Search results for "45"

showing 10 items of 1896 documents

Metabolic response to 6-week aerobic exercise training and dieting in previously sedentary overweight and obese pre-menopausal women: A randomized tr…

2014

AbstractBackground: The aim of this study was to compare 6 weeks short-term moderate intensity aerobic exercise and dieting on serum metabolomicsand cardio-metabolic risk factors in pre-menopausal women.Methods: Ninety previously inactive overweight and obese (BMI 25e35 kg/m 2 ) women (age 41.5 7.6 years) were randomized to either a6-week Nordic walking exercise program (EX, n ¼ 45) or dietary counseling group (DI, n ¼ 45). Body composition, serum glucose, insulin andlipids were measured. Serum low-molecular-weight metabolites and lipid constituents were analyzed by nuclear magnetic resonance spec-troscopy. Measurements were done at baseline and 7 days after the last training session.Result…

medicine.medical_specialtymedicine.medical_treatmentDietingPhysical Therapy Sports Therapy and RehabilitationOverweightlaw.inventionlcsh:GV557-1198.995Insulin resistanceRandomized controlled trialWeight losslawInternal medicinemedicineMetabolomicsAerobic exerciseWomenOrthopedics and Sports Medicinelcsh:Sports medicineExerciselcsh:Sportsbusiness.industryInsulinta3141Metabolismmedicine.diseaseMetabolismEndocrinologymedicine.symptomlcsh:RC1200-1245businessDietingJournal of Sport and Health Science
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Tobacco smoking and risk of endometriosis: a systematic review and meta-analysis

2014

Objective Since conflicting results have been published on the role of tobacco smoking on the risk of endometriosis, we provide an up-to-date summary quantification of this potential association. Design We performed a PubMed/MEDLINE search of the relevant publications up to September 2014, considering studies on humans published in English. We searched the reference list of the identified papers to find other relevant publications. Case–control as well as cohort studies have been included reporting risk estimates on the association between tobacco smoking and endometriosis. 38 of the 1758 screened papers met the inclusion criteria. The selected studies included a total of 13 129 women diagn…

medicine.medical_specialtymedicine.medical_treatmentEndometriosisMEDLINEEndometriosisGlobal HealthRisk FactorsInternal medicineEpidemiologyObstetrics and Gynaecologymedicine1845EPIDEMIOLOGYHumans1506Gynecologybusiness.industry1731Risk FactorResearchSmokingGeneral MedicineGYNAECOLOGYFormer Smokermedicine.diseaseSettore MED/40 - Ginecologia E Ostetricia1692Relative riskMeta-analysisSmoking cessation1734FemaleSmoking CessationMorbiditybusinessCohort studyHumanBMJ Open
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Effect of aerobic exercise on insulin resistance and central adiposity disappeared after the discontinuation of intervention in overweight women

2016

Purpose: This study aimed to assess whether the benefits of exercise on central adiposity and insulin resistance (HOMA-IR) are maintained after discontinuation of intervention in the overweight/obese (OWOB) women. Methods: The study subjects were from 2 independent studies with similar aerobic exercise (AE) intervention programs. In study I, 15 OWOB postmenopausal women with pre-diabetes (body mass index, BMI = 24–33 kg/m2 , aged 52–65 years) completed an 8-month exercise intervention and were followed for 2 years after the intervention. In study II, 12 OWOB (BMI = 25–35 kg/m2 , aged 30–50 years) premenopausal women participated in a 6-week AE and were followed for 4 years after the interve…

medicine.medical_specialtypremenopause030209 endocrinology & metabolismPhysical Therapy Sports Therapy and RehabilitationOverweight03 medical and health scienceslcsh:GV557-1198.9950302 clinical medicineInsulin resistanceIntervention (counseling)medicineAerobic exerciseta319Exercise interventionOrthopedics and Sports MedicineSpecial issue on "Physical activity continuum throughout the lifespan: is exercise a medicine or what?"030212 general & internal medicineObesityexercise interventionRelapselcsh:Sports medicineta315lcsh:SportsExercise interventionrelapsibusiness.industrynutritional and metabolic diseasesmedicine.diseaseObesityDiscontinuationPostmenopausepostmenopausePremenopausePhysical therapyCentral Adipositylihavuusmedicine.symptombusinesslcsh:RC1200-1245Journal of Sport and Health Science
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Reliability and validity of time domain heart rate variability during daily rout¡ne activities : an alternative to the morning orthostatic test?

