Search results for "35"

Management of biological therapies for chronic plaque psoriasis during COVID-19 emergency in Italy

2020

The coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, is creating an unprecedented global public health emergency with the continuous growth of infected individuals worldwide. Italy was one of the first European country to face the first wave of infection outside mainland China. The first case of COVID-19 was confirmed in Lombardy on February 20th , 2020, and subsequently, a rapid increase in the number of detected cases was observed, spreading through Italy and the rest of Europe.3 As of April 22nd , confirmed COVID-19 cases in Italy were 183,957.

Interocular differences in visual quality due to ocular aberrations and scattering in a patient with post-traumatic anisocoria: A case report

2012

AbstractA 41-year-old patient with visual disturbances after an ocular trauma in right eye three years before was carefully analyzed and discussed. No corneal or intraocular sequelae were present. Only a significant anisocoria could be observed. Right eye (RE) achieved a best spectacle-corrected visual acuity (BSCVA) of 0.05 LogMAR with a refraction of +0.50 sphere and −1.25 cylinder. Left eye (LE) achieved a BSCVA of 0.0 LogMAR with a refraction of +0.75 sphere and −1.00 cylinder. In photopic conditions pupil diameter was 4.96mm for RE and 3.02mm for LE whereas in scotopic conditions, these values were 7.45mm and 6.71mm, respectively. More significant levels of higher-order corneal and ocu…

Evidence for a 'window of opportunity' in hidradenitis suppurativa treated with adalimumab: a retrospective, real-life multicentre cohort study

2021

BACKGROUND The anti-tumour necrosis factor (TNF)-α adalimumab is the only licenced biologic for moderate-to-severe hidradenitis suppurativa (HS). No predictors of response have been identified so far. OBJECTIVES To identify clinical parameters predicting response to adalimumab and confirm its efficacy/safety. METHODS The data of 389 patients with HS treated with adalimumab in 21 Italian centres were reviewed. Sex, age at onset/diagnosis/baseline, body mass index, smoking, phenotype, previous treatments, concomitant antibiotics and 'therapeutic delay', defined as the time from HS onset to adalimumab initiation, were assessed. Response to adalimumab and its impact on quality of life (QoL) wer…

Cutaneous Adverse Reactions to Highly Antiretroviral Therapy in HIV-Positive Patients

2013

Adverse drug reactions to highly antiretroviral therapy (HAART) are major obstacles in its success. Although overall mortality from HIV has dramatically declined owing to HAART, these antiretroviral regimens have been associated with a wide spectrum of severe cutaneous reactions. The severity of cutaneous adverse reactions varies greatly, and some may be difficult to manage. To optimize adherence and efficacy of antiretroviral treatment, clinicians must focus on preventing adverse effects whenever possible, and distinguish those that are self-limited from those that are potentially serious. This paper presents the case of a serious cutaneous adverse reaction to Atripla in a HIV-positive 50-…

Pseudochromhidrosis: the role of dermoscopy in diagnosis

2014

The Right to Education and ICT during COVID-19: An International Perspective

2020

There is a lack of concluding evidence among epidemiologists and public health specialists about how school closures reduce the spread of COVID-19. Herein, we attend to the generalization of this action throughout the world, specifically in its quest to reduce mortality and avoid infections. Considering the impact on the right to education from a global perspective, this article discusses how COVID-19 has exacerbated inequalities and pre-existing problems in education systems around the world. Therefore, the institutional responses to guaranteeing remote continuity of the teaching&ndash

The prevalence of bipolar disorders in the general population - a growing trending topic?

2015

report the first meta-analysis of theprevalence of bipolar disorder (BD) from population-based studies. Strengths of the manuscript include theuse of suitable methods of analysis, reporting both annualand lifetime prevalence rates, and providing separatedata for bipolar subtypes I and II. The latter is relevantbecause type II is not simply a milder or minor form of BD.This publication is of considerable interest, firstlybecause it confirms that the frequency of BD in thegeneral population is low and closer to the conservativeestimates of 1-2%, as suggested by historical data.

Preliminary in vivo positional analysis of a posterior chamber phakic intraocular lens by optical coherence tomography and its correlation with clini…

2012

Purpose: To analyze by spectral-domain optical coherence tomography the anatomical relationship of a specific type of posterior chamber phakic intraocular lens (pIOL) implanted in cases of high to moderate myopia with the adjacent intraocular structures and to correlate it with clinical outcomes. Methods: Prospective observational case series including 18 eyes with high to moderate myopia (spherical equivalent between −5.88 and −15.75 D) of 9 patients (age range, 29–49 years) undergoing bilateral Phakic Refractive Lens (PRL, Zeiss) implantation. Postoperative visual acuity, refraction, contrast sensitivity (CS), and ocular higher order aberrations (HOA) were evaluated. Furthermore, the in v…

Visual Impairment Is Associated With Depressive Symptoms—Results From the Nationwide German DEGS1 Study

2018

Introduction: Visual impairment is associated with a variety of co-morbidities including physical and mental health in industrial countries. Our aim is to examine associations between self-reported impairment and depressive symptoms in the German population. Methods: The point prevalence of self-reported visual impairment in Germany was computed using data from the German Health Interview and Examination Survey for adults from 2008 to 2011 (N=7.783, 50.5% female, age range 18-79 years). Visual impairment was surveyed by two questions, one for seeing faces at a distance of 4 meters and one for reading newspapers. Depressive symptoms were evaluated with the PHQ-9 questionnaire and two-week pr…

Anterior chamber depth measurement in teenagers. Comparison of two techniques

2013

Purpose: The aim of this study is to determine the anterior chamber depth (ACD) in teenagers using two different devices: partial coherence interferometry IOLMaster (Carl Zeiss Meditec) and anterior segment optical coherence tomography (Visante TM OCT, Carl Zeiss Meditec) and to evaluate the degree of agreement between ACD measurements carried out by both instruments. Methods: In this prospective study 68 eyes of 34 emmetropic Caucasic patients (18 girls and 16 boys) were analysed. ACD was measured from the anterior corneal surface to anterior surface of the crystalline lens. For each age the ACD size was calculated and the difference between IOLMaster and Visante-OCT measurements was analy…