Search results for "44"

Cytokine Polymorphism in Takotsubo Cardiomyopathy

2014

IMIN11. Cytokine Polymorphism in Takotsubo Cardiomyopathy P. Di Gangi1, L. Scola1, S. Giambanco1, M. Bova1, G. Santini1, L. Vaccarino1, C. R. Balistreri1, D. Lio1, P. Assennato1, S. Novo1, G. Novo1 1University of Palermo, Palermo, Italy Background: Takotsubo (TT) cardiomyopathy is characterised by an acute left ventricular dysfunction triggered by emotional or physical stresses. Clinically, the syndrome is characterised by acute symptoms mimicking acute infarction without relevant electrocardiographic and biochemical markers of myocardial damage changes. Stressful events inducing an excess catecholamine release and myocardial β-adrenergic receptors (β-AR) seem to play a major role in TT. Ac…

Identificazione di nuovi bersagli terapeutici nel microambiente nei Linfomi T Epatosplenici

Characterization and Evaluation of Hydrothermal Liquefaction Char from Alkali Lignin in Subcritical Temperatures.

2021

An evaluation of hydrothermal liquefaction (HTL) char is investigated in this work. Morphological studies, N2 adsorption behavior, FTIR analysis, thermal behavior, and elemental composition are studied. The HTL char yield showed an increase with higher operating temperatures. It increased from 11.02% to 33% when the temperature increased from 573 K to 623 K. At lower temperatures, the residence time showed an impact on the yield, while close to the critical point, residence time became less impactful. Elemental analysis showed that both higher operating temperatures and longer residence times increased the nitrogen content of the chars from 0.32% to 0.51%. FTIR analysis suggested the char b…

Differential evolution of PSA-NCAM expression during aging of the rat telencephalon

2007

Changes in the ability of neuronal networks to undergo structural remodeling may be involved in the age-associated cognitive decline. The polysialylated form of the neural cell adhesion molecule (PSA-NCAM) declines dramatically during postnatal development, but persists in several regions of the young-adult rat telencephalon, where it participates, through its anti-adhesive properties, in neuronal structural plasticity. However, PSA-NCAM expression during aging has only been studied in the dentate gyrus and the piriform cortex layer II, where it is strongly downregulated in adult (middle-aged) individuals. Using immunohistochemistry, we have observed that in most of the telencephalic areas …

Comparative studies of the Pschorr reaction in the pyrazole series. Access to the new dibenzo[e,g]pyrazolo[1,5-a][1,3]diazocine system of pharmaceuti…

2008

The diazonium tetrafluoroborate 11 obtained from 2-amino-N-methyl-N-(1-phenyl-3- methylpyrazol-5-yl)benzamide was transformed in dry acetonitrile via an ionic or radical pathway. Differences were observed with respect to ionic or radical transformations in aqueous media of the analogous diazonium hydrogen sulfate 1 derived from the same amine. In acetonitrile solution, the ionic pathway was characterized by an increased yield of 1,4-dimethyl- 3-phenyl-pyrazolo(3,4-c)isoquinolin-5-one 4 and by the formation of its isomer, the new derivative 7,9-dimethyldibenzo(e,g)pyrazolo(1,5-a)(1,3)diazocin-10(9H)-one 12. When the reaction followed a radical pathway, the pyrazolo(3,4-c)isoquinoline derivat…

Thermal Stability and Flame Retardancy of Polypropylene Composites Containing Siloxane-Silsesquioxane Resins

2018

A novel group of silsesquioxane derivatives, which are siloxane-silsesquioxane resins (S4SQ), was for the first time examined as possible flame retardants in polypropylene (PP) materials. Thermal stability of the PP/S4SQ composites compared to the S4SQ resins and neat PP was estimated using thermogravimetric (TG) analysis under nitrogen and in air atmosphere. The effects of the non-functionalized and n-alkyl-functionalized siloxane-silsesquioxane resins on thermostability and flame retardancy of PP materials were also evaluated by thermogravimetry-Fourier transform infrared spectrometry (TG-FTIR) and by cone calorimeter tests. The results revealed that the functionalized S4SQ resins may for…

Facile Fabrication of Natural Polyelectrolyte-Nanoclay Composites: Halloysite Nanotubes, Nucleotides and DNA Study

2020

Complexation of biopolymers with halloysite nanotubes (HNTs) can greatly affect their applicability as materials building blocks. Here we have performed a systematic investigation of fabrication of halloysite nanotubes complexes with nucleotides and genomic DNA. The binding of DNA and various nucleotide species (polyAU, UMP Na2, ADP Na3, dATP Na, AMP, uridine, ATP Mg) by halloysite nanotubes was tested using UV-spectroscopy. The study revealed that binding of different nucleotides to the nanoclay varied but was low both in the presence and absence of MgCl2, while MgCl2 facilitated significantly the binding of longer molecules such as DNA and polyAU. Modification of the nanotubes with DNA an…

Synthesis, Characterization and Sorption Capacity Examination for a Novel Hydrogel Composite Based on Gellan Gum and Graphene Oxide (GG/GO)

2020

A novel hydrogel composite based on gellan gum and graphene oxide (GG/GO) was synthesized, characterized and tested for sorption capacity in this work. The microstructural, thermogravimetric and spectroscopic analysis confirmed the formation of the GG/GO composite. Comparative batch sorption experiments revealed a sorption capacity of the GG/GO composite for Zn (II) ions of approximately 2.3 higher than that of pure GG. The GG/GO composite exhibits a maximum sorption capacity of 272.57 mg/g at a pH of Zn (II) initial solution of 6. Generally, the sorption capacity of the sorbents is approximately 1.5 higher in slightly acidic conditions (pH 6) comparative with that for strong acidic conditi…

Conversion of Organic Dyes into Pigments: Extraction of Flavonoids from Blackberries (Rubus ulmifolius) and Stabilization

2021

The blackberry’s color is composed mainly of natural dyes called anthocyanins. Their color is red–purple, and they can be used as a natural colorant. Anthocyanins are flavonoids, which are products of plants, and their colors range from orange and red to various shades of blue, purple and green, according to pH. In this study, the chemical composition of an extract obtained from blackberries was defined by LC-ESI/LTQOrbitrap/MS in positive and negative ionization mode. Furthermore, we investigated the adsorption process of blackberry extract using several inorganic fillers, such as metakaolin, silica, Lipari pumice, white pozzolan and alumina. The pigments exhibit different colors as a func…

Tunable Structure and Properties of Segmented Thermoplastic Polyurethanes as a Function of Flexible Segment

2019

Segmented thermoplastic polyurethanes (PUs) were synthetized using macrodiols with different functional groups (carbonate, ester, and /or ether) as a segment with a molar mass of 1000 and 2000 g/mol, and 4,4&rsquo