Search results for "302"
showing 10 items of 27399 documents
Estructura - función - especificidad en el ámbito de las transcarbamilasas: la putrescina transcarbamilasa
2012
Para la realización de esta Tesis, Luis Mariano Polo Ilacqua ha disfrutado de una Beca de las Cátedras volantes BSCH-CSIC del Convenio de Colaboración entre el Banco de Santander Central Hispano (BSCH) y el Consejo Superior de Investigaciones Científicas (CSIC). El trabajo se ha enmarcado dentro de los proyectos “Máquinas Moleculares para el metabolismo de aminoácidos y de pirimidinas: estructura, función, control, arquitectura, patología y organización génica.” (BFU2004-05159) y “Complejos macromoleculares, proteínas multifuncionales, pluriempleo y enfermedades raras en la familia aminoácido quinasa” (BFU2008-05021) financiados por el Ministerio de Ciencia e Innovación. El interés del grup…
Lifestyle and Empowerment Techniques in Survivorship of Gynaecologic Oncology (LETSGO study): A study protocol for a multicentre longitudinal interve…
2021
IntroductionThe number of gynaecological cancer survivors is increasing and there is a need for a more sustainable model of follow-up care. Today’s follow-up model is time-consuming and patients have reported unmet needs regarding information about their cancer and strategies for managing the consequences of treatment. The main aim of this study is to assess health-related empowerment—in terms of patient education, psychosocial support, and promotion of physical activity—in a new follow-up model by comparing it to standard follow-up in a quasi-randomised study involving intervention hospitals and control hospitals.Methods and analysisAt the intervention hospitals, patients will be stratifie…
Single Event Upsets Induced by Direct Ionization from Low-Energy Protons in Floating Gate Cells
2017
Floating gate cells in advanced NAND Flash memories, with single-level and multi-level cell architecture, were exposed to low-energy proton beams. The first experimental evidence of single event upsets by proton direct ionization in floating gate cells is reported. The dependence of the error rate versus proton energy is analyzed in a wide energy range. Proton direct ionization events are studied and energy loss in the overlayers is discussed. The threshold LET for floating gate errors in multi-level and single-level cell devices is modeled and technology scaling trends are analyzed, also discussing the impact of the particle track size. peerReviewed
Mid-term and late results of endovascular treatment for symptomatic carotid artery stenosis under proximal protection
2021
Introduction: Although filters are still preferred during carotid stenting, proximal protection systems (PPS) are increasingly used during these procedures. PPS seem to be safer than distal systems, especially in symptomatic patients, but evidence supporting their use is limited. Aim: This was a post hoc survey with 30-day mid-term and long-term follow up, which was aimed at assessment of the safety and efficacy of stenting of the internal carotid artery under PPS in symptomatic patients. Material and methods: We analysed the results of stenting in 120 symptomatic patients presenting with at least 60% stenosis. Patients were aged 67.9 ±9.8 years, and 12 patients were older than 80 years. An…
Guessing Meaning From Word Sounds of Unfamiliar Languages: A Cross-Cultural Sound Symbolism Study
2019
Sound symbolism refers to a non-arbitrary relationship between the sound of a word and its meaning. With the aim to better investigate this relationship by using natural languages, in the present cross-linguistic study 215 Italian and Polish participants were asked to listen to words pronounced in 4 unknown non-indo-European languages (Finnish, Japanese, Swahili, Tamil) and to try to guess the correct meaning of each word, by choosing among 3 alternatives visualized on a computer screen. The alternatives were presented in the mother tongue of participants. Three different word categories were presented: nouns, verbs and adjectives. A first overall analysis confirmed a semantic role of sound…
Multidimensional instruments with an integral approach to identify frailty in community-dwelling people: protocol for a systematic psychometric review
2019
IntroductionAn increasing number of investigations highlight the complex nature of frailty; therefore, the use of multidimensional assessment instruments could be useful in clinical decision-making. Frail people are found mainly in the community setting which is why this is the ideal environment for early screening and intervention. For this purpose, it is necessary to have valid, time-effective and easy-to-use frailty assessment instruments. The aim of this review is to critically appraise, compare and summarise the quality of the measurement properties of all multidimensional instruments with an integral approach to identify frailty in community-dwelling people.Methods and analysisMedline…
Transcultural Adaptation and Theoretical Models of Validation of the Spanish Version of the Self-Care of Heart Failure Index Version 6.2 (SCHFI v.6.2)
2021
Background: Heart failure (HF) is a major and growing public health problem worldwide. Across the world, heart failure is associated with high mortality, high hospitalization rates, and poor quality of life. Self-care is defined as a naturalistic decision-making process involving the choice of behaviors that maintain physiologic stability, the response to symptoms when they occur, and the ability to follow the treatment regimen and control symptoms. One instrument used to measure self-care is the Self Care of Heart Failure Index. Aim: The purpose of this study was to test the psychometric properties of the Spanish version of the Self Care of Heart Failure Index v.6.2 (SCHFI v.6.2). Methodol…
The Scales of Psychological Well-Being – a validation, usability and test–retest study among community-dwelling older people in Finland
2020
Objectives: To validate the Finnish version of the 42-item Scales of Psychological Well-Being among community-dwelling older people. The study also examined the test–retest reliability and usability, i.e. user experience, of the scales in this age group. Method: The 42-item version of the SPWB was administered as part of a face-to-face interview among 968 men and women aged 75, 80 or 85 years. The subsample for test–retest analyses comprised 42 participants, who in addition to 11 interviewers also answered questions concerning the usability of the scales. Exploratory and confirmatory factor analyses, Cronbach’s alpha coefficients, Pearson and intra-class correlation coefficients, and Kendal…
Do the Mega and Titan Tests Yield Accurate Results? An Investigation into Two Experimental Intelligence Tests
2020
The Mega and Titan Tests were designed by Ronald K. Hoeflin to make fine distinctions in the intellectual stratosphere. The Mega Test purported to measure above-average adult IQ up to and including scores with a rarity of one in a million of the general population. The Titan Test was billed as being even more difficult than the Mega Test. In this article, these claims are subjected to scrutiny. Both tests are renormed using the normal curve of distribution. It is found that the Mega Test has a higher ceiling and a lower floor than the Titan Test. While the Mega Test may thus seem preferable as a psychometric instrument, it is somewhat marred by a number of easy items in its verbal section. …
An Immersive Motor Protocol for Frailty Rehabilitation
2019
Frailty is a pre-clinical condition that worsens physical health and quality of life. One of the most frequent symptoms of frailty is an increased risk of falling. In order to reduce this risk, we propose an innovative virtual reality motor rehabilitation program based on an immersive tool. All exercises will take place in the CAVE, a four-screen room with a stationary bike. The protocol will include two types of exercises for the improvement of balance: “Positive Bike” and “Avoid the Rocks.” We will choose evaluation scales related to the functional aspects and subjective perception of balance. Our aim is to prove that our innovative motor rehabilitation protocol is as effective as or more…