Search results for "43"
showing 10 items of 1438 documents
Anodal tDCS over the left prefrontal cortex does not cause clinically significant changes in circulating metabolites
2020
Background: Transcranial direct current stimulation (tDCS), a putative treatment for depression, has been proposed to affect peripheral metabolism. Metabolic products from brain tissue may also cross the blood–brain barrier, reflecting the conditions in the brain. However, there are no previous data regarding the effect of tDCS on circulating metabolites.\ud Objective: To determine whether five daily sessions of tDCS modulate peripheral metabolites in healthy adult men.\ud Methods: This double-blind, randomized controlled trial involved 79 healthy males (aged 20–40 years) divided into two groups, one receiving tDCS (2 mA) and the other sham stimulated. The anode was placed over the left dor…
Shining castles and humans of metal/floral appearance ? metaphorical language in the Palaiologan romances Kallimachos and Velthandros
2019
About eight centuries after Heliodorus, the Greek novel resurfaced in the twelfth century, in Komnenian Byzantium, and again two centuries later under the Palaiologan dynasty. This latter literary revival was due to the political stability of the imperial Byzantine government, which promoted cultural production, rhetorical education, and patronage networks. Kallimachos and Velthandros, two Palaiologan romances presented as court literature, combine ancient and medieval tropes with rhetorical artistry to blur the boundaries between the artificial and the natural. Castles and objects made of precious metals thus resemble living, natural spaces, and human characters are portrayed in metallurgi…
From High-Throughput Microarray-Based Screening to Clinical Application: The Development of a Second Generation Multigene Test for Breast Cancer Prog…
2013
Several multigene tests have been developed for breast cancer patients to predict the individual risk of recurrence. Most of the first generation tests rely on proliferation-associated genes and are commonly carried out in central reference laboratories. Here, we describe the development of a second generation multigene assay, the EndoPredict test, a prognostic multigene expression test for estrogen receptor (ER) positive, human epidermal growth factor receptor (HER2) negative (ER+/HER2−) breast cancer patients. The EndoPredict gene signature was initially established in a large high-throughput microarray-based screening study. The key steps for biomarker identification are discussed in det…
Minori autori di reati sessuali: un’analisi prelimiare sui casi giudicati dal tribunale per i minorenni di Palermo negli anni 2005-2009
2012
L’allarme sociale in ordine agli abusi sessuali sui minori è accresciuto negli anni unitamente alla consapevolezza dell’importanza della tutela del minore e del valore fondamentale delle sue relazioni nel corso dello sviluppo. Il presente studio intende essere un contributo di conoscenza su una specifica categoria di abusanti: i minorenni. Uno studio delle peculiarità di tale fenomeno è premessa indispensabile per predisporre idonee ed efficaci strategie di trattamento. Al fine di identificare il numero e le caratteristiche dei minori abusanti si è proceduto a consultare i fascicoli del Tribunale per i Minorenni di Palermo relativi ad un periodo compreso fra il 2005 e il 2009. Tale indagine…
Molecular cloning, gene structure and expression profile of two mouse peroxisomal 3-ketoacyl-CoA thiolase genes
2004
Abstract Background In rats, two peroxisomal 3-ketoacyl-CoA thiolase genes (A and B) have been cloned, whereas only one thiolase gene is found in humans. The aim of this study was thus to clone the different mouse thiolase genes in order to study both their tissue expression and their associated enzymatic activity. Results In this study, we cloned and characterized two mouse peroxisomal 3-ketoacyl-CoA thiolase genes (termed thiolase A and B). Both thiolase A and B genes contain 12 exons and 11 introns. Using RNA extracted from mouse liver, we cloned the two corresponding cDNAs. Thiolase A and B cDNAs possess an open reading frame of 1272 nucleotides encoding a protein of 424 amino acids. In…
Morte improvvisa coronarica in soggetto con TBC polmonare miliarica e miocardite granulomatosa specifica. Correlazioni istopatogenetiche
2013
Myocardial bridge pathology and preventable accidents during physical activity of healthy subjects: A case report and a literature review.
2020
Myocardial bridging is a congenital coronary pathology described as a segment of coronary artery which courses through the myocardial wall under the muscle bridge. Although the prognosis of myocardial bridging is benign, sports medicine recognises myocardial bridging as a leading cause of sudden death among young basketball, football and soccer players. The authors report a case of a 42-year-old man who collapsed while playing football. He died notwithstanding prompt medical assistance and cardiopulmonary resuscitation. At autopsy, gross examination of the heart revealed the intramural course of the left anterior descending coronary artery to be 2 cm from its coronary ostial origin. Histol…
CCDC 938974: Experimental Crystal Structure Determination
2014
Related Article: Lena Kaufmann, Nora L. Traulsen, Andreas Springer, Hendrik V. Schröder, Toni Mäkelä, Kari Rissanen, Christoph A. Schalley|2014|Org.Chem.Front.|1|521|doi:10.1039/C4QO00077C
CCDC 1577820: Experimental Crystal Structure Determination
2018
Related Article: Zoran Džolić, Ngong Kodiah Beyeh, Mario Cetina, Lotta Turunen, Kari Rissanen|2018|Chem.Asian J.|13|164|doi:10.1002/asia.201701426
Desigualdad social y toma de decisiones en los comunales: El gobierno del mayor canal de riego de España (la Acequia Real del Júcar, Valencia) en el …
2021
espanolHacia 1850 la Acequia Real del Jucar era el mayor sistema comunitario de riego de Espana y se caracterizaba por la fuerte desigualdad social entre los regantes. El articulo analiza los cambios que experimentaron las instituciones para su gobierno en una etapa de profundas transformaciones sociales y politicas en la sociedad espanola, la segunda mitad del siglo XIX. Los organos de gobierno del canal estaban sujetos a una organizacion de tipo jerarquico que comprendia dos grandes niveles: por una parte, estaba la direccion del conjunto del sistema, en la que solo una reducida elite de terratenientes podia intervenir; por otra, habia organos de gestion local que administraban las sucesi…