Search results for "41"

showing 10 items of 3365 documents

Microfluidic Synthesis of Actuating Microparticles from a Thiol-Ene Based Main-Chain Liquid Crystalline Elastomer.

2016

In this article the microfluidic synthesis of strongly actuating particles on the basis of a liquid crystalline main-chain elastomer is presented. The synthesis is carried out in a capillary-based co-flow microreactor by photo-initiated thiol-ene click chemistry of a liquid crystalline monomer mixture. These microparticles exhibit a deformation from a spherical to a rod-like shape during the thermal-initiated phase transition of the liquid crystalline elastomer (LCE) at which the particles’ aspect ratio is almost doubled. Repeated contraction cycles confirm the complete reversibility of the particles’ actuation properties. The transition temperature of the LCE, the temperature range of the …

Phase transitionMaterials sciencePolymers and PlasticsCapillary actionMicrofluidicsmicrofluidicsoft actuator02 engineering and technologycontinuous flow synthesis010402 general chemistryElastomer01 natural sciencesArticlestimuli-responsivelcsh:QD241-441Physics::Fluid Dynamicschemistry.chemical_compoundphoto polymerizationlcsh:Organic chemistryLiquid crystalliquid crystalComposite materialmicrofluidic; microparticles; liquid crystal; stimuli-responsive; soft actuator; thiol-ene; liquid crystalline elastomer; photo polymerization; continuous flow synthesismicroparticlesthiol-eneGeneral ChemistryAtmospheric temperature range021001 nanoscience & nanotechnology0104 chemical sciencesCondensed Matter::Soft Condensed MatterMonomerchemistryliquid crystalline elastomerMicroreactor0210 nano-technologyPolymers
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Semiflexible Polymers Interacting with Planar Surfaces: Weak versus Strong Adsorption

2020

Semiflexible polymers bound to planar substrates by a short-range surface potential are studied by Molecular Dynamics simulations to clarify the extent to which these chain molecules can be considered as strictly two-dimensional. Applying a coarse-grained bead-spring model, the chain length N and stiffness &kappa

Phase transitionPolymers and Plastics02 engineering and technology01 natural sciencesMolecular physicsGyrationArticlelcsh:QD241-441Molecular dynamicschain rigiditylcsh:Organic chemistry0103 physical sciencesPerpendicularMolecule010306 general physicspolymersPhysicschemistry.chemical_classificationPersistence lengthQuantitative Biology::Biomoleculesfood and beveragesGeneral ChemistryPolymer021001 nanoscience & nanotechnologymolecular dynamicsphase transitionsCondensed Matter::Soft Condensed MatterDistribution functionchemistryadsorption0210 nano-technologyPolymers
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„Die Gottesluft der freien Forschung“ – Jacobis Verhältnis zur französischen Mathematik aus politischer Sicht

2013

Published version of an article in the journal: Mitteilungen der Deutschen Mathematiker-Vereinigung (DMV)

PhilosophyGeneral EngineeringHumanitiesVDP::Mathematics and natural science: 400::Mathematics: 410VDP::Humanities: 000::Philosophical disciplines: 160::History of ideas: 162
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Für die Ehre des menschlichen Geistes - Ein neuer Blick auf eine bekannte Kontroverse zwischen Fourier und Jacobi über die Rolle der Anwendungen der …

2013

Published version of an article from the journal: Mitteilungen der Deutschen Mathematiker-Vereinigung (DMV)

PhilosophyGeneral EngineeringHumanitiesVDP::Mathematics and natural science: 400::Mathematics: 410VDP::Humanities: 000::Philosophical disciplines: 160::History of ideas: 162Mitteilungen der Deutschen Mathematiker-Vereinigung
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Dephosphorylation of Centrins by Protein Phosphatase 2C α and β.

2009

In the present study, we identified protein phosphatases dephosphorylating centrins previously phosphorylated by protein kinase CK2. The following phosphatases known to be present in the retina were tested: PP1, PP2A, PP2B, PP2C, PP5, and alkaline phosphatase. PP2C 𝛼 and 𝛽 were capable of dephosphorylating P-Thr138-centrin1 most efficiently. PP2C𝛿 was inactive and the other retinal phosphatases also had much less or no effect. Similar results were observed for centrins 2 and 4. Centrin3 was not a substrate for CK2. The results suggest PP2C 𝛼 and 𝛽 to play a significant role in regulating the phosphorylation status of centrins in vivo.

PhosphatasePyruvate dehydrogenase phosphataseBioinformaticsDephosphorylationlcsh:Chemistrylcsh:QD241-441lcsh:Biochemistrychemistry.chemical_compoundlcsh:Organic chemistryIn vivoResearch LetterMedicinelcsh:QD415-436lcsh:Sciencelcsh:QH301-705.5Earth-Surface Processesbusiness.industryRetinalProtein phosphatase 2Biochemistrychemistrylcsh:Biology (General)lcsh:QD1-999embryonic structuresAlkaline phosphatasePhosphorylationlcsh:QbusinessResearch letters in biochemistry
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n-3 PUFAs modulate T-cell activation via protein kinase C-α and -ε and the NF-κB signaling pathway

2005

We elucidated the mechanisms of action of two n-3 PUFAs, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), in Jurkat T-cells. Both DHA and EPA were principally incorporated into phospholipids in the following order: phosphatidylcholine < phosphatidylethanolamine < phosphatidylinositol/phosphatidylserine. Furthermore, two isoforms of phospholipase A(2) (i.e., calcium-dependent and calcium-independent) were implicated in the release of DHA and EPA, respectively, during activation of these cells. The two fatty acids inhibited the phorbol 12-myristate 13-acetate (PMA)-induced plasma membrane translocation of protein kinase C (PKC)-alpha and -epsilon. The two n-3 PUFAs also inhibited t…

