Search results for "41"

showing 10 items of 3365 documents

Physical activity at age of 20-64 years and mobility and muscle strength in old age: a community-based study.

2012

Background. Physical activity in midlife has been related to lower mortality and better health in old age. The present study evaluated whether physical activity at age of 20–64 years was associated with mobility and muscle strength in old age. Methods. A random sample of 1,000 persons was extracted from all the ≥75-year-old people living in Kuopio, Finland, and 679 community-dwelling participants were included in the present analyses. Data on health status, ability to walk outside or 400 m, and physical activity level were obtained through structured interviews. Participants’ walking speed, grip strength, and knee extension strength were measured by physiotherapists. Relationship between ph…

AdultMaleAgingmedicine.medical_specialtyKnee JointHealth StatusPhysical activityMotor ActivityLogistic regressionGrip strengthYoung AdultmedicineHumansMuscle StrengthMobility LimitationGeriatric AssessmentFinlandAgedHand Strengthbusiness.industryta3141Odds ratioMiddle AgedConfidence intervalPhysical activity levelPreferred walking speedMuscle strengthPhysical therapyFemaleGeriatrics and GerontologybusinessThe journals of gerontology. Series A, Biological sciences and medical sciences
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Free and antibody-complexed antigen and antibody profile in apparently healthy HIV seropositive individuals and in AIDS patients.

1990

The pattern of free and antibody-complexed HIV antigen and the antibody profile were investigated retrospectively in 305 serum samples taken from 22 AIDS patients before and during the development of AIDS and from 40 apparently healthy seropositive individuals. Most AIDS patients were found positive for both free and complexed antigen and had high gp41 antibody titres but low or undetectable p24 antibody. Four different patterns of HIV antigenaemia were observed: 1) positive for both free and complexed antigen; 2) negative for free HIV antigen at first, but always positive for complexed antigen; 3) positive for free antigen without complexed antigen; and 4) negative for both free and comple…

AdultMaleAntigen-Antibody ComplexHIV AntigensHIV Core Protein p24Gene Products gagAntigen-Antibody ComplexBiologyHIV AntibodiesVirusImmune systemAcquired immunodeficiency syndrome (AIDS)AntigenHIV SeroprevalenceVirologyHIV SeropositivitymedicineHumansSubstance Abuse IntravenousAcquired Immunodeficiency SyndromeViral Core Proteinsmedicine.diseaseVirologyImmune complexHIV Envelope Protein gp41Infectious DiseasesItalyImmunologybiology.proteinFemaleViral diseaseAntibodyBiomarkersJournal of medical virology
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Associations of LPL and APOC3 gene polymorphisms on plasma lipids in a mediterranean population: Interaction with tobacco smoking and the APOE locus

2002

We conducted a cross-sectional study in a Spanish population (n = 1,029) to investigate associations between the LPL and APOC3 gene loci (LPL-HindIII, LPL-S447X, and APOC3-SstI) and plasma lipid levels and their interaction with APOE polymorphisms and smoking. Carriers of the H− or the X447 allele had higher levels of HDL cholesterol (HDL-C), and lower levels of TG, after adjustment for age, body mass index, alcohol, smoking, exercise, and education (P < 0.01). The APOC3 polymorphism presented additive effects to the LPL variants on TG and HDL-C levels in men, and on TG in women. The most and the least favorable haplotype combinations were H−/X447/S1 and H+/S447/S2, respectively. These comb…

AdultMaleApolipoprotein Emedicine.medical_specialtyapolipoprotein C-IIIPopulationlipoprotein lipaseLocus (genetics)Deoxyribonuclease HindIIIQD415-436Biochemistrylipidschemistry.chemical_compoundApolipoproteins EEndocrinologyInternal medicineHumansMedicineAlleleApolipoproteins CDeoxyribonucleases Type II Site-SpecificeducationTriglyceridesGeneticseducation.field_of_studyLipoprotein lipasePolymorphism Geneticbusiness.industryCholesterolCholesterol HDLSmokingHaplotypeGenetic Variationnutritional and metabolic diseasesCell BiologyCross-Sectional StudiesEndocrinologychemistrySpainFemalelipids (amino acids peptides and proteins)gene-environmental interactionbusinessBody mass index
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Perceived Racial/Ethnic Discrimination and Psychological Outcomes Among Adult International Adoptees in Finland: Moderating Effects of Social Support…

2015

Quantitative literature on international adoptees and racial/ethnic discrimination is lacking despite results in qualitative studies from Europe and the United States that have consistently indicated how racism constantly complicates adoptees' everyday lives. To advance the literature, the present study examined the prevalence of perceived racial/ethnic discrimination among 213 adult international adoptees in Finland (59.6% women and 40.4% men, mean age 24.1 years), and the association between perceived racial/ethnic discrimination and psychological well-being indicators, including psychological distress and sleeping problems. In addition, we examined social support and sense of coherence a…

