Search results for "43"

Self-phase modulation-based 2R regenerator including pulse compression and offset filtering for 42.6 Gbit/s RZ-33% transmission systems

2009

International audience; We report on the experimental and theoretical study of a self-phase-modulation-based regenerator at 42.6 Gbit/s with a return-to-zero 33% format. We point out some detrimental effects such as intrachannel interactions and Brillouin scattering. An efficient solution, relying on a self-phase-modulation-based pulse compressor in combination with the regenerator, is proposed to overcome these detrimental phenomena. The experimental demonstration shows the effectiveness of a wavelength-transparent regenerator at 42.6 Gbit/s with a sensitivity-improvement of more than 5 dB and an eye-opening improvement of 2.3 dB in a back-to-back configuration, as well as a 10 times maxim…

Effects of atypical antipsychotics on neurocognition in euthymic bipolar patients.

2011

Abstract Background Different factors may influence cognitive functioning in bipolar disorder such as the effect of subsyndromal symptoms, the history of psychotic symptomatology or substance abuse, negative symptomatology, chronicity, sleep disturbances, and hormonal factors. The effect of pharmacologic treatment on cognition is still uncertain because of an insufficient number of studies examining this issue. Objective The aims of this study were to compare neuropsychologic performance of treated bipolar patients with that of controls, including unmedicated patients and healthy subjects, as well as to evaluate possible neurocognitive differences among 3 different atypical antipsychotics. …

Synaptogenesis in the mouse olfactory bulb during glomerulus development

2008

Synaptogenesis is essential for the development of neuronal networks in the brain. In the olfactory bulb (OB) glomeruli, numerous synapses must form between sensory olfactory neurons and the dendrites of mitral/tufted and periglomerular cells. Glomeruli develop from E13 to E16 in the mouse, coincident with an increment of the neuropil in the border between the external plexiform (EPL) and olfactory nerve layers (ONL), coupled to an extensive labelling of phalloidin and GAP-43 from the ONL to EPL. We have tracked synaptogenesis in the OB during this period by electron microscopy (EM) and immunolabelling of the transmembrane synaptic vesicle glycoprotein SV-2. No SV-2 labelling or synapses we…

Los cuidados a domicilio y las plataformas digitales en España

2021

Functional Connectivity of Nucleus Accumbens and Medial Prefrontal Cortex With Other Brain Regions During Early-Abstinence Is Associated With Alcohol…

2021

Background: Alcohol dependence (AD) is a chronic recurrent brain disease that causes a heavy disease burden worldwide, partly due to high relapse rates after detoxification. Verified biomarkers are not available for AD and its relapse, although the nucleus accumbens (NAc) and medial prefrontal cortex (mPFC) may play important roles in the mechanism of addiction. This study investigated AD- and relapse-associated functional connectivity (FC) of the NAc and mPFC with other brain regions during early abstinence.Methods: Sixty-eight hospitalized early-abstinence AD male patients and 68 age- and education-matched healthy controls (HCs) underwent resting-functional magnetic resonance imaging (r-f…

The BaBar detector: Upgrades, operation and performance

2013

The BABAR detector operated successfully at the PEP-Il asymmetric e(+) e(-) collider at the SLAC National Accelerator Laboratory from 1999 to 2008. This report covers upgrades, operation, and performance of the collider and the detector systems, as well as the trigger, online and offline computing, and aspects of event reconstruction since the beginning of data taking.

A return to humane medicine: Osler's legacy.

2017

Sir William Osler is celebrated today not only for his contributions to the advancement of medical education, but also for the humanism he brought to the practice of medicine. He was a doctor whose bedside skills and manners were emulated, and can legitimately be called an infectious diseases specialist. Nonetheless, he was also a humanist in the broader sense of the term, a student of human affairs and human nature, who emphasised compassion for the individual. To what extent, if any, are today's challenges influenced by departures from the paradigms created by Osler? In this paper we sought to ascertain whether such a tradition is still relevant to current practice and may foster a new pe…

Emergence of extreme events in fiber-based parametric processes driven by a partially incoherent pump wave

2009

Modulation instability (MI) generated by a picosecond coherent pulse has been recently identified as the key element of the generation of optical rogue-waves in supercontinuum-based systems [1]. Similar rare but highly energetic pulse structures can also appear in non-solitonic configurations such as Raman amplifiers driven by a partially incoherent pump wave propagating in fibres with low group velocity dispersion [2]. Therefore, one may wonder whether optical rogue-like event can also occur in MI-based amplifier because both Raman and parametric amplifiers benefit from a quasi-instantaneous gain. We provide here experimental evidence of rare optical events in a parametric amplifier in pre…

Generation of localized pulses from incoherent wave in optical fiber lines made of concatenated Mamyshev regenerators

2008

International audience; We investigate the novel properties of optical fiber lines made of Mamyshev regenerators (MRs) based on self-phase modulation and subsequent spectral filtering. In particular, we show that such a regenerator line can be used to generate random sequences of optical pulses from an incoherent wave. This behavior is related to the existence of stable eigenpulses that can propagate unchanged through the regenerator line and act as attractors for incoming pulses. By changing the regenerator parameters, we also report the existence of multiple eigenpulses and limit cycles. Finally, we demonstrate that MRs could be used as efficient nonlinear gates in fiber laser cavities.

Banki-Michell Optimal Design by Computational Fluid Dynamics Testing and Hydrodynamic Analysis

2013

In hydropower, the exploitation of small power sources requires the use of small turbines that combine efficiency and economy. Banki-Michell turbines represent a possible choice for their simplicity and for their good efficiency under variable load conditions. Several experimental and numerical tests have already been designed for examining the best geometry and optimal design of cross-flow type machines, but a theoretical framework for a sequential design of the turbine parameters, taking full advantage of recently expanded computational capabilities, is still missing. To this aim, after a review of the available criteria for Banki-Michell parameter design, a novel two-step procedure is de…