Search results for "56"

Predicting who fails to meet the physical activity guideline in pregnancy: a prospective study of objectively recorded physical activity in a populat…

2016

Background A low physical activity (PA) level in pregnancy is associated with several adverse health outcomes. Early identification of pregnant women at risk of physical inactivity could inform strategies to promote PA, but no studies so far have presented attempts to develop prognostic models for low PA in pregnancy. Based on moderate-to-vigorous intensity PA (MVPA) objectively recorded in mid/late pregnancy, our objectives were to describe MVPA levels and compliance with the PA guideline (≥150 MVPA minutes/week), and to develop a prognostic model for non-compliance with the PA guideline. Methods From a multi-ethnic population-based cohort, we analysed data from 555 women with MVPA recorde…

Design, synthesis, and biological evaluation of thiophene analogues of chalcones.

2008

Chalcones are characterized by possessing an enone moiety between two aromatic rings. A series of chalcone-like agents, in which the double bond of the enone system is embedded within a thiophene ring, were synthesized and evaluated for antiproliferative activity and inhibition of tubulin assembly and colchicine binding to tubulin. The replacement of the double bond with a thiophene maintains antiproliferative activity and therefore must not significantly alter the relative conformation of the two aryl rings. The synthesized compounds were found to inhibit the growth of several cancer cell lines at nanomolar to low micromolar concentrations. In general, all compounds having significant anti…

Gestione dell’irrigazione del vigneto attraverso l’uso di modelli di simulazione e misure di campo.

2008

In the paper the applicability of a numerical model, i.e. SWAP (Soil Water Atmosphere Plant), and a functional model, i.e. FAO 56, for irrigation scheduling is assessed. Model validation was initially carried out through the comparison between simulated and measured water content of a soil profile. The two models were then used in order to verify the possibility to simulate the typical irrigation management of the study area. In particular, the attitude of the two models to simulate the number and the distribution of watering, as well as the seasonal water consumption found in the ordinary management irrigation was assessed. Different scenarios of irrigation management allowed the analysis …

Lettera dell' Abate D. Giovanni Andres al nobil uomo sig. marchese Gregorio Filip. Maria. Casali Bentivoglio Paleotti ... : Estratta dal Primo Tomo d…

1779

Ornaments tip. a la port. i al final Sign.: A16 Reclams

Saggio della filosofia del Galileo

Port. amb ornament tip., bandes Sign.: A-M8, N4, [ ]2 Notes a peu de pàg. separades del text per filet Reclams

WT1 isoform expression pattern in acute myeloid leukemia.

2013

WT1 plays a dual role in leukemia development, probably due to an imbalance in the expression of the 4 main WT1 isoforms. We quantify their expression and evaluate them in a series of AML patients. Our data showed a predominant expression of isoform D in AML, although in a lower quantity than in normal CD34+ cells. We found a positive correlation between the total WT1 expression and A, B and C isoforms. The overexpression of WT1 in AML might be due to a relative increase in A, B and C isoforms, together with a relative decrease in isoform D expression.

Targeting Aberrant Ncam (neural cell adhesion molecule; CD56) Expression in Acute Myeloid Leukemia

2015

Abstract Background Acute myeloid leukemia (AML) is a heterogeneous disease of the hematopoietic progenitor cell driven by the subsequent acquisition of genetic alterations. Approximately 20% of AML patients show strong expression of CD56 (neural cell adhesion molecule; NCAM). Expression of NCAM is associated with poor overall survival; however, the functional role of aberrant NCAM expression has not been investigated to date. The goal of this study is to examine the biological role of NCAM in AML and to explore whether NCAM represents a potential therapeutic target. Results In order to evaluate the clinical significance of elevated NCAM expression in AML, we screened a panel of human cell …

Synthesis of dimethyl carbonate in supercritical carbon dioxide

2006

The reactivity of carbon dioxide with methanol to form dimethyl carbonate was studied in the presence of the n-butylmethoxytin compounds n-Bu3SnOCH3, n-Bu2Sn(OCH3)2 , and [n-Bu2(CH3O)Sn]2 O. The reaction occurred under solventless conditions at 423 K and was produced by an increase in CO2 pressure. This beneficial effect is primarily attributed to phase behavior. The mass transfer under liquid-vapor biphasic conditions was not limiting when the system reached the supercritical state for a CO2 pressure higher than 16 MPa. Under these conditions, CO2 acted as a reactant and a solvent.

Post-mortem enamel surface texture alteration during taphonomic processes—do experimental approaches reflect natural phenomena?

2022

Experimental approaches are often used to better understand the mechanisms behindand consequences of post-mortem alteration on proxies for diet reconstruction.Dental microwear texture analysis (DMTA) is such a dietary proxy, using dental wearfeatures in extant and extinct taxa to reconstruct feeding behaviour and mechanicalfood properties. In fossil specimens especially, DMTA can be biased by post-mortemalteration caused by mechanical or chemical alteration of the enamel surface. Herewe performed three different dental surface alteration experiments to assess the effectof common taphonomic processes by simplifying them: (1) tumbling in sedimentsuspension to simulate fluvial transport, (2) s…

A new Meckel's cartilage from the Devonian Hangenberg black shale in Morocco and its position in chondrichthyan jaw morphospace.

2022

Fossil chondrichthyan remains are mostly known from their teeth, scales or fin spines only, whereas their cartilaginous endoskeletons require exceptional preservational conditions to become fossilized. While most cartilaginous remains of Famennian (Late Devonian) chondrichthyans were found in older layers of the eastern Anti-Atlas, such fossils were unknown from the Hangenberg black shale (HBS) and only a few chondrichthyan teeth had been found therein previously. Here, we describe a Meckel’s cartilage from the Hangenberg black shale in Morocco, which is the first fossil cartilage from these strata. Since no teeth or other skeletal elements have been found in articulation, we used elliptica…