AdultMaleAsiaSense of Coherencemedia_common.quotation_subjectinternational adoptionPsycINFOsense of coherenceRacismDevelopmental psychologySocial supportYoung AdultRacismArts and Humanities (miscellaneous)psychological distresssleeping problemsAdoptionDevelopmental and Educational PsychologyHumansta516Europe EasternYoung adultAssociation (psychology)ta515Finlandmedia_commonSocial Supportracial/ethnic discriminationSouth AmericaMental healthta3123Psychiatry and Mental healthDistressta5141AfricaFemalePsychology (miscellaneous)PsychologyStress PsychologicalQualitative researchAmerican Journal of Orthopsychiatry
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Lay understanding of the causes of binge drinking in the United Kingdom and Australia: a network diagram approach

2017

​Binge drinking is associated with deleterious health, social and economic outcomes. This study explored the lay understanding of the causes of binge drinking in members of the general public in the United Kingdom and Australia. Participants in the United Kingdom (N = 133) and Australia (N = 102) completed a network diagram exercise requiring them to draw causal paths and provide path strength ratings between 12 candidate factors (24-h opening, age, alcohol advertizing, alcohol availability, boredom, drinking culture, income, low cost, parental influence, peer pressure, stress and supermarket discounts) and binge drinking. Results indicated good consistency in paths across samples, although…

AdultMaleC850 Cognitive Psychologymedicine.medical_specialtyC840 Clinical Psychologypeer pressure030508 substance abuseBinge drinkingPublic opinionboredomPeer GroupEducationParental influence03 medical and health sciencesC841 Health PsychologyC810 Applied Psychology0302 clinical medicinemedicineHumans030212 general & internal medicinePeer pressurePsychiatryPath analysis (statistics)Causal modelModels Statisticalbusiness.industryAustraliaPublic Health Environmental and Occupational HealthSocial Supportta3141BoredomDrinking cultureAwarenessC800 PsychologyUnited Kingdombinge drinkingFemaleethanolmedicine.symptom0305 other medical sciencebusinessPsychologyHealth Education Research
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Orderly display of limb lead ECGs raises Chinese intern’s diagnostic accuracy when determining frontal plane QRS axis

2019

Background: There is limited information on whether the orderly display of limb lead ECGs (electrocardiograms) can facilitate students to determine frontal plane QRS complex wave electrical axis. Objectives: The study investigated whether the orderly display of limb lead ECGs can raise Chinese undergraduate intern’s diagnostic accuracy when determining frontal plane axis. Design: A total of 147 fifth-year undergraduate interns aged between 21 and 25 years were randomly arranged into 2 groups: one group was given classically displayed ECGs of limb leads while the other group was given orderly displayed ECGs of limb leads. They were then taught to determine frontal plane axis with one of the …

AdultMaleChinamedicine.medical_specialtyShort CommunicationelectrocardiographykardiologiaDiagnostic accuracymedical teachingelectrocardiogrammedical learningEducationYoung AdultQRS complexInternal medicinemedicineHumanscardiovascular diseasesLead (electronics)ta315EKGMedical educationlcsh:LC8-6691lcsh:R5-920medicine.diagnostic_testlcsh:Special aspects of educationbusiness.industryClinical Clerkshipfood and beveragesta3141General Medicineta3121diagnostiikkaMedical teachingkoulutusCoronal planecardiovascular systemCardiologyFemaleQrs axisbusinesslcsh:Medicine (General)medical educationElectrocardiographycirculatory and respiratory physiologyMedical Education Online
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Physical activity in adulthood: genes and mortality.

2015

AbstractObservational studies report a strong inverse relationship between leisure-time physical activity and all-cause mortality. Despite suggestive evidence from population-based associations, scientists have not been able to show a beneficial effect of physical activity on the risk of death in controlled intervention studies among individuals who have been healthy at baseline. On the other hand, high cardiorespiratory fitness is known to be a strong predictor of reduced mortality, even more robust than physical activity level itself. Here, in both animals and/or human twins, we show that the same genetic factors influence physical activity levels, cardiorespiratory fitness and risk of de…

AdultMaleFOOD-INTAKEPopulationPhysiologyMonozygotic twinphysical activityVOLUNTARY EXERCISEKaplan-Meier EstimateMotor ActivityBioinformaticsArticleYoung AdultGenetic PleiotropyadultsTwins DizygoticMedicineAnimalsHumansINTRINSIC AEROBIC CAPACITYYoung adultMortalityeducationta315genesFINNISH TWIN COHORTaikuisetGenetic Association StudiesALL-CAUSE MORTALITYeducation.field_of_studyMultidisciplinarygeenitbusiness.industryCardiorespiratory fitnessta3141LEISURE-TIMETwins MonozygoticTwin studymortalityPhysical activity level3142 Public health care science environmental and occupational healthRatsBODY-WEIGHTCHRONIC DISEASEObservational studyFemalebusinessCARDIORESPIRATORY FITNESSFollow-Up StudiesScientific reports
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Health literacy in familial hypercholesterolemia: A cross-national study.

