Search results for "42"

showing 10 items of 3911 documents

Chicken adaptive response to low energy diet: main role of the hypothalamic lipid metabolism revealed by a phenotypic and multi-tissue transcriptomic…

2019

AbstractBackgroundProduction conditions of layer chicken can vary in terms of temperature or diet energy content compared to the controlled environment where pure-bred selection is undertaken. The aim of this study was to better understand the long-term effects of a 15%-energy depleted diet on egg-production, energy homeostasis and metabolism via a multi-tissue transcriptomic analysis. Study was designed to compare effects of the nutritional intervention in two layer chicken lines divergently selected for residual feed intake.ResultsChicken adapted to the diet in terms of production by significantly increasing their feed intake and decreasing their body weight and body fat composition, whil…

Adipose tissueadaptationEnergy homeostasisTranscriptome0302 clinical medicinehypothalamusBeta oxidation2. Zero hunger0303 health sciencesprise alimentaireEndocannabinoid systemAdaptation PhysiologicalCell biologyAlimentation et NutritionBody Composition[SDV.NEU]Life Sciences [q-bio]/Neurons and Cognition [q-bio.NC]BiotechnologyResearch Articlelcsh:QH426-470FADS1FADS2lcsh:BiotechnologychickenpouletBiologyModels Biological03 medical and health sciencesQuantitative Trait Heritablelipidlcsh:TP248.13-248.65GeneticsAnimalsFood and Nutritionlipide030304 developmental biologyCaloric RestrictionNeurosciencesLipid metabolismLipid MetabolismDietlcsh:GeneticsGene Expression RegulationNeurons and Cognitionfeed intakeEnergy MetabolismChickenstranscriptome;lipid;feed intake;adaptation;hypothalamus;chickentranscriptome[SDV.AEN]Life Sciences [q-bio]/Food and Nutrition030217 neurology & neurosurgery
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The economic impact of rectal cancer: A population-based study in Italy list of authors

2021

Costs of cancer care are increasing worldwide, and sustainability of cancer burden is critical. In this study, the economic impact of rectal cancer on the Italian healthcare system, measured as public healthcare expenditure related to investigation and treatment of rectal cancer patients is estimated. A cross-sectional cohort of 9358 rectal cancer patients is linked, on an individual basis, to claims associated to rectal cancer diagnosis and treatments. Costs refer mainly to years 2010&ndash

Administrative databasesAdministrative databases Cancer registry Cost analysis Patterns of care Prevalence Real-world data Cross-Sectional Studies Delivery of Health Care Health Care Costs Humans Italy Health Expenditures Rectal Neoplasmslcsh:RPatterns of careCost analysisPrevalencelcsh:MedicineCancer registrySettore MED/42 - Igiene Generale E ApplicataReal-world data
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Worldwide trends in population-based survival for children, adolescents, and young adults diagnosed with leukaemia, by subtype, during 2000–14 (CONCO…

2022

BACKGROUND Leukaemias comprise a heterogenous group of haematological malignancies. In CONCORD-3, we analysed data for children (aged 0-14 years) and adults (aged 15-99 years) diagnosed with a haematological malignancy during 2000-14 in 61 countries. Here, we aimed to examine worldwide trends in survival from leukaemia, by age and morphology, in young patients (aged 0-24 years). METHODS We analysed data from 258 population-based cancer registries in 61 countries participating in CONCORD-3 that submitted data on patients diagnosed with leukaemia. We grouped patients by age as children (0-14 years), adolescents (15-19 years), and young adults (20-24 years). We categorised leukaemia subtypes a…

AdolescentAustralia610 Medicine & healthlymphomaSettore MED/42 - Igiene Generale E ApplicatasurvivalUnited StatesEuropeLeukemia Myeloid AcuteYoung Adultchildrenpopulation-based/cancer registry360 Social problems & social servicessurvival leukemia cancer registryHematologic NeoplasmsleukaemiaPediatrics Perinatology and Child HealthDevelopmental and Educational PsychologycancerHumansRegistrieshaematological malignancy610 Medicine & healthChild360 Social problems & social services
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[The distribution of hepatitis C virus (HCV) genotypes in the drug-dependent population in Palermo].

