgeries and smooth structures associated with transitive Anosov flows in dimension three. Anosov flows constitute a very important class of dynamical systems, because of its persistent chaotic behaviour, as well as for its rich interaction with the topology of the ambient space. Even if a lot is known about the dynamical and ergodic properties of these systems, there is not a clear understanding about how to classify its different orbital equivalence classes. Until now, the biggest progress has been done in dimension three, where there is a family of techniques intended for the construction of Anosov flows called surgeries.During the realization of this th…

3-ManifoldsHyperbolic DynamicsDehn surgeriesFlots d' AnosovDynamique hyperboliqueSections de BirkhoffDécompositions en livre ouvert[MATH.MATH-GN] Mathematics [math]/General Topology [math.GN]Chirurgies de DehnOpen book decompositions[MATH.MATH-GN]Mathematics [math]/General Topology [math.GN]Anosov flowsBirkhoff sections3-Variétés
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On the hyperbolic limit points of groups acting on hyperbolic spaces

1998

We study the hyperbolic limit points of a groupG acting on a hyperbolic metric space, and consider the question of whether any attractive limit point corresponds to a unique repulsive limit point. In the special case whereG is a (non-elementary) finitely generated hyperbolic group acting on its Cayley graph, the answer is affirmative, and the resulting mapg +↦g −, is discontinuous everywhere on the hyperbolic boundary. We also provide a direct, combinatorial proof in the special case whereG is a (non-abelian) free group of finite type, by characterizing algebraically the hyperbolic ends ofG.

Discrete mathematicsPure mathematicsHyperbolic groupGeneral MathematicsHyperbolic 3-manifoldHyperbolic angleHyperbolic manifoldUltraparallel theoremRelatively hyperbolic groupMathematicsHyperbolic equilibrium pointHyperbolic treeRendiconti del Circolo Matematico di Palermo
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Topological classification of gradient-like diffeomorphisms on 3-manifolds

2004

Abstract We give a complete invariant, called global scheme , of topological conjugacy classes of gradient-like diffeomorphisms, on compact 3-manifolds. Conversely, we can realize any abstract global scheme by such a diffeomorphism.

Discrete mathematicsPure mathematicsMathematics::Dynamical SystemsTopological classificationTopological classificationGeometry and TopologyDiffeomorphismInvariant (mathematics)Topological conjugacyMathematics::Symplectic GeometryMorse–Smale diffeomorphismsMathematics3-manifoldsTopology
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The Intersection of $3$-Maximal Submonids

2020

Very little is known about the structure of the intersection of two $k$-generated monoids of words, even for $k=3$. Here we investigate the case of $k$-maximal monoids, that is, monoids whose basis of cardinality $k$ cannot be non-trivially decomposed into at most $k$ words. We characterize the intersection in the case of two $3$-maximal monoids.

Free graphSettore INF/01 - InformaticaGeneral Computer ScienceMathematics::Category Theory3-maximal monoidsMathematics - CombinatoricsComputer Science - Formal Languages and Automata Theory68R15IntersectionTheoretical Computer Science
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Total curvatures of convex hypersurfaces in hyperbolic space

1999

We give sharp upper estimates for the difference circumradius minus inradius and for the angle between the radial vector (respect to the center of an inball) and the normal to the boundary of a compact $h$-convex domain in the hyperpolic space. We apply these estimates to get the limit at the infinity for the quotients Volume/Area and (Total $k$-mean curvature)/Area of a family of $h$-convex domains which expand over the whole space. The theorem for the first quotient gives an extension to arbitrary dimension of a result of Santalo and Yanez for the hyperbolic plane.

Hyperbolic groupGeneral MathematicsHyperbolic spaceHyperbolic 3-manifoldMathematical analysisHyperbolic angleMathematics::Metric GeometryHyperbolic manifoldUltraparallel theoremHyperbolic triangleRelatively hyperbolic groupMathematicsIllinois Journal of Mathematics
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THE HOROSPHERICAL GEOMETRY OF SUBMANIFOLDS IN HYPERBOLIC SPACE

2005

Some geometrical properties associated to the contact of submanifolds with hyperhorospheres in hyperbolic -space are studied as an application of the theory of Legendrian singularities.

Hyperbolic groupGeneral MathematicsHyperbolic spaceMathematical analysisHyperbolic 3-manifoldHyperbolic manifoldUltraparallel theoremGeometryHyperbolic motionMathematics::Geometric TopologyRelatively hyperbolic groupMathematics::Differential GeometryMathematics::Symplectic GeometryHyperbolic triangleMathematicsJournal of the London Mathematical Society
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Non-equivalent hyperbolic knots

2002

We construct, for each integer n 3, pairs of non-equivalent hyperbolic knots with the same 2fold and n-fold cyclic branched covers. We also discuss necessary conditions for such pairs of knots to exist.  2001 Elsevier Science B.V. All rights reserved. MSC: primary 57M25; secondary 57M12, 57M50

Hyperbolic knotsPure mathematicsQuantitative Biology::BiomoleculesCyclic branched coversHyperbolic groupSkein relationHyperbolic 3-manifoldOrbifoldsHyperbolic manifoldVolume conjectureMathematics::Geometric TopologyBonahon–Siebenmann decompositionKnot theoryAlgebraIntegerGeometry and TopologyMathematicsTopology and its Applications
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The HOMFLY-PT polynomials of sublinks and the Yokonuma–Hecke algebras

2016

We describe completely the link invariants constructed using Markov traces on the Yokonuma-Hecke algebras in terms of the linking matrix and the HOMFLYPT polynomials of sublinks.