2017

Summary Study aim: To determine the reliability and validity of a time domain heart rate variability (HRV) index during free-living physical activity (FLPA). Material and methods: Eight white-collar workers participated in this study. RR intervals (time between consecutive R-peaks of the PQRS complex) were recorded using the Polar V800 heart rate (HR) monitor upon awakening and at work on 16 different days. A total of 127 cycles of sitting periods followed by walking breaks were included for consecutive pairwise analysis for reliability. The HR values from the orthostatic test (OT) were compared with the corresponding values at work. Results: The HR values showed high levels of repeatabilit…

medicine.medical_specialtyvalidityPhysiologyPhysical Therapy Sports Therapy and Rehabilitationmonitorointi030204 cardiovascular system & hematology03 medical and health sciencesrecovery0302 clinical medicinemedicineHeart rate variabilityQP1-981Orthopedics and Sports MedicineTime domainDaily routineReliability (statistics)MorningreliabilityPublic healthrmssd030229 sport sciencesOrthostatic testmonitoringRMSSDvaliditeettiSports medicinePhysical therapyPsychologyRC1200-1245
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Clinical implications ofCYP3Apolymorphisms

2006

Due to their enormous substrate spectrum CYP3A4, -3A5 and -3A7 constitute the most important drug-metabolising enzyme subfamily in humans. CYP3As are expressed predominantly, but not exclusively, in the liver and intestine, where they participate in the metabolism of 45 - 60% of currently used drugs and many other compounds such as steroids and carcinogens. CYP3A expression and activity vary interindividually due to a combination of genetic and nongenetic factors such as hormone and health status, and the impact of environmental stimuli. Over the past several years, genetic determinants have been identified for much of the variable expression of CYP3A5 and -3A7, but not for CYP3A4. Using th…

medicine.medical_treatmentBiologyToxicologyBioinformatics030226 pharmacology & pharmacyGene Expression Regulation EnzymologicTacrolimusVariable Expression03 medical and health sciencesProstate cancer0302 clinical medicinemedicineCytochrome P-450 CYP3AHumansCYP3A5PharmacologyRegulation of gene expressionGeneticsPolymorphism GeneticCYP3A4General Medicinemedicine.diseaseTacrolimus3. Good healthIsoenzymesImmunosuppressive drug030220 oncology & carcinogenesisCyclosporineImmunosuppressive AgentsPharmacogeneticsExpert Opinion on Drug Metabolism & Toxicology
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Regulation of cytochrome P450 IID by acute phase mediators in C3H/HeJ mice.

1992

Abstract Cytochrome P450 IID6 is a drug metabolizing enzyme and the major target antigen in LKM-1 antibody positive chronic active hepatitis. The histological hallmark of chronic active hepatitis is a lymphocytic infiltrate in the liver. It is unknown whether and how cytokines produced and secreted by these tissue infiltrating mononuclear cells regulate the cellular expression of cytochrome P450 IID6. To study the effect of interleukin 1, tumor necrosis factor and interleukin 6 on the hepatocellular RNA expression of cytochrome P450 IID, we injected each of the cytokines in C3H HeJ mice. We found a time-dependent suppression of the cytochrome in the liver. Six hours after the intraperitonea…

medicine.medical_treatmentIntraperitoneal injectionBiophysicsBiochemistryMixed Function OxygenasesMiceCytochrome P-450 Enzyme SystemmedicineEscherichia coliAnimalsHumansInterleukin 6Molecular BiologyHepatitisMice Inbred C3HbiologyInterleukin-6Tumor Necrosis Factor-alphaCytochrome P450InterleukinCell Biologymedicine.diseaseBlotting NorthernRecombinant ProteinsEndotoxinsCytokineCytochrome P-450 CYP2D6LiverImmunologybiology.proteinRNATumor necrosis factor alphaFemaleAntibodyInterleukin-1Biochemical and biophysical research communications
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The Effect of 16-Minute Thermal Stress and 2-Minute Cold Water Immersion on the Physiological Parameters of Young Sedentary Men

2020

This study aimed to determine the effect of 16 minutes of thermal stress followed by 2 minutes of cold water immersion on the physiological parameters of fifty-five sedentary men (mean age 20.15±1.30 years), who were exposed to 16 minutes of sauna (temperature: 90-91℃; relative humidity: 14-16%) followed by 2 minutes of cold water immersion (12℃). The participants' somatic characteristics were determined before entering the sauna, and their body mass and blood pressure were measured before and after sauna treatment. Physiological parameters were monitored during the 16-minute sauna session and the 2-minute cold water immersion (CRIO) or shower. The subjects perspired 0.21-0.27 litres during…

medicine.medical_treatmentsaunominenPhysical Therapy Sports Therapy and RehabilitationCryotherapysomatic featuresAnimal sciencelämpöhoitosedentary menphysiological parametersmedicineOrthopedics and Sports Medicinekylmähoitokehonkoostumusbody compositionbusiness.industryRehabilitationarchitecture.styleFinnish saunafinnish saunaarchitectureWater immersionFinnish SaunaGV557-1198.995Sports medicinemiehetbusinesscryotherapyRC1200-1245fysiologiset vaikutuksetSportsMontenegrin Journal of Sports Science and Medicine
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Les vicissituds de la traducció al castellà d’elements heroics i medievals del Canigó, de Jacint Verdaguer. El cas de «La Maladeta»

