Search results for "57"

Effective treatment of allergic airway inflammation with Helicobacter pylori immunomodulators requires BATF3-dependent dendritic cells and IL-10

2014

The prevalence of allergic asthma and other atopic diseases has reached epidemic proportions in large parts of the developed world. The gradual loss of the human indigenous microbiota has been held responsible for this trend. The bacterial pathogen Helicobacter pylori is a constituent of the normal gastric microbiota whose presence has been inversely linked to allergy and asthma in humans and experimental models. Here we show that oral or i.p. tolerization with H. pylori extract prevents the airway hyperresponsiveness, bronchoalveolar eosinophilia, pulmonary inflammation, and Th2 cytokine production that are hallmarks of allergen-induced asthma in mice. Asthma protection is not conferred by…

Developments in pediatrics in 2020: choices in allergy, autoinflammatory disorders, critical care, endocrinology, genetics, infectious diseases, micr…

2021

AbstractIn this article, we describe the advances in the field of pediatrics that have been published in the Italian Journal of Pediatrics in 2020. We report progresses in understanding allergy, autoinflammatory disorders, critical care, endocrinology, genetics, infectious diseases, microbiota, neonatology, neurology, nutrition, orthopedics, respiratory tract illnesses, rheumatology in childhood.

Contribución de Anales de Pediatría a la visibilidad internacional de la investigación pediátrica española en la Web of Science (2010-2014)

2016

Resumen: Objetivo: Describir el papel de Anales de Pediatría en la difusión de la investigación pediátrica española e identificar las revistas con las que compite internacionalmente. Material y método: Se identificó la producción pediátrica española y la de Anales de Pediatría recogida en la categoría Pediatrics del Science Citation Index de la WoS (2010-2014) analizando su volumen y tipo documental. De los artículos originales y revisiones (artículos) se estudiaron el año, la citación y el tipo de revista de publicación (revistas generales y especializadas). De las generales, se analizó su productividad de acuerdo con su idioma, posición que ocupa en los JCR de 2012 y accesibilidad a sus c…

The Raven's Coloured Progressive Matrices in Healthy Children: A Qualitative Approach

2020

Studies on the structure of intelligence refer to two main theoretical models: the first one considers intelligence as a unitary construct, the second one assumes the involvement of a plurality of factors. Studies using Raven’s Coloured Progressive Matrices (RCPM) tasks have often highlighted the involvement of different cognitive abilities and brain structures, but in the clinical setting, RCPM measurement continues to be used as a single score. The current study aimed to analyse the RCPM performance following qualitative clustering, in order to provide an interpretation of the intelligence assessment through a factorial criterion. The RCPM have been administered to a large group of typica…

Affinity Sensors for the Diagnosis of COVID-19

2021

The coronavirus disease 2019 (COVID-19) outbreak caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was proclaimed a global pandemic in March 2020. Reducing the dissemination rate, in particular by tracking the infected people and their contacts, is the main instrument against infection spreading. Therefore, the creation and implementation of fast, reliable and responsive methods suitable for the diagnosis of COVID-19 are required. These needs can be fulfilled using affinity sensors, which differ in applied detection methods and markers that are generating analytical signals. Recently, nucleic acid hybridization, antigen-antibody interaction, and change of reactive oxyge…

Vēsture: Latvijas Universitātes Žurnāls, Nr.11/12

2021

I Vaticana fragmenta a due secoli dalla riscoperta

2022

Two centuries have passed since the palimpsest that transmits a Roman legal work known as the Vaticana fragmenta was rediscovered by Angelo Mai in the Vatican Apostolic Library in Rome. This paper reviews the main issues relating to this work and suggests some reasons why a new edition of the text is desirable. 1820 hat Angelo Mai in der Vatikanischen Apostolischen Bibliothek in Rom ein Palimpsest wiederentdeckt, welches ein römisches Rechtswerk – die so genannte Vaticana Fragmenta – überliefert. 200 Jahre sind seitdem genau vergangen. Dieser Beitrag gibt einen Überblick über die wichtigsten Aspekte dieses Werks und zeigt Gründe auf, warum eine neue Ausgabe dieses Textes wünschenswert ist.

Transcriptome data reveal syndermatan relationships and suggest the evolution of endoparasitism in acanthocephala via an epizoic stage

2014

The taxon Syndermata comprises the biologically interesting wheel animals ("Rotifera": Bdelloidea + Monogononta + Seisonidea) and thorny-headed worms (Acanthocephala), and is central for testing superordinate phylogenetic hypotheses (Platyzoa, Gnathifera) in the metazoan tree of life. Recent analyses of syndermatan phylogeny suggested paraphyly of Eurotatoria (free-living bdelloids and monogononts) with respect to endoparasitic acanthocephalans. Data of epizoic seisonids, however, were absent, which may have affected the branching order within the syndermatan clade. Moreover, the position of Seisonidea within Syndermata should help in understanding the evolution of acanthocephalan endoparas…

Use of running plates by floor housed rats: A pilot study

2021

The outfit of husbandry facilities of, and the enrichment provided for, experimental rodents plays an important role in the animals’ welfare, and hence also for the societal acceptance of animal experiments. Whether rats and mice benefit from being provided with running wheels or plates is discussed controversially. Here we present observations from a feeding experiment, where rats were provided a running plate. As a pilot study, six identical cages, with three animals per cage, were filmed for six days, and the resulting footage was screened for the number of bouts and the time the animals spent on the plates. The main activities observed on the plate in descending order were sitting (18.…

Loss of density-dependence and incomplete control by dominant breeders in a territorial species with density outbreaks

2011

Abstract Background A territory as a prerequisite for breeding limits the maximum number of breeders in a given area, and thus lowers the proportion of breeders if population size increases. However, some territorially breeding animals can have dramatic density fluctuations and little is known about the change from density-dependent processes to density-independence of breeding during a population increase or an outbreak. We suggest that territoriality, breeding suppression and its break-down can be understood with an incomplete-control model, developed for social breeders and social suppression. Results We studied density dependence in an arvicoline species, the bank vole, known as a terri…