Search results for "44"
showing 10 items of 1507 documents
Easy access to heterobimetallic complexes for medical imaging applications via microwave-enhanced cycloaddition
2015
The Cu(I)-catalysed Huisgen cycloaddition, known as “click” reaction, has been applied to the synthesis of a range of triazole-linked porphyrin/corrole to DOTA/NOTA derivatives. Microwave irradiation significantly accelerates the reaction. The synthesis of heterobimetallic complexes was easily achieved in up to 60% isolated yield. Heterobimetallic complexes were easily prepared as potential MRI/PET (SPECT) bimodal contrast agents incorporating one metal (Mn, Gd) for the enhancement of contrast for MRI applications and one “cold” metal (Cu, Ga, In) for future radionuclear imaging applications. Preliminary relaxivity measurements showed that the reported complexes are promising contrast agent…
Naringenin Nano-Delivery Systems and Their Therapeutic Applications
2021
Naringenin (NRG) is a polyphenolic phytochemical belonging to the class of flavanones and is widely distributed in citrus fruits and some other fruits such as bergamot, tomatoes, cocoa, and cherries. NRG presents several interesting pharmacological properties, such as anti-cancer, anti-oxidant, and anti-inflammatory activities. However, the therapeutic potential of NRG is hampered due to its hydrophobic nature, which leads to poor bioavailability. Here, we review a wide range of nanocarriers that have been used as delivery systems for NRG, including polymeric nanoparticles, micelles, liposomes, solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), nanosuspensions, and nano…
Alocución pronunciada en el acto de la solemne inauguración de la calle dedicada al excelentisimo señor Don Juan Navarro Reverter, en la ciudad de Se…
Origen y estatus social de las religiosas del Señorío de Vizcaya durante la Edad Moderna
2018
The Participation of 3,3,3-Trichloro-1-nitroprop-1-ene in the [3 + 2] Cycloaddition Reaction with Selected Nitrile N-Oxides in the Light of the Exper…
2021
The regioselective zw-type [3 + 2] cycloaddition (32CA) reactions of a series of aryl-substituted nitrile N-oxides (NOs) with trichloronitropropene (TNP) have been both experimentally and theoretically studied within the Molecular Electron Density Theory (MEDT). Zwitterionic NOs behave as moderate nucleophiles while TNP acts as a very strong electrophile in these polar 32CA reactions of forward electron density flux, which present moderate activation Gibbs free energies of 22.8–25.6 kcal·mol−1 and an exergonic character of 28.4 kcal·mol−1 that makes them irreversible and kinetically controlled. The most favorable reaction is that involving the most nucleophilic MeO-substituted NO. Despite P…
Metal-Organic Frameworks as Versatile Heterogeneous Solid Catalysts for Henry Reactions
2021
Metal–organic frameworks (MOFs) have become one of the versatile solid materials used for a wide range of applications, such as gas storage, gas separation, proton conductivity, sensors and catalysis. Among these fields, one of the more well-studied areas is the use of MOFs as heterogeneous catalysts for a broad range of organic reactions. In the present review, the employment of MOFs as solid catalysts for the Henry reaction is discussed, and the available literature data from the last decade are grouped. The review is organized with a brief introduction of the importance of Henry reactions and structural properties of MOFs that are suitable for catalysis. The second part of the review dis…
Restricting Magnetic Interaction Pathways in Polyoxometalate Salts of Cationic Nitronyl Nitroxide Free Radicals
2004
Abstract : Salts 1 and 2 that combine the [W 6 O 19 ] 2- Lindqvist anion with the cationic nitronyl nitroxide (NN) free radicals p -MepyNN + and n Bu 3 NCH 2 NN + , respectively, have been synthesized and their structural and magnetic properties have been studied. Keywords: Nitroxide radicals, polyoxometalates, magnetism. Introduction Ferromagnetism based on purely organic materials has raised a lot of interest during the last decade [1]. Most of the studies have been performed with nitronyl nitroxide (NN) radicals due to their persistence, stability and ease of functionalization [2]. Bulk ferromagnetism in these compounds arises from ferromagnetic interactions between open-shell molecules …
Marie Mennessier-Nodier, récits et nouvelles
2019
International audience
"2/NPART*" of "Centrality and pseudorapidity dependence of the charged-particle multiplicity density in Xe-Xe collisions at $\sqrt{s_{\rm NN}}$ = 5.4…
2019
Values of $2/\langle N_\mathrm{part} \rangle \langle \mathrm{d}N_\mathrm{ch}/\mathrm{d}\eta\rangle$ and $2/\langle N_\mathrm{part} \rangle N^\mathrm{tot}_\mathrm{ch}$ in Xe--Xe collisions at $\sqrt{s_{_{\mathrm{NN}}}} = 5.44\,\mathrm{TeV}$ for the top 5$\%$ central collisions.
"2/NPART*_VS_SCALED" of "Centrality and pseudorapidity dependence of the charged-particle multiplicity density in Xe-Xe collisions at $\sqrt{s_{\rm N…
2019
Values of $2/\langle N_\mathrm{part} \rangle \langle \mathrm{d}N_\mathrm{ch}/\mathrm{d}\eta\rangle$ and $2/\langle N_\mathrm{part} \rangle N^\mathrm{tot}_\mathrm{ch}$ as a function of $(\langle N_\mathrm{part} \rangle -2)/(2A)$ in Xe--Xe collisions at $\sqrt{s_{_{\mathrm{NN}}}} = 5.44\,\mathrm{TeV}$.