Search results for "38"
showing 10 items of 1730 documents
Inter- and intracellular signaling in amyotrophic lateral sclerosis: role of p38 mitogen-activated protein kinase.
2006
The pathogenetic processes underlying the selective motor neuron degeneration in amyotrophic lateral sclerosis (ALS) are complex and still not completely understood even in the cases of inherited disease caused by mutations in the Cu/Zn superoxide dismutase-dependent (SOD1) gene. Recent evidence supports the view that ALS is not a cell-autonomous disease and that glial-neuron cross-talk, throughout cytokines and other toxic factors like the nitric oxide and superoxide, is a crucial determinant for the induction of motor neuron death. This cell-cell interaction may determine the progression of the disease through processes that are likely independent of the initial trigger and that may conve…
Influences on mutual fund performance: comparing US and Europe using qualitative comparative analysis
2019
This study examines the conditions that lead mutual funds to underperform or outperform competitors. Using fuzzy-set qualitative comparative analysis (fsQCA), we draw upon extensive research on fund returns to affirm and extend earlier discoveries. Fund performance (Morningstar ratings), features of the funds themselves, and characteristics of the fund managers are considered. Positive Morningstar star and analyst ratings are necessary conditions for funds to generate value (measured by Jensen’s alpha). Funds with low management fees and low ongoing fees have attractive Sharpe ratios and high returns. Likewise, large funds with good Morningstar ratings have good Sharpe ratios and returns, o…
Road Traffic Pollution and Childhood Leukemia: A Nationwide Case-control Study in Italy
2016
Background The association of childhood leukemia with traffic pollution was considered in a number of studies from 1989 onwards, with results not entirely consistent and little information regarding subtypes. Aim of the study We used the data of the Italian SETIL case-control on childhood leukemia to explore the risk by leukemia subtypes associated to exposure to vehicular traffic. Methods We included in the analyses 648 cases of childhood leukemia (565 Acute lymphoblastic–ALL and 80 Acute non lymphoblastic-AnLL) and 980 controls. Information on traffic exposure was collected from questionnaire interviews and from the geocoding of house addresses, for all periods of life of the children. Re…
CCDC 938974: Experimental Crystal Structure Determination
2014
Related Article: Lena Kaufmann, Nora L. Traulsen, Andreas Springer, Hendrik V. Schröder, Toni Mäkelä, Kari Rissanen, Christoph A. Schalley|2014|Org.Chem.Front.|1|521|doi:10.1039/C4QO00077C
Strong absorption and ultrafast localisation in NaBiS2 nanocrystals with slow charge-carrier recombination.
2022
Funder: AiF Project, no: ZIM-KK5085302DF0
Trattamento della Nefrite Lupica in età pediatrica: dalla clinical practice alla letteratura
2021
L-selectin regulates human neutrophil transendothelial migration
2021
ABSTRACT The migration of circulating neutrophils towards damaged or infected tissue is absolutely critical to the inflammatory response. L-selectin is a cell adhesion molecule abundantly expressed on circulating neutrophils. For over two decades, neutrophil L-selectin has been assigned the exclusive role of supporting tethering and rolling – the initial stages of the multi-step adhesion cascade. Here, we provide direct evidence for L-selectin contributing to neutrophil transendothelial migration (TEM). We show that L-selectin co-clusters with PECAM-1 – a well-characterised cell adhesion molecule involved in regulating neutrophil TEM. This co-clustering behaviour occurs specifically during …
"Table 1" of "Electromagnetic fission of U-238 at 600-MeV and 1000-MeV per nucleon"
1997
Electromagnetic fission.
Heavy-antiquark–diquark symmetry and heavy hadron molecules: Are there triply heavy pentaquarks?
2013
We explore the consequences of heavy flavor, heavy quark spin, and heavy antiquark-diquark symmetries for hadronic molecules within an effective field theory framework. Owing to heavy antiquark-diquark symmetry, the doubly heavy baryons have approximately the same light-quark structure as the heavy antimesons. As a consequence, the existence of a heavy meson-antimeson molecule implies the possibility of a partner composed of a heavy meson and a doubly heavy baryon. In this regard, the D (D) over bar* molecular nature of the X(3872) will hint at the existence of several baryonic partners with isospin I = 0 and J(P) = 5(-)/2 or 3(-)/2. Moreover, if the Z(b)(10650) turns out to be a B*(B) over…
Nature of the light scalar mesons
2005
Despite the apparent simplicity of meson spectroscopy, light scalar mesons cannot be accommodated in the usual $q\bar q$ structure. We study the description of the scalar mesons below 2 GeV in terms of the mixing of a chiral nonet of tetraquarks with conventional $q\bar q$ states. A strong diquark-antidiquark component is found for several states. The consideration of a glueball as dictated by quenched lattice QCD drives a coherent picture of the isoscalar mesons.