2014

Resum: En aquest article s’estudien les dificultats de traduir «La Maladeta», un passatge de Canigó, de Jacint Verdaguer. Creiem que aquest fragment és prou representatiu de la temàtica del poema èpic verdaguerià, ja que ha estat un dels més traduïts a totes les llengües i, a més, conté elements heroics i medievals del poema. És per això que hem cregut oportú de fer l’anlàlisi de la traducció dels fragments, per poder treure’n unes conclusions que ens serveixin per avaluar la qualitat de cada versió.Paraules clau: Verdaguer, Canigó, medieval, traducció. Abstract: In this article we study the translation’s difficulties of «La Maladeta», an extract of Canigó by Jacint Verdaguer. We think that…

medievalHistoryLiterature and Literary Theorymedia_common.quotation_subjectlcsh:Literature (General)lcsh:D111-203lcsh:Medieval historytraduccióArtEPICVerdaguerlcsh:PN1-6790Language and Linguisticslcsh:D204-475CanigóHumanitiesmedia_commonlcsh:Modern history 1453-Scripta: Revista Internacional de Literatura i Cultura Medieval i Moderna
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Josefa Verride y Martina de los Ángeles. El difícil camino hacia la santidad.

2016

Resumen: A través de la información que nos proporcionan las vidas de Josefa Verride, tercera de la orden dominica en Huesca y Martina de los Ángeles, religiosa de la misma orden, fundadora del convento de san Pedro de Benabarre, pretendo aportar nuevas ideas acerca del proceso de adquisición de la fama de santidad de algunas mujeres en la Edad Moderna española. Las órdenes religiosas debieron idear estrategias que ayudasen a legitimar y consolidar la fama de santidad de estas mujeres. Una de estas estrategias fue la vinculación de las religiosas con otras mujeres con fama de santidad, creando genealogías femeninas que les permitiesen perpetuar su memoria y prestigio a lo largo del tiempo. …

memoriaHistoryLiterature and Literary TheoryFilologíasmedia_common.quotation_subjectlcsh:Literature (General)lcsh:D111-203santidad femeninalcsh:Medieval historySisterLanguage and LinguisticsMartina de los Ángelesgenealogías femeninasSociologyOrder (virtue)Josefa Verridemedia_commonUNESCO::CIENCIAS DE LAS ARTES Y LAS LETRASPrestigeFilologías. Generalidadeslcsh:PN1-6790lcsh:D204-475:CIENCIAS DE LAS ARTES Y LAS LETRAS [UNESCO]Humanitieslcsh:Modern history 1453-Reputation
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Autobiografía y memoria en el diario de viajes del VI Conde de Fernán Núñez = Autobiography and Memory in the Travel Diary of the VI Count of Fernán …

2016

ResumenEl viaje fue una constante en la vida de don Carlos José Gutiérrez de los Ríos, VI conde de Fernán Núñez (1742-1795). A través de ellos pudo cumplir con su servicio al rey y con sus responsabilidades como cabeza del linaje. Asimismo pudo completar su formación y satisfacer anhelos más personales. De todos sus viajes, los realizados dentro y fuera de España, guardó memoria escrita en un diario de viajes, un documento que, en formato manuscrito, se conservó en su archivo familiar. En un periodo cronológico en el que el viaje y su relato adquirieron especial protagonismo, este trabajo analiza el papel que el viaje jugó en la vida y memoria del VI conde de Fernán Núñez y su impronta dent…

memorialcsh:History (General) and history of Europemedia_common.quotation_subjectsiglo XVIII = Travel diarieslinajeArtlcsh:History (General)lcsh:D1-2009VI Count of Fernán Núñezmemory18th Century.lcsh:Dlcsh:D204-475Diario de viajesHumanitiesmedia_commonVI Conde de Fernán Núñezlineagelcsh:Modern history 1453-Espacio, Tiempo y Forma. Serie IV, Historia Moderna
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