Search results for "4-D"
showing 10 items of 955 documents
CCDC 915981: Experimental Crystal Structure Determination
2014
Related Article: Inguna Goba, Baiba Turovska, Sergey Belyakov, Edvards Liepinsh|2014|J.Mol.Struct.|1074|549|doi:10.1016/j.molstruc.2014.06.044
CCDC 907992: Experimental Crystal Structure Determination
2014
Related Article: Inguna Goba, Baiba Turovska, Sergey Belyakov, Edvards Liepinsh|2014|J.Mol.Struct.|1074|549|doi:10.1016/j.molstruc.2014.06.044
CCDC 885313: Experimental Crystal Structure Determination
2013
Related Article: I.Goba,B.Turovska,S.Belyakov,E.Liepinsh|2013|Khim.Get.Soedin.,SSSR||778|
1,4 - dihidropiridīna atvasinājumu (AV-153-sāļu) mijiedarbības izpēte pret c-Myc antiparalēlo kvadrupleksu, izmantojot UV/redzamo spektroskopiju
2020
Pedējos gados ievērojami pastiprinājusies uzmanība pret DNS guanīna kvadrupleksiem un to lomu onkoģenēzē. c-Myc proto-onkogēna pastiprināta ekspresija ir saistīta ar dažādiem cilvēka audzējiem, ka arī ar slikto prognozi. Līdz ar to DNS guanīna kvadrupleksu veidošana un stabilizācija C-myc promoter reģionos ir kritiska c-Myc trankripcijas inhibēšanai, tāpēc pēdējos gados aktīvi tiek meklēti savienojumi, kuri var stabilizēt G-kvadrupleksu struktūras un inhibēt c-Myc gēna ekspresiju. Šī pētījuma darba mērķis bija izpētīt 1,4-dihidropiridīna atvasinājumu (AV-153 sāļu un to analoga AV-154-Na sāls) spēju mijiedarboties ar antiparalēlo c-myc kvadrupleksu, kā arī spēju mijiedarboties ar vienpavadie…
Pyrazolo[3,4-d]pyrimidine derivatives as COX-2 selective inhibitors: synthesis and molecular modelling studies.
2009
The pyrazolo[3,4-d]pyrimidine system shows a multitude of interesting pharmacological properties. Owing to the potential anti-inflammatory activity of 5-benzamido-pyrazolo[3,4-d]pyrimidin- 4-one derivatives and considering the easy synthesis of this class of compounds, a set of new 5- benzamido-1H-pyrazolo[3,4-d]pyrimidin-4-ones has been prepared in 42-80% yields by reacting 5- aminopyrazole-4(N-benzoyl)carbohydrazide derivatives and the opportune triethylorthoesters. Compounds 8a, b, 10a–d, and 11a, b revealed a superior inhibitory profile against COX-2, when compared to that of reference standards NS398 and indomethacin. Molecular modelling studies confirmed the obtained biological result…
Analysis of pecan nut ([i]Carya illinoinensis[/i]) unsaponifiable fraction. Effect of ripening stage on phytosterols and phytostanols composition
2014
Changes in 4-desmethylsterol, 4-monomethylsterol, 4,4-dimethylsterol and phytostanol composition were quantitatively and qualitatively investigated during the ripening of three varieties of Tunisian-grown pecan nuts (Mahan, Moore and Burkett). These components have many health benefits, especially in lowering LDL-cholesterol and preventing heart disease. The phytosterol composition of whole pecan kernel was quantified by Gas Chromatography-Flame Ionisation Detection (GC-FID) and identified by Gas Chromatography-Mass Spectrometry (GC-MS). Fifteen phytosterols and one phytostanol were quantified. The greatest amount of phytosterols (2852.5 mg/100 g of oil) was detected in Mahan variety at 20 …
Effect of 2,4-Diacetylphloroglucinol on Pithium : cellular responses and variation in sensitivity among propagules and species
2003
International audience
Comparison of methods to estimate LAI from remote sensing in maize canopies by inversion of 1-D and 3-D models
2009
The inversion of canopy reflectance models is a procedure widely employed for the retrieval of LAI from remote sensing. However the accuracy of the estimates depends on a range of factors, most notably the realism of the canopy representation of the models employed and the a priori knowledge of some vegetation characteristics. The objective of the present work was to compare the performances and the operational limitations of the use of two contrasting type of radiative transfer models: a classical one-dimensional canopy reflectance model, PROSPECT+SAIL (PROSAIL) and a three-dimensional dynamic maize model (Lopez-Lozano et al., 2007) having greater realism in the description of the canopy s…
Chemical transformations of glucose in solutions for peritoneal dialysis after sterilization and during storage
2018
The objective of this work was to estimate glucose degradation products (GDPs) in solutions for peritoneal dialysis (PD) including glucose and sodium lactate based on the change of pH and absorption of ultraviolet (UV) light. Spectrophotometric and pH-metric methods were used to measure glucose degradation and transformation of GDPs in laboratory-made solutions after heat sterilization and during storage. Mechanism of transformations of GDPs in the sterilized solutions for PD during storage and spectral characteristic of 5-HMF were studied. Common features for all the batches of the tested solutions for PD after heat sterilization were a reduce in pH, increase in the absorbance in the range…
Synthesis and anti-staphylococcal activity of new 4-diazopyrazole derivatives.
2012
Abstract Several new 4-diazopyrazole derivatives 6a – g and 9a – c were obtained by the reaction of 1-(R-substituted-phenyl)-3-(1,3-dimethyl-1 H -pyrazol-5-yl)ureas 5a – g and N -(1,3-dimethyl-1 H -pyrazol-5-yl)-2-(R-substituted-phenyl)acetamides 8a – c respectively with a sevenfold excess of nitrous acid in acetic acid solution. The compounds were assayed for their activity against the Staphylococcus aureus reference strains ATCC 25923, ATCC 29213 and ATCC 6538, as well as six veterinary strains. The best anti-staphylococcal profile was showed by [(R-substituted-phenyl)acetyl](4-diazonio-1,3-dimethyl-1 H -pyrazol-5-yl)azanides 9a , c . Compound 9c was also able at 3.1 μg mL −1 to inhibit o…