Search results for "52"
showing 10 items of 1043 documents
Changes in health-related quality of life in elderly men after 12 weeks of strength training
2017
Background Muscular strength is associated with functional ability in elderly, and older adults are recommended to perform muscle-strengthening exercise. Understanding how improved muscle strength and -mass influence general and specific domains of quality of life is important when planning health promotion efforts targeting older adults. The aims of the present study were to describe changes in health-related quality of life (HRQOL) in older men participating in 12 weeks of systematic strength training, and to investigate whether improvements in muscle strength and muscle mass are associated with enhancements in HRQOL. Methods We recruited 49 men aged 60–81 years to participate in an inter…
The pathophysiology of aging bone jaw: primary and secondary prevention
2010
The skeleton is composed of approximately 200 bones, and it is the backbone of our body along with ligaments and joints. The bone is not a static but a dynamic structure, constantly reshuffling, that may suffer fractures due to trauma, despite their particular hardness and strength. Complex physiologic mechanisms, sometimes with the help of surgery, can lead to bone repairing. In the elderly, often, the skeletal system can be affected by osteoporosis, a "silent disease" that causes fragile bones especially of the vertebrae and femur; its contributing factors are menopause (in women), smoking, nutritional deficiencies, systemic diseases or prolonged use of drugs. The masticatory apparatus an…
Multidimensional health modeling: Association between socioeconomic and psychosocial factors and health in Latvia
2009
This research aims at estimating association between socioeconomic and psychosocial factors on the one hand and health in Latvia on the other hand. While information on association between socioeconomic determinants of population health in Latvia is scarce, effect of psychosocial resources on individual health in this country hasn’t been estimated before. We find empirical support for the association between different psychosocial factors and physical health in Latvia. This paper proposes new approach for modelling self-assessed health. We find that the concept of health is too complicated to measure effects of health determinants using a one-dimensional econometric model. We apply two-dime…
Mortality Risk Assessment at the Admission in Patient With Proximal Femur Fractures: Electrolytes and Renal Function
2021
In patients over 65y.o. who were surgically treated for a hip fracture, electrolytes have not been specifically studied as predictors of mortality. The main purpose of this study was to assess whether electrolytes and chronic kidney disease (CKD) stages, evaluated at admission, could represent a pre-operative prognostic factor in this population. Moreover, the role of epidemiological and clinical parameters was analyzed with and without a surgical timing stratification. This retrospective study included 746 patients. For each patient, their age, gender, fracture classification, Hb value, comorbidities, ASA class, chronic kidney disease, creatinine levels, electrolytes and surgical timing w…
Development of a Parkinson’s disease specific falls questionnaire
2020
Abstract Background Falls are a major health burden for older adults with Parkinson’s disease (PD), but there is currently no reliable questionnaire to capture the circumstances and consequences of falls in older adults with PD. This study aimed to develop a PD-specific falls questionnaire and to evaluate its test-retest reliability in older adults with PD. Methods A novel PD-specific falls questionnaire (PDF-Q) was developed in two modes (online and paper-based version) and used to assess falls and near-falls events over the past 12-months. Questions were agreed upon by an expert group, with the domains based on previous falls-related questionnaires. The questions included the number and c…
COMEPA (COVID-19 Medicina Policlinico Palermo): a study in hospitalized patients
2021
Coronavirus disease 2019 (COVID-19) has dramatically changed our lives. In the past months, hospitals were saturated of patients; therefore, it is still important to have simple and standardized prognostic factors and to evaluate the efficacy and safety of medications commonly used for COVID-19. We aimed to collect data of the patients hospitalized in Internal Medicine and Geriatrics Wards at the University Hospital (Policlinico) ‘P. Giaccone’ in Palermo, Italy (COMEPA, COVID-19 Medicina Policlinico Palermo), with the main purpose of finding prognostic tools that can be easily used in clinical practice in order to identify patients hospitalized for/with COVID-19 at higher risk of negative o…
“Less invasive” surgery in the treatment of cutaneous chronic ulcers of the lower limb in elderly
2010
The role of treatment of vascular lesions of the legs is very important in the elderly. Pain, inability, bandages, periodicity of medications can seriously interfere with a good quality of life because of the lower compliance of geriatric patients to accept a surgical approach. To allow a new approach to vascular lesions the Authors propose a guideline in which the topic of “less invasive” surgery is underlined based on their pathophysiological causes. Patients affected with lesions of the legs are addressed to the Leg Ulcers Centre by general physicians and selected on the basis of age and comorbility to propose a therapeutical plan. General conditions, evaluation of lesions healing and of…
Uniformization of two-dimensional metric surfaces
2014
We establish uniformization results for metric spaces that are homeomorphic to the Euclidean plane or sphere and have locally finite Hausdorff 2-measure. Applying the geometric definition of quasiconformality, we give a necessary and sufficient condition for such spaces to be QC equivalent to the Euclidean plane, disk, or sphere. Moreover, we show that if such a QC parametrization exists, then the dilatation can be bounded by 2. As an application, we show that the Euclidean upper bound for measures of balls is a sufficient condition for the existence of a 2-QC parametrization. This result gives a new approach to the Bonk-Kleiner theorem on parametrizations of Ahlfors 2-regular spheres by qu…
Endoplasmic Reticulum Stress and miRNA Impairment in Aging and Age-Related Diseases
2021
Aging is a physiological process defined by decreased cellular and tissue functions. Reduced capacity of protein degradation is one of the important hallmarks of aging that may lead to misfolded protein accumulation and progressive loss of function in organ systems. Recognition of unfolded/misfolded protein aggregates via endoplasmic reticulum (ER) stress sensors activates an adaptive mechanism, the unfolded protein response (UPR). The initial step of UPR is defined by chaperone enhancement, ribosomal translation suppression, and misfolded protein degradation, while prolonged ER stress triggers apoptosis. MicroRNAs (miRNAs) are non-coding RNAs affecting various signaling pathways through de…
Formation of microbial organic carbonates during the Late Jurassic from the Northern Tethys (Amu Darya Basin, Uzbekistan): implications for Jurassic …
2020
23 pages; International audience; The Late Jurassic was a period of major global carbon cycle perturbations with episodes of anoxia leading to regional accumulation of organic matter in sediments worldwide. The Tubiegatan section (SW Gissar Mountains, Uzbekistan) located in the Northern Tethys, shows atypical organic-rich limestone and marl deposits (up to 6% of total organic carbon) marked by pronounced negative excursions of δ13Ccarb (amplitude of ca. 12‰) and δ13Corg (amplitude of ca. 4‰) recorded during the Middle Oxfordian (Transversarium Zone). A transdisciplinary approach including sedimentology, palynofacies characterization, mineralogy, organic and inorganic geochemistry was carrie…