Search results for "41"
showing 10 items of 3365 documents
Pētera Šmita sarakste ar latviešu un lietuviešu filologu, etnogrāfu Eduardu Volteri
1915
Vēstulē P. Šmits skaidro jēdzienu "krusta priedes", kā arī piemin E. Voltera pārizdoto veco Katehismu (Латышскій катехизисъ 1585 года / переизданный Э.А. Вольтеромъ. Петроградъ : тип. Акад. наук, 1915)ю
Pharmacokinetic/Pharmacodynamic Model of Neutropenia in Real-Life Palbociclib-Treated Patients
2021
Palbociclib is an oral CDK4/6 inhibitor indicated in HR+/HER2- advanced or metastatic breast cancer in combination with hormonotherapy. Its main toxicity is neutropenia. The aim of our study was to describe the kinetics of circulating neutrophils from real-life palbociclib-treated patients. A population pharmacokinetic (popPK) model was first constructed to describe palbociclib pharmacokinetic (PK). Individual PK parameters obtained were then used in the pharmacokinetic/pharmacodynamic (PK/PD) model to depict the relation between palbociclib concentrations and absolute neutrophil counts (ANC). The models were built with a population of 143 patients. Palbociclib samples were routinely collec…
Vor hundert Jahren: ein Gedenkblatt zur Säkularfeier des ältesten baltischen Romans: "Hippel's Lebensläufe"
1878
Losing weight after menopause with minimal aerobic training and mediterranean diet
2020
Objective: It is a common belief that menopausal women have greater difficulty losing weight. The aim of this study was to assess the efficacy of a Mediterranean diet (MD) to promote weight loss in postmenopausal women. All participants were prescribed a hypocaloric traditional MD, tailored to the individual. Subjects were asked not to begin any kind of physical activity. Body composition was measured at the beginning and after 8 weeks of treatment. In total, 89 women (age 52.8 ±
Multivariate Methods Based Soft Measurement for Wine Quality Evaluation
2014
Published version of an article in the journal: Abstract and Applied Analysis. Also available from the publisher at: http://dx.doi.org/10.1155/2014/740754 Open Access Soft measurement is a new, developing, and promising industry technology and has been widely used in the industry nowadays. This technology plays a significant role especially in the case where some key variables are difficult to be measured by traditional measurement methods. In this paper, the quality of the wine is evaluated given the wine physicochemical indexes according to multivariate methods based soft measurement. The multivariate methods used in this paper include ordinary least squares regression (OLSR), principal c…
Richard von Mises’ work for ZAMM until his emigration in 1933 and glimpses of the later history of ZAMM
2020
Investigating the Affordances and Constraints of SimReal for Mathematical Learning : A Case Study in Teacher Education
2019
Visualizations tools are one of the most innovative technologies that emerged the last few years in educational settings. They provide new potentialities for mathematical learning by means of dynamic animations and representations, interactive simulations, and live streaming of lessons. Moreover, visualization tools have the potential to foster a visual, dynamic, distributed, and embodied mathematics rather than individual achievements and static representations. This paper uses the visualization tool SimReal in teacher education to explore the affordances of the tool for learning mathematics. It proposes a framework that captures the affordances of SimReal at a technological, pedagogical, …
Iron’s Wake: The Performance of Quantum Mechanical-Derived Versus General-Purpose Force Fields Tested on a Luminescent Iron Complex
2020
Recently synthetized iron complexes have achieved long-lived excited states and stabilities which are comparable, or even superior, to their ruthenium analogues, thus representing an eco-friendly and cheaper alternative to those materials based on rare metals. Most of computational tools which could help unravel the origin of this large efficiency rely on ab-initio methods which are not able, however, to capture the nanosecond time scale underlying these photophysical processes and the influence of their realistic environment. Therefore, it exists an urgent need of developing new low-cost, but still accurate enough, computational methodologies capable to deal with the steady-state and trans…
Towards Stable Radial Basis Function Methods for Linear Advection Problems
2021
In this work, we investigate (energy) stability of global radial basis function (RBF) methods for linear advection problems. Classically, boundary conditions (BC) are enforced strongly in RBF methods. By now it is well-known that this can lead to stability problems, however. Here, we follow a different path and propose two novel RBF approaches which are based on a weak enforcement of BCs. By using the concept of flux reconstruction and simultaneous approximation terms (SATs), respectively, we are able to prove that both new RBF schemes are strongly (energy) stable. Numerical results in one and two spatial dimensions for both scalar equations and systems are presented, supporting our theoret…
Structure–Property Relationships in Bionanocomposites for Pipe Extrusion Applications
2021
In this work, bionanocomposites based on different biodegradable polymers and two types of nanofillers, namely a nanosized calcium carbonate and an organomodified nanoclay, were produced through melt extrusion, with the aim to evaluate the possible applications of these materials as a potential alternative to traditional fossil fuel-derived polyolefins, for the production of irrigation pipes. The rheological behavior of the formulated systems was thoroughly evaluated by exploiting different flow regimes, and the obtained results indicated a remarkable effect of the introduced nanofillers on the low-frequency rheological response, especially in nanoclay-based bionanocomposites. Conversely, t…