PhosphatidylethanolaminePhospholipase Amitogen-activated protein kinaseProtein Kinase C-epsilonQD415-436Cell BiologyPhosphatidylserineBiologyfatty acidsBiochemistryJurkat cellsCell biologychemistry.chemical_compoundEndocrinologychemistryBiochemistryDocosahexaenoic acidlipids (amino acids peptides and proteins)Phosphatidylinositolnuclear factor κBProtein kinase Cpolyunsaturated fatty acidsJournal of Lipid Research
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Optimization of Innovative Three-Dimensionally-Structured Hybrid Vesicles to Improve the Cutaneous Delivery of Clotrimazole for the Treatment of Topi…

2019

New three-dimensionally-structured hybrid phospholipid vesicles, able to load clotrimazole in a high amount (10 mg/mL), were obtained for the first time in this work by significantly reducing the amount of water (&le

PhospholipidPharmaceutical Sciencelcsh:RS1-44102 engineering and technology030226 pharmacology & pharmacyArticleclotrimazolelcsh:Pharmacy and materia medica03 medical and health scienceschemistry.chemical_compound0302 clinical medicineIn vivophospholipid vesiclesX-raysCandida albicansElectron microscopymedicineGlycerolskin deliveryCandida albicansco-solventsPhospholipidsChromatographybiologyClotrimazoleSmall-angle X-ray scatteringVesicle021001 nanoscience & nanotechnologybiology.organism_classification<i>Candida albicans</i>Microscòpia electrònicachemistryTransmission electron microscopyfungal infectionsRaigs X0210 nano-technologyFosfolípidsmedicine.drugPharmaceutics
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Activity and Thermal Stability of Cobalt(II)-Based Olefin Polymerization Catalysts Adorned with Sterically Hindered Dibenzocycloheptyl Groups.

2019

Five examples of unsymmetrical 2-(2,4-bis(dibenzocycloheptyl)-6-methylphenyl- imino)ethyl)-6-(1-(arylyimino)ethyl)pyridine derivatives (aryl = 2,6-Me2C6H3 in L1

Photochemistry2Pharmaceutical Sciencechemistry.chemical_elementCatalysisArticlethermal stabilityAnalytical ChemistryPolymerizationlcsh:QD241-441chemistry.chemical_compoundDibenzocycloheptyl grouplcsh:Organic chemistryDrug DiscoveryPolymer chemistryPyridine26-bis(imino)pyridylcobalt(II) chloride precatalystsThermal stabilityPhysical and Theoretical ChemistryMolecular StructureOrganic ChemistryCobaltPolyethyleneSquare pyramidal molecular geometryLinear low-density polyethylene6-bis(imino)pyridylcobalt(II) chloride precatalystschemistryPolymerizationhigh molecular-weight saturated/unsaturated polyethyleneChemistry (miscellaneous)PolyethyleneMolecular MedicineMolar mass distributionCobaltMolecules (Basel, Switzerland)
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Carbon Nanodots: A Review—From the Current Understanding of the Fundamental Photophysics to the Full Control of the Optical Response

2018

Carbon dots (CDs) are an emerging family of nanosystems displaying a range of fascinating properties. Broadly speaking, they can be described as small, surface-functionalized carbonaceous nanoparticles characterized by an intense and tunable fluorescence, a marked sensitivity to the environment and a range of interesting photochemical properties. CDs are currently the subject of very intense research, motivated by their possible applications in many fields, including bioimaging, solar energy harvesting, nanosensing, light-emitting devices and photocatalyis. This review covers the latest advancements in the field of CDs, with a focus on the fundamental understanding of their key photophysica…

PhotoluminescenceMaterials science530 PhysicsultrafastphotophysicNanoparticleNanotechnology02 engineering and technology010402 general chemistry01 natural sciencesElectronic stateslcsh:QD241-441lcsh:Organic chemistryCarbon nanodotscarbon dots540 Chemistryfemtosecondcarbon dotphotophysicsphotochemistrynanocarbonSettore FIS/01 - Fisica SperimentaleGeneral Medicine021001 nanoscience & nanotechnology0104 chemical sciencesSolar energy harvestingFemtosecondfluorescence0210 nano-technologyUltrashort pulse
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Effect of Halogen Ions on the Photocycle of Fluorescent Carbon Nanodots

2019

Carbon dots (C-dots) are well-known for their strong sensitivity to the environment, which reflects on intensity and shape changes of their fluorescence, induced by various interacting ions and molecules in solution. Although these interactions have been extensively studied in the last few years, especially in view of their possible sensing applications, the existing works have mostly focused on the quenching of C-dot fluorescence induced by metal cations. In fact, these latter easily bind to C-dots surfaces, which are negatively charged in most cases, promoting an electron transfer from the surface to them. Much less is known from the literature on the effect induced on C-dots by prototypi…

Photoluminescencequenchingfluorescence quenching02 engineering and technology010402 general chemistryPhotochemistryultrafast transient absorption01 natural sciencesIonlcsh:QD241-441lcsh:Organic chemistrycarbon nanodotheavy atom effectPhysics::Atomic and Molecular ClustersMoleculecarbon nanodotsQuenching (fluorescence)ChemistrySettore FIS/01 - Fisica SperimentaleGeneral Medicine021001 nanoscience & nanotechnologyFluorescence0104 chemical sciencesIntersystem crossingHalogenAbsorption (chemistry)0210 nano-technologyC
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