Search results for "3rd-DAS"
showing 10 items of 22 documents
Hydrogen non-equilibrium ionisation effects in coronal mass ejections
2020
This research has received funding from the Science and Technology Facilities Council (UK) through the consolidated grant ST/N000609/1 and the European Research Council (ERC) under the European Union Horizon 2020 research and innovation program (grant agreement No. 647214). D.H.M. would like to thank both the UK STFC and the ERC (Synergy grant: WHOLE SUN, grant Agreement No. 810218) for financial support. D.H.M. and P.P. would like to thank STFC for IAA funding under grant number SMC1-XAS012. This work used the DiRAC@Durham facility man-aged by the Institute for Computational Cosmology on behalf of the STFC DiRAC HPC Facility (www.dirac.ac.uk. The equipment was funded by BEIS capital fundin…
Determining the source and eruption dynamics of a stealth CME using NLFFF modelling and MHD simulations
2021
Coronal mass ejections (CMEs) that exhibit weak or no eruption signatures in the low corona, known as stealth CMEs, are problematic as upon arrival at Earth they can lead to geomagnetic disturbances that were not predicted by space weather forecasters. We investigate the origin and eruption of a stealth event that occurred on 2015 January 3 that was responsible for a strong geomagnetic storm upon its arrival at Earth. To simulate the coronal magnetic field and plasma parameters of the eruption we use a coupled approach. This approach combines an evolutionary nonlinear force-free field model of the global corona with a MHD simulation. The combined simulation approach accurately reproduces th…
Adolescent transport and unintentional injuries: a systematic analysis using the Global Burden of Disease Study 2019
2022
Correction to Lancet Public Health 2022; 7: e657-69. Lancet Public Health. 2022 Dec;7(12):e992. doi: 10.1016/S2468-2667(22)00294-8. PMID: 36462522. Background: Globally, transport and unintentional injuries persist as leading preventable causes of mortality and morbidity for adolescents. We sought to report comprehensive trends in injury-related mortality and morbidity for adolescents aged 10-24 years during the past three decades. Methods: Using the Global Burden of Disease, Injuries, and Risk Factors 2019 Study, we analysed mortality and disability-adjusted life-years (DALYs) attributed to transport and unintentional injuries for adolescents in 204 countries. Burden is reported in absolut…
The global burden of cancer attributable to risk factors, 2010–19 : A systematic analysis for the Global Burden of Disease Study 2019
2022
Background: Understanding the magnitude of cancer burden attributable to potentially modifiable risk factors is crucial for development of effective prevention and mitigation strategies. We analysed results from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019 to inform cancer control planning efforts globally. Methods: The GBD 2019 comparative risk assessment framework was used to estimate cancer burden attributable to behavioural, environmental and occupational, and metabolic risk factors. A total of 82 risk-outcome pairs were included on the basis of the World Cancer Research Fund criteria. Estimated cancer deaths and disability-adjusted life-years (DALYs) in 20…
Trends in Adolescent Overweight Perception and Its Association With Psychosomatic Health 2002–2014 : Evidence From 33 Countries
2017
Purpose Perceiving oneself as overweight is common and strongly associated with adolescents' subjective well-being. The prevalence of overweight perceptions and their impact on well-being may have increased over the past decade due to an increase in the salience of weight-related issues. This study examines trends (2002–2014) in the prevalence of adolescent overweight perceptions and their association with psychosomatic complaints. Methods Data from 15-year-old adolescents were obtained between 2002 and 2014 in four rounds of the Health Behaviour in School-aged Children study in 33 countries in Europe and North America (N = 187,511). Design-adjusted logistic regressions were used to quantif…
Burden of non-communicable diseases among adolescents aged 10-24 years in the EU, 1990-2019: a systematic analysis of the Global Burden of Diseases S…
2022
Background: Disability and mortality burden of non-communicable diseases (NCDs) have risen worldwide; however, the NCD burden among adolescents remains poorly described in the EU. Methods: Estimates were retrieved from the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) 2019. Causes of NCDs were analysed at three different levels of the GBD 2019 hierarchy, for which mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life-years (DALYs) were extracted. Estimates, with the 95% uncertainty intervals (UI), were retrieved for EU Member States from 1990 to 2019, three age subgroups (10–14 years, 15–19 years, and 20–…
Pan-cancer analysis of whole genomes
2020
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Psychiatric genome-wide association study analyses implicate neuronal, immune and histone pathways
2015
G.B. and S.N. acknowledge funding support for this work from the National Institute for Health Research (NIHR) Mental Health Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London. P.H.L. is supported by US National Institute of Mental Health (NIMH) grant K99MH101367. Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple genetic associations with such disorders, but better methods are needed to derive the underlying biological mechanisms that these signals indicate. We sought to identify biological pathways in GWAS data from over 60,000 participants from the Psychiatric Genomics Consortium. We developed an an…
Revising midlatitude summer temperatures back to A.D. 600 based on a wood density network
2015
Annually resolved and millennium-long reconstructions of large-scale temperature variability are primarily composed of tree ring width (TRW) chronologies. Changes in ring width, however, have recently been shown to bias the ratio between low- and high-frequency signals. To overcome limitations in capturing the full spectrum of past temperature variability, we present a network of 15 maximum latewood density (MXD) chronologies distributed across the Northern Hemisphere extratropics. Independent subsets of continental-scale records consistently reveal high MXD before 1580 and after 1910, with below average values between these periods. Reconstructed extratropical summer temperatures reflect n…
The era of reference genomes in conservation genomics
2022
Progress in genome sequencing now enables the large-scale generation of reference genomes. Various international initiatives aim to generate reference genomes representing global biodiversity. These genomes provide unique insights into genomic diversity and architecture, thereby enabling comprehensive analyses of population and functional genomics, and are expected to revolutionize conservation genomics.