Search results for "40"

Increasing concentration of polyunsaturated fatty acids in browning boreal lakes is driven by nuisance algaGonyostomum

2020

Elevated concentrations of dissolved organic carbon (DOC) promote browning of lakes, which alters the physicochemical properties of water and ecosystem functioning. However, browning‐induced changes in basal production of polyunsaturated fatty acids from the n‐3 and n‐6 families (n‐3 and n‐6 PUFA) in lakes are not fully understood. The concentrations of PUFA, which are micronutrients required to maintain growth and reproduction of consumers, have been suggested to either rise or decline in seston as a response to lake browning. Elevated DOC concentrations may also promote bacterial biomass and production and thus potentially increase the concentration of bacterial fatty acids (BAFA) in sest…

Dicyclopentaannelated Hexa-peri-hexabenzocoronenes with a Singlet Biradical Ground State

2021

Abstract Synthesis of two dicyclopentaannelated hexa‐peri‐hexabenzocoronene (PHBC) regioisomers was carried out, using nonplanar oligoaryl precursors with fluorenyl groups: mPHBC 8 with two pentagons in the “meta”‐configuration was obtained as a stable molecule, while its structural isomer with the “para”‐configuration, pPHBC 16, could be generated and characterized only in situ due to its high chemical reactivity. Both PHBCs exhibit low energy gaps, as reflected by UV‐vis‐NIR absorption and electrochemical measurements. They also show open‐shell singlet ground states according to electron paramagnetic resonance (EPR) measurements and density functional theory (DFT) calculations. The use of…

Removal of molecular contamination in low-energy RIBs by the isolation-dissociation-isolation method

2020

Nuclear instruments & methods in physics research / B 463, 324 - 326 (2020). doi:10.1016/j.nimb.2019.04.072

Separation of atomic and molecular ions by ion mobility with an RF carpet

2021

Gas-filled stopping cells are used at accelerator laboratories for the thermalization of high-energy radioactive ion beams. Common challenges of many stopping cells are a high molecular background of extracted ions and limitations of extraction efficiency due to space-charge effects. At the FRS Ion Catcher at GSI, a new technique for removal of ionized molecules prior to their extraction out of the stopping cell has been developed. This technique utilizes the RF carpet for the separation of atomic ions from molecular contaminant ions through their difference in ion mobility. Results from the successful implementation and test during an experiment with a 600~MeV/u $^{124}$Xe primary beam are…

Valoración del cumplimiento de un programa de escuela de espalda vs el tratamiento farmacológico en la lumbalgia crónica

2015

Introducción y Objetivos: La Escuela de Espalda es una alternativa terapéutica y de prevención secundaria en el tratamiento de la lumbalgia crónica que pretende entre otras hacer al paciente conocedor de su patología, que adquiera hábitos saludables e implicarle en su manejo y cuidados, Así mismo es bien conocida la dificultad para que los pacientes cumplan con los tratamientos y recomendaciones que el médico les prescribe, por lo que en la presente Tesis Doctoral se proponen los siguientes objetivos: 1. Valorar el grado de cumplimiento de la Escuela de Espalda (EE) utilizada como estrategia terapéutica en pacientes con dolor lumbar crónico. 2. Valorar el grado de cumplimiento del tratamien…

Emblemi del Novecento. Cruciverba, linguaggio, luoghi comuni: faccette di storia culturale del Moderno

2009

Taivaan tsaaritar? Valamon luostarin pääkirkon ikonostaasin Jumalanäidin ikoni

2016

Artikkelissani keskityn analysoimaan aikaisemmin Laatokalla mutta nykyisin Uudessa Valamossa Heinävedellä olevaa Jumalanäiti valtaistuimella -ikonia historiallisessa kontekstissa, jonka pääpaino on 1890–1920-luvuilla, jolloin se samoin kuin muut uuden pääkirkon (valmistui vuonna 1896) ikonostaasiin maalatut kuvat olivat uusia. Ikonien ja maallisen vallan problematiikka tiivistyy kysymykseksi, voidaanko kookkaan, vasta maalatuista ikoneista koostuvaan kuvaseinään sisältyneen teoksen tulkita ilmentäneen Romanovien hallitusta syntyaikanaan vuosisadan taitteessa ja alussa, tai sen jälkeen, kun keisarivalta päättyi ja Jumalanäiti valtaistuimella jäi Suomen tasavaltaan kuuluneeseen Karjalan osaan…

When the Grafting of Double Decker Phthalocyanines on Si(100)-2 × 1 Partly Affects the Molecular Electronic Structure

2016

International audience; A combined X-ray photoelectron spectroscopy (XPS), scanning tunneling microscopy (STM), and density functional theory (DFT) study has been performed to characterize the adsorbate interaction of lutetium biphthalocyanine (LuPc2) molecules on the Si(100)-2 × 1 surface. Large molecule–substrate adsorption energies are computed and are found to compete with the molecule–molecule interactions of the double decker molecules. A particularly good matching between STM images and computed ones confirms the deformation of the molecule upon the absorption process. The comparison between DFT calculations and XP spectra reveals that the electronic distribution in the two plateaus …

Discovery of Retinoic Acid-Related Orphan Receptor γt Inverse Agonists via Docking and Negative Image-Based Screening

2018

Retinoic acid-related orphan receptor γt (RORγt) has a vital role in the differentiation of T-helper 17 (TH17) cells. Potent and specific RORγt inverse agonists are sought for treating TH17-related diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes. Here, the aim was to discover novel RORγt ligands using both standard molecular docking and negative image-based screening. Interestingly, both of these in silico techniques put forward mostly the same compounds for experimental testing. In total, 11 of the 34 molecules purchased for testing were verified as RORγt inverse agonists, thus making the effective hit rate 32%. The pIC50 values for the compounds varied from 4.9 (11 μ…

Diuron mobility through vineyard soils contaminated with copper

2005

International audience; The herbicide diuron is frequently applied to vineyard soils in Burgundy, along with repeated treatments with Bordeaux mixture (a blend of copper sulfate and calcium hydroxide) that result in elevated copper concentrations. Cu could in principle affect the fate and transport of diuron or its metabolites in the soil either directly by complexation or indirectly by altering the populations or activity of microbes involved in their degradation. To assess the effect of high Cu concentrations on diuron transport, an experiment was designed with ten undisturbed columns of calcareous and acidic soils contaminated with 17–509 mg kg−1 total Cu (field-applied). Grass was plant…