Search results for "47"

Assessment of computational methods for the analysis of single-cell ATAC-seq data

2019

Abstract Background Recent innovations in single-cell Assay for Transposase Accessible Chromatin using sequencing (scATAC-seq) enable profiling of the epigenetic landscape of thousands of individual cells. scATAC-seq data analysis presents unique methodological challenges. scATAC-seq experiments sample DNA, which, due to low copy numbers (diploid in humans), lead to inherent data sparsity (1–10% of peaks detected per cell) compared to transcriptomic (scRNA-seq) data (10–45% of expressed genes detected per cell). Such challenges in data generation emphasize the need for informative features to assess cell heterogeneity at the chromatin level. Results We present a benchmarking framework that …

Existence and uniqueness of solution to several kinds of differential equations using the coincidence theory

2015

The purpose of this article is to study the existence of a coincidence point for two mappings defined on a nonempty set and taking values on a Banach space using the fixed point theory for nonexpansive mappings. Moreover, this type of results will be applied to obtain the existence of solutions for some classes of ordinary differential equations. Ministerio de Economía y Competitividad Junta de Andalucía

El management de las conductas socioemocionales. Una aproximación teórica y empírica desde el caso de los agentes de "contact centers"

2020

How is a specific type of emotion-related work conducts formed today? What principles guide these conducts and what effects do they have on those who work? The study of Contact Center agents allows us to understand how a set of personal qualities such as patience and good treatment of others, certain desires and personal impulses or even intimate sensations such as anguish or individual expectations have become managerialized emotions that end up modifying the inner attitudes of these agents. Within this framework, we propose a theoretical approach that integrates the work of Weber, Foucault and Elias, which invites us to reflect on a socio-emotional manner of leading one?s life (Lebensfu?h…

Prípiat o el Sol: en diálogo con la propuesta ecosicialista de Joaquim Sempere

2019

Quaestio : Vtrùm Sacratissima Virgo Senensis Catharina Ordinis Praedicatorum possit depingi cum Stigmatibus? / Authore R. P. M. Fr. Ioanne Martinez …

1652

Escut dels dominicans al final Bandes, caplletra ornada Sign.: A8 Text a dues col. Reclams

The economic impact of migration: productivity analysis for Spain and the UK

2012

Over the past 20 years labour has become increasingly mobile and whilst employment and earnings effects in host countries have been extensively analysed, the implications for firm and industry performance have received far less attention. This paper explores the direct economic consequences of immigration on host nations’ productivity performance at a sectoral level in two very different European countries, Spain and the UK. Whilst the UK has traditionally seen substantial immigration, for Spain the phenomenon is much more recent. Our findings from a growth accounting analysis show that migration has made a negative contribution to labour productivity growth in Spain and a negative but negl…

Robres, Fernando Andrés, Benítez Sanchez-Blanco, Rafael y Ciscar Pallarés, Eugenio: El monasterio rebelde. Monarquía y poder monástico en reinode Val…

2021

R&D Offshoring and the Productivity Growth of European Regions

2013

The recent increase in R&D offshoring have raised fears that knowledge and competitiveness in advanced countries may be at risk of `hollowing out\'. At the same time, economic research has stressed that this process is also likely to allow some reverse technology transfer and foster growth at home. This paper addresses this issue by investigating the extent to which R&D offshoring is associated with productivity dynamics of European regions. We find that offshoring regions have higher productivity growth, but this positive effect fades down with the number of investment projects carried out abroad. A large and positive correlation emerge between the extent of R&D offshoring and the home reg…

Thermoeconomic optimization of a renewable polygeneration system serving a small isolated community

2015

During the last years, special attention has been paid to renewable polygeneration technologies, able of simultaneously producing thermal, cooling, electrical energy and desalinated water from seawater. This paper focuses on an innovative polygeneration system driven by renewable energy sources, including the following technologies: hybrid photovoltaic/thermal collectors, concentrating parabolic trough (CPVT), a biomass heater, a single-stage absorption chiller and a multiple-effect distillation desalination system. The system is designed to cover the base load of an isolated small community. In previous papers, the dynamic simulation model about plant operation is discussed. In this paper,…

Rentabilidad de una pequeña explotación agraria en Vall de Uxó, 1721-1739

1982

Una serie de circunstancias nos ha permitido conocer la contabilidad de una pequeña explotación en la llanura costera valenciana, en Vall de Uxó, límite sur de la actual provincia de Castellón. En un proceso típico los arrendatarios de los derechos señoriales del Ducado de Villahermosa no pueden hacer frente a sus pagos y sus tierras son confiscadas; la cosecha está por recoger y se conceden temporalmente en administración a un campesino del lugar. Al no surgir postores en las subastas que se realizan, parte de las tierras siguen en manos de este labrador, a quien un buen día se le exigen cuentas de su administración. La relación pormenorizada de los gastos que ha realizado en el cultivo de…