Search results for "4-D"
showing 10 items of 955 documents
Monokatjonu un dikatjonu jonu šķidrumu izmantošana C-C saites veidošanas reakcijās
2015
Elektroniskā versija nesatur pielikumus
Identification of a third secondary carrier (DcuC) for anaerobic C4-dicarboxylate transport in Escherichia coli: roles of the three Dcu carriers in u…
1996
In Escherichia coli, two carriers (DcuA and DcuB) for the transport of C4 dicarboxylates in anaerobic growth were known. Here a novel gene dcuC was identified encoding a secondary carrier (DcuC) for C4 dicarboxylates which is functional in anaerobic growth. The dcuC gene is located at min 14.1 of the E. coli map in the counterclockwise orientation. The dcuC gene combines two open reading frames found in other strains of E. coli K-12. The gene product (DcuC) is responsible for the transport of C4 dicarboxylates in DcuA-DcuB-deficient cells. The triple mutant (dcuA dcuB dcuC) is completely devoid of C4-dicarboxylate transport (exchange and uptake) during anaerobic growth, and the bacteria are…
CCDC 210702: Experimental Crystal Structure Determination
2003
Related Article: C.Capacchione, A.Proto, H.Ebeling, R.Mulhaupt, K.Moller, T.P.Spaniol, J.Okuda|2003|J.Am.Chem.Soc.|125|4964|doi:10.1021/ja029968g
CCDC 104283: Experimental Crystal Structure Determination
1997
Related Article: J.Ratilainen, K.Airola, M.Nieger, M.Bohme, J.Huuskonen, K.Rissanen|1997|Chem.-Eur.J.|3|749|doi:10.1002/chem.19970030515
The overproduction of 2,4-DTBP accompanying to the lack of available form of phosphorus during the biodegradative utilization of aminophosphonates by…
2014
Although information about the ability of some filamentous fungi to biodegrade organophosphonates is available, the knowledge about accompanying changes in fungal metabolism is very limited. The aim of our study was to determine the utilization of the chosen, structurally diverse aminophosphonates by Aspergillus terreus (Thom), in the context of the behaviour of this fungus while growing in unfavourable conditions, namely the lack of easily available phosphates. We found that all the studied compounds were utilized by fungus as nutritive sources of phosphorus, however, their effect on the production of fungal biomass depended on their structure. We also observed an interesting change in the…
Design of pharmacophoric group containing 1,4-dihydropyridine derivatives and determination of spectrum of pharmacological activities
2017
Vairākkārtīgi ir uzsvērts, ka 1,4-dihidropiridīna cikls ir viens no farmakoloģiski priviliģētām struktūrām, kas iedarbojas uz jonu kanāliem un dažādiem receptoriem, un kuru modificējot, sintezējot tās struktūras analogus, variējot aizvietotājus molekulā, būtu iespējams iegūt dažādus farmakoloģiski aktīvus savienojumus. Pētījumā ir sintezēti jauni, mērķtiecīgi dizainēti, farmakoforas grupas saturoši 1,4-dihidropiridīna atvasinājumi, sistemātiski mainot farmakoforās grupas (piridīniju un/vai propargil) un to atrašanās vietu molekulā. Izvērtēts sintezēto savienojumu farmakoloģiskās darbības spektrs (aktivitāte uz kalcija kanāliem, antiradikālā aktivitāte un reducējošā kapacitāte), veidots stru…
1,4 - dihidropiridīnu iedarbība uz DNS struktūru
2015
Bakalaura darba mērķis bija izpētīt deviņu 1,4-DHP atvasinājumu (alapirons, AV-153-Ca, AV-153-Mg, AV-153-Rb, etkarbatons, J-6-138, nimodipīns, nitrendipīns, PP-501) spēju pasargāt plazmīdas pTZ57R DNS struktūru hidroksilradikāla klātbūtnē, kas tika radīts ar Fentona reakcijas palīdzību in vitro. Šo īpašību izvērtēšanai, izmantojām horizontālo gēla elektroforēzes metodi. AV-153-Ca, AV-153-Mg un nitrendipīns uzrāda visizteiktākās plazmīdas DNS pasargājošās īpašības.
Evaluation of Physicochemical Properties of Amphiphilic 1,4-Dihydropyridines and Preparation of Magnetoliposomes
2021
This study was focused on the estimation of the targeted modification of 1,4-DHP core with (1) different alkyl chain lengths at 3,5-ester moieties of 1,4-DHP (C12, C14 and C16)
Synthesis and X-ray Crystal Structure of New Substituted 3-4′-Bipyrazole Derivatives. Hirshfeld Analysis, DFT and NBO Studies
2021
A new compounds named 3-4′-bipyrazoles 2 and 3 were synthesized in high chemical yield from a reaction of pyran-2,4-diketone 1 with aryl hydrazines under thermal conditions in MeOH. Compound 2 was unambiguously confirmed by single-crystal X-ray analysis. It crystalizes in a triclinic crystal system and space group P-1. Its crystal structure was found to be in good agreement with the spectral characterizations. With the aid of Hirshfeld calculations, the H…H (54.8–55.3%) and H…C (28.3–29.2%) intermolecular contacts are the most dominant, while the O…H (5.8–6.5%), N…H (3.8–4.6%) and C…C (3.0–4.9%) are less dominant. The compound has a polar nature with a net dipole moment of 6.388 Debye. The …
pcaH, a molecular marker for estimating the diversity of the protocatechuate-degrading bacterial community in the soil environment
2007
Microorganisms degrading phenolic compounds play an important role in soil carbon cycling as well as in pesticide degradation. The pcaH gene encoding a key ring-cleaving enzyme of the -ketoadipate pathway was selected as a functional marker. Using a degenerate primer pair, pcaH fragments were cloned from two agricultural soils. Restriction fragment length polymorphism (RFLP) screening of 150 pcaH clones yielded 68 RFLP families. Comparison of 86 deduced amino acid sequences displayed 70% identity to known PcaH sequences. Phylogenetic analysis results in two major groups mainly related to PcaH sequences from Actinobacteria and Proteobacteria phyla. This confirms that the developed primer pai…