Search results for "53"
showing 10 items of 2908 documents
DNA adduct levels associated with p53 induction and delay of MCF-7 cells in S phase after exposure to benzo[g]chrysene dihydrodiol epoxide enantiomer…
1998
Optically active isomers of a mammary carcinogen, anti-benzo[g]chrysene 11, 12-dihydrodiol 13, 14-epoxide, react to different extents with DNA and generate DNA adducts that differ in their stereochemistry. In the study reported here, the effect of these two enantiomers on the progress of human breast carcinoma MCF-7 cells through the cell cycle was investigated. Each enantiomer caused the cells to accumulate in the S phase, but a higher dose of the benzo[g]chrysene 11S, 12R-dihydrodiol 13R, 14S-epoxide than of its enantiomer was required to induce this effect. Similarly, induction of p53 also required a higher dose of benzo[g]chrysene 11S, 12R-dihydrodiol 13R, 14S-epoxide. Postlabeling stud…
Performance of jet substructure techniques for large-$R$ jets in proton-proton collisions at $\sqrt{s}$ = 7 TeV using the ATLAS detector
2013
This paper presents the application of a variety of techniques to study jet substructure. The performance of various modified jet algorithms, or jet grooming techniques, for several jet types and event topologies is investigated for jets with transverse momentum larger than 300 GeV. Properties of jets subjected to the mass-drop filtering, trimming, and pruning algorithms are found to have a reduced sensitivity to multiple proton-proton interactions, are more stable at high luminosity and improve the physics potential of searches for heavy boosted objects. Studies of the expected discrimination power of jet mass and jet substructure observables in searches for new physics are also presented.…
Spectroscopic and electrochemical study of interactions between DNA and different salts of 1,4-dihydropyridine AV-153
2020
1,4-dihydropyridines (1,4-DHP) possess important biochemical and pharmacological properties, including antimutagenic and DNA-binding activity. The latter activity was first described for water-soluble 1,4-DHP with carboxylic group in position 4, the sodium salt of the 1,4-DHP derivative AV-153 among others. Some data show the modification of physicochemical properties and biological activities of organic compounds by metal ions that form the salts. We demonstrated the different affinity to DNA and DNA-protecting capacity of AV-153 salts, depending on the salt-forming ion (Na, K, Li, Rb, Ca, Mg). This study aimed to use different approaches to collate data on the DNA-binding mode of AV-153-N…
Exchange coupling in the correlated electronic states of amorphous GdFe films
2013
The bulk sensitivity of hard x-ray photoelectron spectroscopy in combination with circularly polarized radiation of the P09 beamline at PETRA III enables the investigation of the magnetic properties of capped films. We have determined the temperature dependence of the magnetic circular dichroism in the Fe 2$p$ and in the Gd 3$d$ states in amorphous GdFe films. The magnetic dichroism reflects the stronger temperature dependence of Gd moments compared to Fe moments in agreement with mean-field models. We resolved the exchange split Gd 3${d}_{5/2}$ substates and found a significant temperature dependence of the splitting which is attributed to a temperature dependent part of the exchange energ…
Ciudadanía y enseñanza de la historia. Resultados de una intervención en la formación de maestros
2011
Producción Científica
Nanomagnetic Self-Organizing Logic Gates
2021
The end of Moore's law for CMOS technology has prompted the search for low-power computing alternatives, resulting in several promising proposals based on magnetic logic[1-8]. One approach aims at tailoring arrays of nanomagnetic islands in which the magnetostatic interactions constrain the equilibrium orientation of the magnetization to embed logical functionalities[9-12]. Despite the realization of several proofs of concepts of such nanomagnetic logic[13-15], it is still unclear what the advantages are compared to the widespread CMOS designs, due to their need for clocking[16, 17] and/or thermal annealing [18,19] for which fast convergence to the ground state is not guaranteed. In fact, i…
A Multiplicity result for a class of strongly indefinite asymptotically linear second order systems
2010
We prove a multiplicity result for a class of strongly indefinite nonlinear second order asymptotically linear systems with Dirichlet boundary conditions. The key idea for the proof is to bring together the classical shooting method and the Maslov index of the linear Hamiltonian systems associated to the asymptotic limits of the given nonlinearity.
Concio habita ad ... Clementem VIII ... in Basílica Sancti Petri in Vaticano de refulgenti spiritus S. Adventu Augustissima Pentecostes die anno MDX…
1593
Altres 23 textos. BUV BH Mss. 0634 Grav. amb escut papal a la port. Caplletres historiades i ornades Sign. :A6
Modelling complex dynamics and distributed generation of knowledge with bacterial-based algorithms
2014
Este estudio tuvo como objetivo demostrar que las sociedades conectadas y heterogéneas con intercambios entre pares (P2P) son más resilientes que las centralizadas y homogéneas. En el modelado basado en agentes, se modelizan agentes con racionalidad limitada que interactúan en un entorno común guiado por reglas locales, lo que lleva a Sistemas Adaptativos Complejos (CAS) que se denominan 'sociedades artificiales'. Estos modelos simplificados de sociedades humanas crecen de abajo hacia arriba en entornos computacionales y pueden utilizarse como un laboratorio para probar algunas hipótesis. Hemos demostrado que en un modelo basado en interacciones libres entre agentes autónomos, los resultado…