2018

Background High rates of inadequate health literacy are associated with maladaptive health outcomes in chronic disease including increased mortality and morbidity rates, poor treatment adherence and poor health. Adequate health literacy may be an important factor in the effective treatment and management of familial hypercholesterolemia, and may also be implicated in genetic screening for familial hypercholesterolemia among index cases. The present study examined the prevalence and predictors of health literacy in familial hypercholesterolemia patients attending clinics in seven countries. Design Cross-sectional survey. Methods Consecutive FH patients attending clinics in Australia, Brazil,…

AdultMaleHealth Knowledge Attitudes PracticeAsiaEpidemiologyHealth literacyFamilial hypercholesterolemia030204 cardiovascular system & hematologyHyperlipoproteinemia Type II03 medical and health sciences0302 clinical medicineAsian PeopleEnvironmental healthSurveys and QuestionnairesInternal MedicineMedicineEffective treatmentHumans030212 general & internal medicineta315health disparitiesAgedfamilial hypercholesterolemiabusiness.industrydyslipidemiaAge FactorsAustraliata3141General Medicinegenetic screeningMiddle Agedmedicine.diseaseHealth equityUnited KingdomHealth LiteracyChronic diseaseCross-Sectional StudiesIncomeHousehold incomeFemaleMETABOLISMObusinessCardiology and Cardiovascular Medicinehealth literacyDyslipidemiaCross nationalEuropean journal of preventive cardiology
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Improved Nutritional Knowledge in the Obese Adult Population Modifies Eating Habits and Serum and Anthropometric Markers

2020

Multicomponent lifestyle interventions achieve good results in the management of obesity among the adult population. However, their implementation in certain populations poses difficulties. A good level of nutritional knowledge enables people to make changes in their diet that improve their health. This study aims to assess the relationship between nutritional knowledge and nutritional parameters such as dietary intake, anthropometric parameters and biomarkers. A before&ndash

AdultMaleHealth Knowledge Attitudes PracticeobesitymacronutrientsPopulation030209 endocrinology & metabolismlcsh:TX341-641OverweightArticleManagement of obesity03 medical and health sciences0302 clinical medicineWeight lossEnvironmental healthIntervention (counseling)energy expendituremedicineHumansNutritional Physiological Phenomena030212 general & internal medicineeducationeducation.field_of_studyNutrition and DieteticsattitudesAnthropometrybusiness.industryFeeding BehaviorMiddle AgedAnthropometryMicronutrientmedicine.diseaseObesityhealth knowledgeFoodmicronutrientsLinear ModelsFemalemedicine.symptombusinessdietlcsh:Nutrition. Foods and food supplyBiomarkersFood ScienceNutrients
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Tidal Volume Estimation during Helmet Noninvasive Ventilation: an Experimental Feasibility Study

2019

AbstractWe performed a bench (BS) and human (HS) study to test the hypothesis that estimation of tidal volume (VT) during noninvasive helmet pressure support ventilation (nHPSV) would be possible using a turbine driven ventilator (TDV) coupled with an intentional leak single-limb vented circuit. During the BS a mannequin was connected to a lung simulator (LS) and at different conditions of respiratory mechanics, positive end expiratory pressure (PEEP) levels and leaks (30, 50 and 80 L/min). All differences were within the 95% limits of agreement (LoA) in all conditions in the Bland-Altman plot. The overall bias (difference between VT measured by TDV and LS) was 35 ml (95% LoA 10 to 57 ml), …

AdultMaleLeakmedicine.medical_specialtylcsh:MedicineSettore MED/41 - AnestesiologiaPressure support ventilationTherapeuticsRespiratory physiologyManikinsArticlePositive-Pressure Respiration03 medical and health sciences0302 clinical medicineInternal medicineHealthy volunteersTidal VolumemedicineHumanslcsh:SciencePositive end-expiratory pressureTidal volumeMouthpieceVentilators Mechanicalacute respiratory failureMultidisciplinarybusiness.industrylcsh:RhelmetReproducibility of Resultsnoninvasive ventilation030208 emergency & critical care medicineEquipment DesignHealthy Volunteers030228 respiratory systemPreclinical researchRespiratory MechanicsCardiologyFeasibility Studieslcsh:QFemaleHead Protective DevicesNoninvasive ventilationbusinessScientific Reports
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