MSC: Primary 57M27: Invariants of knots and 3-manifolds Secondary 20C08: Hecke algebras and their representations 20F36: Braid groups; Artin groups 57M25: Knots and links in $S^3$Pure mathematicsMarkov chainGeneral Mathematics010102 general mathematicsYokonuma-Hecke algebrasGeometric Topology (math.GT)Linking numbers01 natural sciencesMathematics::Geometric TopologyMatrix (mathematics)Mathematics - Geometric TopologyMarkov tracesMathematics::Quantum Algebra[MATH.MATH-GT]Mathematics [math]/Geometric Topology [math.GT]0103 physical sciencesMathematics - Quantum AlgebraFOS: MathematicsQuantum Algebra (math.QA)010307 mathematical physics0101 mathematicsRepresentation Theory (math.RT)Link (knot theory)Mathematics - Representation TheoryMathematics
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MCC1019, a selective inhibitor of the Polo-box domain of Polo-like kinase 1 as novel, potent anticancer candidate

2019

Polo-like kinase (PLK1) has been identified as a potential target for cancer treatment. Although a number of small molecules have been investigated as PLK1 inhibitors, many of which showed limited selectivity. PLK1 harbors a regulatory domain, the Polo box domain (PBD), which has a key regulatory function for kinase activity and substrate recognition. We report on 3-bromomethyl-benzofuran-2-carboxylic acid ethyl ester (designated: MCC1019) as selective PLK1 inhibitor targeting PLK1 PBD. Cytotoxicity and fluorescence polarization-based screening were applied to a library of 1162 drug-like compounds to identify potential inhibitors of PLK1 PBD. The activity of compound MC1019 against the PLK1…

PBD Polo box domainMTD maximal tolerance doseCDC25 cell division cycle 25HIF-1α hypoxia-inducible factor 1 αMST microscale thermophoresisIC50 50% inhibition concentrationMFP M phase promoting factorPARP-1 poly(ADP-ribose) polymerase-10302 clinical medicineFOXO forkhead box ONec-1 necrostatin 1CDC2 cell division cycle protein 2 homologGeneral Pharmacology Toxicology and PharmaceuticsMitotic catastropheCDK cyclin-dependent kinase0303 health sciencesChemistryPolo-like kinaseMono-targeted therapyCell cycleBUBR1 budding uninhibited by benzimidazole-related 1Polo box domain030220 oncology & carcinogenesisPLK1 Polo-like kinaseNecroptosisSpindle damagePLK1IHC immunohistochemistryOriginal articleNecroptosisCell cyclePLK1APC/C anaphase-promoting complex/cyclosomePLK3ABC avidin-biotin complexPI propidium iodide03 medical and health sciencesFBS fetal bovine serumPDB Protein Data BankKd the dissociation constantKinase activity030304 developmental biologyAkt/PKB signaling pathwayCell growthlcsh:RM1-950LC3 light chain 3lcsh:Therapeutics. PharmacologyCancer researchDAPKs death-associated protein kinase3-MA 3-methyladenineDAPI 4′6-diamidino-2-phenylindoleSAC spindle assembly checkpointActa Pharmaceutica Sinica B
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Finite type invariants of knots in homology 3-spheres with respect to null LP-surgeries

2017

We study a theory of finite type invariants for null-homologous knots in rational homology 3-spheres with respect to null Lagrangian-preserving surgeries. It is an analogue in the setting of the rational homology of the Goussarov-Rozansky theory for knots in integral homology 3-spheres. We give a partial combinatorial description of the graded space associated with our theory and determine some cases when this description is complete. For null-homologous knots in rational homology 3-spheres with a trivial Alexander polynomial, we show that the Kricker lift of the Kontsevich integral and the Lescop equivariant invariant built from integrals in configuration spaces are universal finite type i…

Pure mathematicsAlexander polynomialPrimary: 57M27Homology (mathematics)01 natural sciencesHomology sphereMathematics::Algebraic TopologyMathematics - Geometric TopologyKnot (unit)Mathematics::K-Theory and Homologybeaded Jacobi diagramknot[MATH.MATH-GT]Mathematics [math]/Geometric Topology [math.GT]0103 physical sciencesFOS: Mathematics0101 mathematicsInvariant (mathematics)Mathematics::Symplectic Geometry3-manifoldhomology sphereMathematicsBorromean surgerycalculus010102 general mathematicsGeometric Topology (math.GT)Kontsevich integral16. Peace & justiceMathematics::Geometric TopologymanifoldsFinite type invariantnull-move57M27Finite type invariantLagrangian-preserving surgeryEquivariant map010307 mathematical physicsGeometry and Topology3-manifold
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