Search results for "54"
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Libro primero d[e] las epístolas familiares del ... señor don Antonio de Gueuara ... obispo d[e] Mo[n]doñedo ...
1549
Sig. [ ]2, A-O8, P6. - Data d'impr."a nueue dias del mes de março. Año de mil y quinientos y quarenta y nueue Años" I. - CXV [i.e.CXX] f. Escut imperial i escuts episcopals de l'autor a la port. - Capitals grav. Port. amb orla xil., a dos tintes. - Lletra gòtica. - Text amb alguna postil·la marginal. - Tots els f. orlats. - Errates de fol. CXV per CXX
Authigenic phase formation and microbial activity control Zr, Hf, and rare earth element distributions in deep-sea brine sediments
2014
Abstract. Sediments collected from hypersaline and anoxic deep-sea basins in the eastern Mediterranean (Thetis, Kryos, Medee, and Tyro) were characterised in terms of their mineralogical composition, the distributions of rare earth elements (REE), Zr, and Hf and their content of microbial DNA. We identified two major mineralogical fractions: one fraction of detritic origin was composed of quartz, gypsum, and low-Mg calcite bioclasts (with 0 < Mg < 0.07%) and another fraction of authigenic origin constituted of halite, dolomite, high-Mg calcite (with a Mg content of up to 22%) and rare bischofite and showed a textural evidence of microbial assemblages. We found that in the Medee and Ty…
Micro-Economical Aspects of Public Projects: Impact Factors for Project Efficiency and Sustainability
2015
Project management approach in the public administration becoming gradually applied tool for implementation of different public programs and activities. Latvia has several methodological documentations to evaluate the possible benefits from infrastructure but still there is need for improvements as the only clear defined methodology is for transport sectors and those which have been provided by the European commission, but not always have been practically used in local municipalities’ project evaluations. Public projects, and planning for such projects, generally have the following characteristics: • Such projects are inherently risky due to long planning horizons and complex interfaces. • …
The IceCube realtime alert system
2016
Following the detection of high-energy astrophysical neutrinos in 2013, their origin is still unknown. Aiming for the identification of an electromagnetic counterpart of a rapidly fading source, we have implemented a realtime analysis framework for the IceCube neutrino observatory. Several analyses selecting neutrinos of astrophysical origin are now operating in realtime at the detector site in Antarctica and are producing alerts to the community to enable rapid follow-up observations. The goal of these observations is to locate the astrophysical objects responsible for these neutrino signals. This paper highlights the infrastructure in place both at the South Pole detector site and at IceC…
Hypoxia inducible factor-1 alpha expression is increased in infected positive HPV16 DNA oral squamous cell carcinoma and positively associated with H…
2011
Abstract Background There is increasing evidence for the role of High Risk (HR) Human PapillomaVirus (HPV) in the pathogenesis of Oral Squamous Cell Carcinoma (OSCC). The E6 and E7 oncogenes from HR HPVs are responsible for the deregulation of p53 and pRB proteins involved in cell cycle and apoptotic pathways. In cell lines experiments, the HPV E7 protein seems to be able to enhance Hypoxia Inducible Factor-1 alpha (HIF-1α) activity, normally involved in the response to hypoxia and able to enhance angiogenesis. Results We studied tumor specimens from 62 OSCC; a higher prevalence of tumors in TNM stage II and also in pT2 class between OSCC infected positive HPV16 DNA than non-infected ones w…
Non-Thermal Ultrasonic Extraction of Polyphenolic Compounds from Red Wine Lees
2020
This study presents the results of conventional aqueous (CE) and non-conventional ultrasound-assisted (UAE) extractions of polyphenolic compounds from lees extracts of red wine varieties (Merlot and Vranac). The effect of ultrasound extraction time (t, s), and amplitude (A,%) from a 400 W ultrasound processor with different ultrasonic probes diameters (Ds, mm) on the amount and profile of polyphenolic compounds in the obtained extracts was investigated and compared to CE. The optimal conditions resulting in maximum extraction of phenolic compounds were: Probe diameter of 22 mm, amplitude 90% and extraction time for Vranac wine lees 1500 s and for Merlot wine lees extraction time of 1361 s. …
HPLC-SEC: a new approach to characterise complex wastewater effluents
2016
ABSTRACTThis work investigates the use of HPLC-SEC to characterise dissolved organic matter (DOM) of complex wastewater effluents. A silica-based column, sodium acetate eluent and multiple detections were employed: UV-254 absorbance for humictype, and tryptophan-like (Ex/Em = 270/355) and tyrosine-like (Ex/Em = 270/310) fluorescence for protein type compounds. Effects of eluent pH, eluent ionic strength and injection volume on separation efficiency were tested. Humic-type and protein-type fractions were clearly differentiated and eluted within and out of calibration range. Eluent ionic strength had the greatest influence on global resolution; the lowest eluent concentration of 0.01 M produc…
New corological and biological data of the Red Gum Lerp Psyllid, Glycaspis brimblecombei Moore, 1964 in Italy (Hemiptera, Psyllidae)
2011
Glycaspis brimblecombei Moore, 1964 is a psyllid (Hemiptera: Psyllidae) pest of Eucalyptus, native toAustralia and first recorded in Europe: Spain in 2008 and more recently (2010) in Italy. The present paper dealswith recent research, carried out in central Italy, with new data on the distribution and biology of this species.
First-Line Immune Checkpoint Inhibitor-Based Sequential Therapies for Advanced Hepatocellular Carcinoma: Rationale for Future Trials
2021
<b><i>Introduction:</i></b> Atezolizumab (ATEZO) plus bevacizumab (BEVA) represents the new standard of care for the treatment of advanced hepatocellular carcinoma (HCC). However, the choice of the second-line treatment after the failure of immunotherapy-based first-line remains elusive. Taking into account the weaknesses of the available evidence, we developed a simulation model based on available phase III randomized clinical trials (RCTs) to identify optimal risk/benefit sequential strategies. <b><i>Methods:</i></b> A Markov model was built to estimate the overall survival (OS) of sequential first- and second-line systemic treatments. Seque…
"Table 4" of "Inclusive heavy-flavour production at central and forward rapidity in Xe-Xe collisions at $\sqrt {s_{NN}}$=5.44$ TeV"
2021
Transverse momentum differential production of muons from heavy-flavour hadron decays at forward rapidity in Xe-Xe collisions at 5.44 TeV.