Search results for "65"

Social innovation in a post-conflict setting : examining external factors affecting social service NGOs

2021

While the study of the influence of external environmental factors on non-governmental organizations (NGOs) is well explored in the international development literature, the importance of these factors on NGOs’ transformative roles in a post-conflict development setting remains less understood. Nevertheless, external environmental factors could have a crucial impact on NGOs in such a context, especially when NGOs want to integrate a socially innovative approach into the social services they provide. Using survey data of staff members of social service NGOs from post-conflict Bosnia and Herzegovina (N = 120) and applying resource dependence theory, this study identifies three environmental f…

AGE6. Skin Ageing: Focus on the Role of Inflammatory Genetic Factors in Cutaneous Neoplasia

2014

AGE6. Skin Ageing: Focus on the Role of Inflammatory Genetic Factors in Cutaneous Neoplasia C. M. Gambino1, F. Crapanzano1, G. Accardi1, A. Aiello1, C. Virruso1, G. Pistone1, M. R. Bongiorno1, D. Lio1, C. R. Balistreri1, G. Candore1 1University of Palermo, Palermo, Italy Background: Skin aging is a complex process that involves intrinsic and exogenous causes. Photo-oxidative damage caused by UV is the leading cause of extrinsic aging of the skin, known as photo-ageing. UV damages can be linked mostly to overproduction of ROS that induces a complex molecular cascade able to accelerate physiological aging, determining a typical dermal/epidermal inflammation with an increased risk of getting s…

Safety of Tyrosine Kinase Inhibitors in Patients With Differentiated Thyroid Cancer: Real-World Use of Lenvatinib and Sorafenib in Korea

2019

Background: Thyroid cancer has become the most common cancer in Korea. Generally, thyroid cancer patients have a good prognosis; however, 15–20% of patients experience recurrence or distant metastasis or are refractory to standard treatment. We assessed the safety of sorafenib and lenvatinib in patients with advanced or metastatic radioactive iodine-refractory differentiated thyroid cancers (DTC) consecutively treated at a tertiary center in South Korea.Methods: We retrospectively reviewed the charts of all consecutive patients with DTC treated during ≥6 months with lenvatinib (February 2016–April 2018) and sorafenib (January 2014–April 2018) at Gangnam Severance Hospital. Patients were tre…

Brief an Johann Gottfried Herder

1797

ETAT TOPOLOGIQUE DE L'ESPACE TEMPS A L'ECHELLE 0

2002

We propose in this research a new solution regarding the existence and the content of the initial spacetime singularity. In the context of topological field theory we consider that the initial singularity of space-time corresponds to a zero size singular gravitational instanton characterized by a Riemannian metric configuration (++++) in dimension D = 4. Connected with some unexpected topological data corresponding to the zero scale of space-time, the initial singularity is thus not considered in terms of divergences of physical fields but can be resolved in the frame of topological field theory. We get this result from the physical observation that the pre-spacetime is in a thermal equilib…

Understanding family dynasty: Nurturing the corporate identity across generations

2010

This study aims to analyse the Ahlstrom annual reports. The content analysis contributes to family business corporate identity. According to the results family business corporate identity is based both on history and on the future. Human resource management, customer relationships, high quality, and also family ownership reflect corporate identity in large family corporations. Modern family business corporate identity is based on continuously developing the business concept and its core competency. Meeting the needs of customers and technical quality standards combined with upgrading and developing the business idea characterises family business corporate identity. peerReviewed

Nèstor NOVELL i Josep SORRIBES: Nou Viatge pel País Valencià Universitat d'Alacant, Universitat de València i Institució Alfons el Magnànim, 2017, 15…

2018

La inscripción de la ciudadanía en la cuba neocolonial (1902-1919) : Sucinta referencia histórico-jurídica

2021

This historical-legal account brieflycovering 17 years of civil registration activity carried out during the neocolonial period by Municipal Judges and Secretaries, specifically that related to registration of Cuban citizens)becomes considerably relevant to understand and to godeeper into the origins of this complex process, as well asto achieve a re-encounter with the history of those who passed through those times, currently a hidden history in the shadows of Civil Registration offices, but still alive and thus allowing us to find all the beauty that there was in it.

Realization of time-resolved two-vacuum-ultraviolet-photon ionization

2009

International audience; Ultrafast dynamics of excited molecules is studied through time-resolved two-vacuum-ultraviolet (vuv)- photon ionization using a nonlinear volume autocorrelator unit. The two-vuv-photon process is induced by the intense fifth harmonic radiation of a femtosecond Ti:sapphire laser. In a proof-of-principle experiment, ultrafast dynamics of excited ethylene and oxygen molecules are investigated. Molecular decay times are deduced by comparing the experimental data with the results of a numerical model that accounts for the spatial and temporal characteristics of the harmonic field. The present experiments pave a convenient way for time domain investigations in the vuv-xuv s…

Tryptophan Metabolic Pathways and Brain Serotonergic Activity: A Comparative Review

2019

The essential amino acid L-tryptophan (Trp) is the precursor of the monoaminergic neurotransmitter serotonin (5-hydroxytryptamine, 5-HT). Numerous studies have shown that elevated dietary Trp has a suppressive effect on aggressive behavior and post-stress plasma cortisol concentrations in vertebrates, including teleosts. These effects are believed to be mediated by the brain serotonergic system, even though all mechanisms involved are not well understood. The rate of 5-HT biosynthesis is limited by Trp availability, but only in neurons of the hindbrain raphe area predominantly expressing the isoform TPH2 of the enzyme tryptophan hydroxylase (TPH). In the periphery as well as in brain areas …