1999

AdultAdolescentGenotypeUrban PopulationSubstance-Related Disordershepatitis C antibodyHepacivirusHepatitis C AntibodiesSettore MED/42 - Igiene Generale E Applicatavirus RNAHumansRNA ViralSicilyRetrospective StudiesAnnali di igiene : medicina preventiva e di comunita
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[Herpes Zoster and its prevention in Italy. Scientific consensus statement].

2014

In this paper, an Italian group of experts presents a revision of the available data about epidemiology and prevention of Herpes Zoster (HZ). HZ is an acute viral diseases caused by the reactivation of Varicella Zoster Virus (VZV). HZ is characterized by neurological and dermatological symptoms with a dermatomeric localization. The reactivation of the virus from the latent status in the sensitive ganglia increases with age and failing cell mediated immunity. In Europe, more than 95% of adults presents antibodies against VZV. Incidence of HZ is similar all over the world, related to the age of the population: from 2-3/1000 persons/year in the age group 20 to 50 years to 5/1000 in the 60 year…

AdultAged 80 and overClinical Trials as TopicEvidence-Based MedicineSettore MED/17 - Malattie InfettiveIncidenceSocio-culturaleNeuralgia Postherpeticconsensus statementMiddle AgedSettore MED/42 - Igiene Generale E ApplicataHerpes ZosterAge DistributionItalyRisk Factors80 and overNeuralgiaHerpes Zoster VaccineHumansAdult; Age Distribution; Aged; Aged 80 and over; Clinical Trials as Topic; Evidence-Based Medicine; Herpes Zoster; Herpes Zoster Vaccine; Humans; Incidence; Italy; Middle Aged; Neuralgia Postherpetic; Risk Factors; SicilyPostherpeticSicilyprevention of herpes zosterAgedIgiene e sanita pubblica
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Maternal Parenting Styles and Glycemic Control in Children with Type 1 Diabetes

2019

The purpose of this study is to examine differences in parenting styles between mothers of children with type 1 diabetes and mothers of healthy children and to explore relationships between parenting styles and glycemic control of children with diabetes. Mothers of 63 children with diabetes and mothers of 83 children without diabetes reported their parenting styles using the Blocks&rsquo

AdultBlood GlucoseMaleglykeeminen indeksitype 1 diabetesHealth Toxicology and MutagenesisControl (management)Mothers030209 endocrinology & metabolismArticle03 medical and health sciencesChild Rearing0302 clinical medicinechildrenPsychological controlDiabetes mellitusParenting stylesmedicineHumans030212 general & internal medicineChildta515GlycemicType 1 diabetesdiabetesParentingChild rearingbusiness.industrynuoruustyypin diabetesPublic Health Environmental and Occupational Healthta3142medicine.diseaseäiditparenting stylevanhemmatDiabetes Mellitus Type 1kontrolliglycemic controlFemalebusinessClinical psychologyInternational Journal of Environmental Research and Public Health
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Immune profiling of Alzheimer patients

2011

Abstract Alzheimer's disease (AD) is characterized by extracellular senile plaques in the brain, containing amyloid-β peptide (Aβ). We identify immunological differences between AD patients and age-matched controls greater than those related to age itself. The biggest differences were in the CD4 + rather than the CD8 + T cell compartment resulting in lower proportions of naive cells, more late-differentiated cells and higher percentages of activated CD4 + CD25 + T cells without a Treg phenotype in AD patients. Changes to CD4 + cells might be the result of chronic stimulation by Aβ present in the blood. These findings have implications for diagnosis and understanding the aetiology of the dis…

AdultCD4-Positive T-LymphocytesMaleImmunosenescenceT cellImmunologyStimulationDiseaseCD8-Positive T-LymphocytesBiologyYoung AdultAlzheimer DiseaseExtracellularmedicineHumansImmunology and AllergySenile plaquesAgedAged 80 and overSettore MED/04 - Patologia GeneraleGene Expression ProfilingAβ42Age FactorsT cellCell DifferentiationImmunosenescenceMiddle AgedAlzheimer's diseasePhenotypeCD4 Lymphocyte Countmedicine.anatomical_structureNeurologyImmunologyEtiologyFemaleNeurology (clinical)BiomarkersJournal of Neuroimmunology
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Capacity assessment for provision of quality sexual reproductive health and HIV-integrated services in Karamoja, Uganda

