Search results for "44"
showing 10 items of 1507 documents
Antioxidant Bibenzyl Derivatives from Notholaena nivea Desv.
2011
Four new bibenzyl derivatives were isolated, together with other known bibenzyls, by bioassay-guided fractionation of a CHCl3-MeOH extract of Notholaena nivea Desv. (Pteridaceae) aerial parts. The structures were elucidated by NMR, ESIMS and other spectral analyses. Their antioxidative effects towards superoxide, lipidic peroxidation and the 2,2'- azino-bis-3- ethilbenzothiazoline-6-sulfonic acid (ABTS) radical were assayed. Results showed that the compound 3,12-dihydroxy-5-methoxybibenzyl (6) is the most active compound in the ABTS free-radical scavenging test, while in the coupled oxidation of ȕ-carotene and linoleic acid assay the compound 5,12-dihydroxy-3-methoxydibenzyl-6- carboxylic a…
Aza- and Azo-Stilbenes: Bio-Isosteric Analogs of Resveratrol
2020
Several series of natural polyphenols are described for their biological and therapeutic potential. Natural stilbenoid polyphenols, such as trans-resveratrol, pterostilbene and piceatannol are well-known for their numerous biological activities. However, their moderate bio-availabilities, especially for trans-resveratrol, prompted numerous research groups to investigate innovative and relevant synthetic resveratrol derivatives. This review is focused on isosteric resveratrol analogs aza-stilbenes and azo-stilbenes in which the C=C bond between both aromatic rings was replaced with C=N or N=N bonds, respectively. In each series, synthetic ways will be displayed, and structural sights will be…
Phytochemical Studies on Ptilostemon greuteri Raimondo & Domina (Compositae)
2012
Ptilostemon greuteri Raimondo & Domina is described as a new species and its growth is limited to the area of the province of Trapani. Essential oils of aerial parts of P. greuteri were analized by gas chromatography-mass spectrometry (GC-MS). The analysis of acetonic extract of aerial parts led to identification of triterpenes components: α-amyrin, β-amyrin, α-amyrin acetate, β-amyrin acetate, lupeol, lupeol acetate and taraxasterol. CC and preparative TLC of acetonic extracts has yielded lignan lactone and a sesquiterpene lactone that have been isolated previously from other Ptilostemon species.
Endeudamiento municipal en la región de Lleida a finales del siglo XVII
2018
Este articulo quiere analizar la evolución del endeudamiento de los municipios de la región económica de Lleida a finales del siglo XVII para poner de relieve no solo el enorme peso que este tuvo sobre los municipios catalanes de los siglos modernos, sino también el efecto que causó la expansión económica de los años previos a la guerra de Sucesión sobre esta deuda. Durante los años estudiados hemos podido observar una mejora evidente sobre el nivel de endeudamiento comunal, pero también la persistencia de problemas crónicos en las finanzas municipales. In this paper is analyzed the municipal debt evolution of the Lleida region during the late seventeenth century. It highlights the importan…
Contribution of bronchial biopsies in the evaluation of pathogenesis and progression of COPD.
2016
This review summarizes and discusses the lung pathology of COPD patients emphasising on inflammatory cell phenotypes and mechanisms which prevail in different clinical conditions. In bronchial biopsies a series of events takes place during the progression of the disease from mild to severe. T-lymphocytes, particularly CD8+ cells and macrophages are the prevalent inflammatory cells in the lungs of healthy smokers and patients with mild/moderate COPD. This T-cell activation seems to be sustained by CD4+, CD8+ cells and macrophages expressing transcription factors and Tc1 cytokines such as NF-kB, STAT4 and IFNγ. In contrast, severe disease is characterized by lymphocytes producing greater amo…
Unique continuation property and Poincar�� inequality for higher order fractional Laplacians with applications in inverse problems
2020
We prove a unique continuation property for the fractional Laplacian $(-\Delta)^s$ when $s \in (-n/2,\infty)\setminus \mathbb{Z}$. In addition, we study Poincar\'e-type inequalities for the operator $(-\Delta)^s$ when $s\geq 0$. We apply the results to show that one can uniquely recover, up to a gauge, electric and magnetic potentials from the Dirichlet-to-Neumann map associated to the higher order fractional magnetic Schr\"odinger equation. We also study the higher order fractional Schr\"odinger equation with singular electric potential. In both cases, we obtain a Runge approximation property for the equation. Furthermore, we prove a uniqueness result for a partial data problem of the $d$-…
Fourier analysis of periodic Radon transforms
2019
We study reconstruction of an unknown function from its $d$-plane Radon transform on the flat $n$-torus when $1 \leq d \leq n-1$. We prove new reconstruction formulas and stability results with respect to weighted Bessel potential norms. We solve the associated Tikhonov minimization problem on $H^s$ Sobolev spaces using the properties of the adjoint and normal operators. One of the inversion formulas implies that a compactly supported distribution on the plane with zero average is a weighted sum of its X-ray data.
Selective versions of chain condition-type properties
2015
We study selective and game-theoretic versions of properties like the ccc, weak Lindel\"ofness and separability, giving various characterizations of them and exploring connections between these properties and some classical cardinal invariants of the continuum.
Pharmaceutical potential of synthetic and natural pyrrolomycins
2015
The emergence of antibiotic resistance is currently considered one of the most important global health problem. The continuous onset of multidrug-resistant Gram-positive and Gram-negative bacterial strains limits the clinical efficacy of most of the marketed antibiotics. Therefore, there is an urgent need for new antibiotics. Pyrrolomycins are a class of biologically active compounds that exhibit a broad spectrum of biological activities, including antibacterial, antifungal, anthelmintic, antiproliferative, insecticidal, and acaricidal activities. In this review we focus on the antibacterial activity and antibiofilm activity of pyrrolomycins against Gram-positive and Gram-negative pathogens…
Conformational and Tautomeric Control by Supramolecular Approach in Ureido-N-iso-propyl,N’-4-(3-pyridin-2-one)pyrimidine
2019
Ureido-N-iso-propyl,N&rsquo