Search results for "44"
showing 10 items of 1507 documents
Scholarly publishing depends on peer reviewers
2018
The peer-review crisis is posing a risk to the scholarly peer-reviewed journal system. Journals have to ask many potential peer reviewers to obtain a minimum acceptable number of peers accepting reviewing a manuscript. Several solutions have been suggested to overcome this shortage. From reimbursing for the job, to eliminating pre-publication reviews, one cannot predict which is more dangerous for the future of scholarly publishing. And, why not acknowledging their contribution to the final version of the article published? PubMed created two categories of contributors: authors [AU] and collaborators [IR]. Why not a third category for the peer-reviewer? published
Microencapsulation of Salmonella-Specific Bacteriophage Felix O1 Using Spray-Drying in a pH-Responsive Formulation and Direct Compression Tableting o…
2019
The treatment of enteric bacterial infections using oral bacteriophage therapy can be challenging since the harsh acidic stomach environment renders phages inactive during transit through the gastrointestinal tract. Solid oral dosage forms allowing site-specific gastrointestinal delivery of high doses of phages, e.g., using a pH or enzymatic trigger, would be a game changer for the nascent industry trying to demonstrate the efficacy of phages, including engineered phages for gut microbiome modulation in expensive clinical trials. Spray-drying is a scalable, low-cost process for producing pharmaceutical agents in dry powder form. Encapsulation of a model Salmonella-specific phage (Myoviridae…
Assessment of the Inter-Batch Variability of Microstructure Parameters in Topical Semisolids and Impact on the Demonstration of Equivalence
2019
Demonstration of similar microstructure is essential for demonstrating the equivalence of generic topical products since the microstructure of semisolids may affect the drug release. The objective of this study was to compare the microstructure-defining physical parameters of different batches of a reference ointment containing calcipotriol and betamethasone (Daivobet 50 µ
Rimodulazioni morfosintattiche latino-romanze in prospettiva sistematica
2013
Conocimiento, traza e ingenio en la arquitectura valenciana del siglo XV
2012
In the last decades historiography of gothic architecture in the Crown of Aragon has focused on buildings monographs, documentary research and technical change in stone building. On the other hand, historians of technology have given special attention to the issue of innovation and its diffusion in the late Middle Ages, considering building techniques as a particular field of research. This essay studies transmission of technical knowledge in building trades in order to explain architectural changes in an outstanding environment of innovation such as the kingdom of Valencia in the 14th and 15th centuries, especially from 1430 onwards. Having account of previous research and some cases of st…
Konfliktinjälkeiset kulttuuriympäristöt, muisti ja materiaalisuus
2016
Pohjoisia sota-ajan muistoja käsittelevässä traumaromaanissa Pahan morsian (Ritva-Kaija Laitinen, 1986) teoksen päähenkilö Laura muistelee jatkosodanaikaista rakkauttaan saksalaissotilaaseen. Laura palaa paikalle, johon rakastettu oli vuosikymmeniä aiemmin kaivertanut molempien nimikirjoitukset. Saksan armeijan rakentaman tähystystornin jäänteissä on edelleen useita kaiverruksia, mutta rakastavaisten nimiä Laura ei onnistu sieltä löytämään. On kuin materiaalisuus olisi pettänyt muistin. Materia, sen paremmin kuin mikään muukaan Lauran ympärillä, ei näytä tukevan hänen tarinansa kertomista. Traumatisoituneen yksilön kamppailu menneisyyden prosessoimiseksi rinnastuu teoksessa näin toisen maai…
El sepulcro del Venerable Domingo Anadón en el convento de Santo Domingo de Valencia (1609), obra genovesa encargo del Conde de Benavente = The Tomb …
2020
El presente texto confirma que el monumento funerario encargado en 1609 por Juan Alfonso Pimentel, conde-duque de Benavente a los genoveses Giuseppe Carlone y Oberto Casella fue para la sepultura del fraile Domingo Anadón en el convento de Santo Domingo de Valencia. Se analizan las vicisitudes de este sepulcro junto al de fray Juan Micó en la capilla de San Luis Beltrán del convento, en el marco de la llegada de piezas genovesas a España en época Moderna.AbstractThis text confirms that the funerary monument commissioned in 1609 by Juan Alfonso Pimentel, count-duke of Benavente to the genoese sculptors Giuseppe Carlone and Oberto Casella was for friar Domingo Anadon in the dominican convent …
Struggles for moral value and the reproduction of gendered and racialised hierarchies in online discussions of violence
2019
The article examines online discussions in Finland that focus on violence committed by Finnish women, on one hand, and non-white migrant men, on the other. Drawing on the perspective of sociology of value, the article illustrates how these discussions function as sites of struggles over moral worth in a contemporary context characterised by crises of both male and white hegemony. The authors suggest that, through the discussions, these current crises are projected on migrant men and certain groups of women, who thereby become construed as morally reprehensible. The analysis sheds light on processes of (re-)legitimating the moral virtue historically attached to both masculinity and whitenes…
La dialisi peritoneale nella realtà lavorativa degli uremici in trattamento sostitutivo. Nota II
2009
Blends of Semiflexible Polymers: Interplay of Nematic Order and Phase Separation
2021
Mixtures of semiflexible polymers with a mismatch in either their persistence lengths or their contour lengths are studied by Density Functional Theory and Molecular Dynamics simulation. Considering lyotropic solutions under good solvent conditions, the mole fraction and pressure is systematically varied for several cases of bending stiffness κ (the normalized persistence length) and chain length N. For binary mixtures with different chain length (i.e., NA=16, NB=32 or 64) but the same stiffness, isotropic-nematic phase coexistence is studied. For mixtures with the same chain length (N=32) and large stiffness disparity (κB/κA=4.9 to 8), both isotropic-nematic and nematic-nematic unmixing oc…