Search results for "45"
showing 10 items of 1896 documents
Vēsture: Latvijas Universitātes Žurnāls, 3
2017
https://doi.org/10.22364/luzv.3.2017
Automated Determination of Paroxetine and Its Main Metabolite by Column Switching and On-Line High-Performance Liquid Chromatography
1994
An automated column-switching method coupled to isocratic high-performance liquid chromatography has been developed for simultaneous determination of blood levels of paroxetine and its nonconjugated main metabolite BRL 36610. The lower limits of detection were 9-15 nmol/L (3-5 ng/ml) and linearity between drug concentration and detector response was found for 0-1,500 nmol/L (0-500 ng/ml). The method could be applied to the analysis of serum samples obtained from depressed patients who were treated with daily oral doses of 20 or 40 mg of paroxetine. After the 20-mg dose, the mean blood level of paroxetine was 69 nM (23 ng/ml), whereas the metabolite BRL 36610 was detectable in only one of 5 …
In silico methods for metabolomic and toxicity prediction of zearalenone, α-zearalenone and β-zearalenone.
2020
Zearalenone (ZEA), α-zearalenol (α-ZEL) and β-zearalenol (β-ZEL) (ZEA's metabolites) are co/present in cereals, fruits or their products. All three with other compounds, constitute a cocktail-mixture that consumers (and also animals) are exposed and never entirely evaluated, nor in vitro nor in vivo. Effect of ZEA has been correlated to endocrine disruptor alterations as well as its metabolites (α-ZEL and β-ZEL); however, toxic effects associated to metabolites generated once ingested are unknown and difficult to study. The present study defines the metabolomics profile of all three mycotoxins (ZEA, α-ZEL and β-ZEL) and explores the prediction of their toxic effects proposing an in silico w…
A Cross-Sectional Study on the Prevalence and Incidence of Pressure Ulcers in an Italian University Hospital-Umbria Region
2020
Objective: The aim of the present study was to assess the prevalence and incidence of pressure ulcers (PUs) in patients hospitalized in a University Hospital in central Italy. Methods: We carried out a prevalence and incidence study on PUs and an additional prevalence estimate of PUs was also produced ten days after the first assessment. All data were explored by descriptive statistics, the Chi-square test and a multivariate analysis. Results: The prevalence of pressure ulcers was of 6,5%, while it increased to 9,9% at the second assessment ten days after the first measurement. Prevalence was statistically significant and increased with the age of inpatients (p=0,004) and was correlated to …
"Table 2" of "The Ratio of isolated photon cross-sections at s**(1/2) = 630-GeV and 1800-GeV"
2003
No description provided.
"Table 3" of "The Ratio of isolated photon cross-sections at s**(1/2) = 630-GeV and 1800-GeV"
2003
No description provided.
[Edicte, 1746, 02, 04]
1746
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Informazione biomedica su Internet e motori di ricerca. Risultati di un trial di un anno
2004
The internet is a communication medium and content distributor that provide information in the general sense but it could be of great utility regarding as the search and retrieval of biomedical information. Search engines represent a great deal to rapidly find information on the net. However, we do not know whether general search engines and meta-search ones are reliable in order to find useful and validated biomedical information. The aim of our study was to verify the reproducibility of a search by key-words (pediatric or evidence) using 9 international search engines and 1 meta-search engine at the baseline and after a one year period. We analysed the first 20 citations as output of each…
Representation of physical activity domains and sedentary behaviors across categories of gender and disability in children’s TV cartoons
2018
Television (TV) cartoons could reflect and shape social values about children’s health-related behaviors. The main aim of this study is to analyze the portrayal of physical activity (PA) domains in the most popular Spanish children’s television (TV) cartoons. It is performed a content analysis of each scene following a coding scheme. The sample selected included the five most popular children’s TV cartoons for the 2013-2014 period in Spain. Our results show a large gap between the modest representation of different PA domains compared to the overwhelming depiction of sedentary behaviors. We do not find evidence of males and females participating equally in a variety of PA domains, and we fa…