2020

Introduction: Sexual and reproductive health (SRH) and Human Immunodeficiency Virus (HIV) are crucial global health issues. Uganda continues to sustain a huge burden of HIV and AIDS.
 Methods: A cross-sectional health facility-based assessment was performed in November and December 2016 in Karamoja Region, northern Uganda. All the 126 health facilities (HFs) in Karamoja, including 5 hospitals and 121 Health Centers (HCs), covering 51 sub-counties of the 7 districts were assessed. We assessed the capacity of a) leadership and governance, b) human resource, c) service delivery, d) SRH and HIV service integration and e) users satisfaction and perceptions.
 Results: 64% of the establi…

AdultCapacity BuildingAdolescentService delivery framework030231 tropical medicineStaffingHIV InfectionsSettore MED/42 - Igiene Generale E ApplicataYoung Adult03 medical and health sciences0302 clinical medicineAcquired immunodeficiency syndrome (AIDS)Health facilitySurveys and QuestionnairesEnvironmental healthGlobal healthHumansMedicineUgandaHIV-Integrated ServicesHuman resourcesReproductive healthService (business)Delivery of Health Care Integratedbusiness.industryArticlesGeneral MedicineMiddle Agedmedicine.diseaseQuality Sexual Reproductive HealthQuality Sexual Reproductive Health HIV-Integrated Services Karamoja UgandaCross-Sectional StudiesReproductive HealthSocioeconomic FactorsFemaleReproductive Health ServicesHealth FacilitiesSexual HealthbusinessKaramoja
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Reliability and validity of the Finnish version of the Lower Extremity Functional Scale (LEFS)

2017

The present study aimed to assess the psychometric properties of the Finnish version of the Lower Extremity Functional Scale (LEFS) among foot and ankle patients.The LEFS was translated and cross-culturally adapted to Finnish. We assessed the test-retest reliability, internal consistency, floor-ceiling effect, construct validity and criterion validity in patients who underwent surgery due to musculoskeletal pathology of the foot and ankle (N = 166).The test-retest reliability was high (ICC = 0.93, 95% CI: 0.91-0.95). The standard error of measurement was 4.1 points. The Finnish LEFS showed high internal consistency (Cronbach's α = 0.96). A slight ceiling effect occurred as 17% achieved the …

AdultCross-Cultural ComparisonMalemedicine.medical_specialtyvalidityPsychometricsPsychometrics03 medical and health sciencesDisability Evaluation0302 clinical medicinePhysical medicine and rehabilitationCronbach's alphaSurveys and QuestionnairesCriterion validityMedicineHumansDisabled Persons030212 general & internal medicineAnkle painReliability (statistics)FinlandAgedLanguageta3126reliabilitybusiness.industryLower Extremity Functional ScaleRehabilitationFinnishConstruct validityReproducibility of Resultsta3141Middle Aged3126 Surgery anesthesiology intensive care radiology3142 Public health care science environmental and occupational healthmedicine.anatomical_structureLower ExtremityPhysical therapyCeiling effectFemaleLEFSAnklebusiness030217 neurology & neurosurgeryAnkle Joint
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Learning to Cycle : A Cross-Cultural and Cross-Generational Comparison

2022

BackgroundLearning to cycle is an important milestone for children, but the popularity of cycling and the environmental factors that promote the development and practice of this foundational movement skill vary among cultures and across time. This present study aimed to investigate if country of residence and the generation in which a person was born influence the age at which people learn to cycle.MethodsData were collected through an online survey between November 2019 and December 2020. For this study, a total of 9,589 responses were obtained for adults (self-report) and children (parental report) living in 10 countries (Portugal, Italy, Brazil, Finland, Spain, Belgium, United Kingdom, M…

AdultCross-Cultural ComparisonParentscyclingoppiminenympäristötekijätcountryLCSocial Scienceslapset (ikäryhmät)sukupolvetasenteetliikuntakulttuurichildrenRA0421kulttuuriSurveys and QuestionnairesgenerationMedicine and Health SciencesHumansChildpyöräilymatkustaminenPublic Health Environmental and Occupational Healthactive travelSpainliikkuminencycling country generation active travel childrenBrazilfyysinen aktiivisuus
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