Search results for "38"
showing 10 items of 1730 documents
Application of EMI and FDR Sensors to Assess the Fraction of Transpirable Soil Water over an Olive Grove
2018
Accurate soil water status measurements across spatial and temporal scales are still a challenging task, specifically at intermediate spatial (0.1–10 ha) and temporal (minutes to days) scales. Consequently, a gap in knowledge limits our understanding of the reliability of the spatial measurements and its practical applicability in agricultural water management. This paper compares the cumulative EM38 (Geonics Ltd., Mississauga, ON, Canada) response collected by placing the sensor above ground with the corresponding soil water content obtained by integrating the values measured with an FDR (frequency domain reflectometry) sensor. In two field areas, characterized by different soil clay conte…
Complement Protein C1q Binds to Hyaluronic Acid in the Malignant Pleural Mesothelioma Microenvironment and Promotes Tumor Growth
2017
C1q is the first recognition subcomponent of the complement classical pathway, which acts towards the clearance of pathogens and apoptotic cells. C1q is also known to modulate a range of functions of immune and non-immune cells, including their involvement in placental development and sensorial synaptic pruning. We have recently shown that C1q can promote tumour by encouraging their adhesion, migration and proliferation in addition to angiogenesis and metastasis. In this study, we have examined the role of C1q in the microenvironment of malignant pleuric mesothelioma (MPM), a rare form of cancer commonly associated with exposure to asbestos. We found that C1q was highly expressed in all MPM…
Human γδ T-Cells: From Surface Receptors to the Therapy of High-Risk Leukemias
2018
γδ T lymphocytes are potent effector cells, capable of efficiently killing tumor and leukemia cells. Their activation is mediated by γδ T-cell receptor (TCR) and by activating receptors shared with NK cells (e.g., NKG2D and DNAM-1). γδ T-cell triggering occurs upon interaction with specific ligands, including phosphoantigens (for Vγ9Vδ2 TCR), MICA-B and UL16 binding protein (for NKG2D), and PVR and Nectin-2 (for DNAM-1). They also respond to cytokines undergoing proliferation and release of cytokines/chemokines. Although at the genomic level γδ T-cells have the potential of an extraordinary TCR diversification, in tissues they display a restricted repertoire. Recent studies have identified …
Vitamin D, allergies and asthma: focus on pediatric patients
2014
In recent years, the interest of the scientific world towards vitamin D gradually increased, and several studies have been conducted to dissect its possible role in modulating the development/course of allergic diseases. Also, Vitamin D supplementation has been assessed as a beneficial approach for treating allergies in some, but not all studies. We reviewed herein the available and relevant literature concerning the possible links between Vitamin D, its supplementation and allergic diseases. A literature search was made independently by the Authors, identifying articles for a narrative review. As per literature, Vitamin D plays a key role in calcium and phosphate metabolism, and it is esse…
Blood Transfusion Management for Patients Treated With Anti-CD38 Monoclonal Antibodies
2018
Daratumumab has proven to be highly efficacious for relapsed and refractory multiple myeloma (MM) and has recently been approved in the frontline setting for MM patients ineligible for transplantation. In the future, expanded indications are possible for daratumumab and other anti-CD38 monoclonal antibodies in development. For several years, it has been recognized that these therapies interfere with blood bank testing by binding to CD38 on red blood cells and causing panagglutination on the Indirect Antiglobulin Test. This can lead to redundant testing and significant delays in patient care. Given the anticipated increase in utilization of anti-CD38 monoclonal antibodies, as well as the tra…
Le misure di riorganizzazione del personale alle dipendenze della p.a. Tra obiettivi di efficienza ed esigenze di razionalizzazione della spesa pubbl…
2012
Riassunto- Il saggio analizza le politiche di riorganizzazione del personale alle dipendenze delle p.a., alla luce delle più recenti modifiche legislative. Secondo le più recenti analisi statistiche, la Pubblica Amministrazione italiana registra, a livello strutturale, numerose inefficienze correlate all’irrazionale distribuzione delle risorse umane. Per ovviare a dette disfunzioni, il legislatore è intervenuto a più riprese sul quadro normativo in materia di mobilità, modificando sia la disciplina degli strumenti di programmazione e gestione delle risorse umane (passaggi diretti di personale, trasferimenti, comandi, distacchi e assegnazioni temporanee), sia i meccanismi regolativi per il …
Flexicurity as a measuring leakage protection of workers: between "social pollution" and "total security"
2012
Was not the labour problem the same everywhere? The paper attempts to answer this question by proposing a re-interpretation of flexicurity through the comparison with the economic concepts of externalities and distortion of competition. After a methodological and epistemological premise, based on a multidisciplinary literature, the paper - critically addresses the origins of flexicurity and argues that it lacks an archetypical definition, especially in the formulation of the EU Commission. Hence, the paper considers flexicurity as any balance between flexibility and security and, therefore, proposes ordering any set of contracts, providing the same balance and with the same regulatory fr…
Sul nuovo rito dei licenziamenti e una proposta di modifica
2012
Lo studio propone una prima analisi delle norme che regolano il c.d. nuovo rito dei licenziamenti, introdotto dalla riforma Fornero, come complemento alla modificazione disciplina della reintegrazione e dei licenziamenti collettivi, allo scopo di snellire e accelerare i processi in questa materia e di aumentare la certezza in ordine alla risoluzione dei rapporti. Chiude lo studio un'appendice in cui l'autore propone un modello alternativo di rito dei licenziamenti.The study provides an initial analysis of the rules of the new trial of dismissals. It introduced by the Fornero reform, as a complement to the modification both dismissal reinstatement and collective redundancies. The purpos…
Liberalizzazione e flessibilità del mercato del lavoro marittimo: le agenzie di lavoro e l’arruolamento dell’equipaggio
2010
Lo studio affronta il tema della somministrazione di lavoro in ambito marittimo.
La tutela del credito nel diritto del lavoro (pignorabilità e compensabilità)
2010
Questo studio, dopo la ricostruzione della disciplina della pignorabilità e compensabilità dei crediti del lavoratore, analizza criticamente l'istituto della compensazione atecnica e ne propone una rilettura coerente con la struttura della fattispecie e la ragione d'essere dei limiti alla compensazione. This study, after the reconstruction of the discipline of the distrainteness and of the countervailability of the credit of the employee, critically analyses the institution of latu sensu countervailability and eventually proposes a new reading consistent with the structure of the case and the raison d'etre for legal limits for the employee's credits' countervailability.