Search results for "6th century"

Nuove riflessioni sul canone teatrale del madrigale drammatico

2012

The article deals with some case studies on theatrical spectacles with music, as the “mascherate” composed by Orazio Vecchi in Modena. Further, it examines some excerpts of the sixteenth-century Italian polyphony, which have not written for the stage, thus recreating the musical landscape inspired by popular songs and the onomatopoeic lexicon drawn from pastoral dramas and comedies before Vecchi’s "Amphiparnaso" (1597). In the second part, applying the criteria of narratology, the author analyses the works of Alessandro Striggio ("Il cicalamento delle donne al bucato", 1567), Gaspare Torelli ("I fidi amanti", 1600) and Adriano Banchieri ("La pazzia senile", 1607 2edn., "La prudenza giovenil…

The face of conflict: Significant sharp force trauma to the mid-facial skeleton in an individual of probable 16th–17th century date excavated from By…

2016

A variety of injuries have always been associated with violence, consequences of which people had to deal with. In this paper we present a complex of craniofacial and dental injuries resulted from sharp force trauma. The basis of our study was historical skeletal material excavated from archeological site in Byczyna (11th–17th century), Poland. An individual whose skeleton was exhumed from the grave No. 610 exhibited healed, oblique trauma of the left maxilla, damage to the crowns of right central and lateral incisors and concomitant luxation of the right maxillary central incisor. We describe the mechanism of this trauma and complications that resulted from damage to the masticatory appara…

Deregulation of the G1 to S-phase cell cycle checkpoint is involved in the pathogenesis of human osteosarcoma.

2004

Osteosarcoma (OS) displays complex karyotypes with numerical changes as well as structural abnormalities suggesting that several oncogenes and tumor suppressor genes may be implicated in the biology of OS. The aim of our study was to investigate the possible implication of the molecular alterations of the G1 to S-phase checkpoint genes in the pathogenesis of OS. We analyzed samples from 29 patients and found molecular alterations of the RB and TP53 genes in 6 (21%) and 3 (10%) cases, respectively. Homozygous deletion of the INK4A/ARF locus and methylation of INK4A was detected in 3 (10%) and 2 (7%) cases, respectively. CDK4 and MDM2 co-amplification was observed in 1 case (3%). Cyclin D3 is…

Giovanni Filippo Ingrassia: A five-hundred year-long lesson.

2010

Giovanni Filippo Ingrassia was born five centuries ago in Regalbuto, a small town in the center of Sicily. After his medical course in Padua, under the guidance of Vesalius and Fallopius, he gained international fame as a physician and was recruited as a Professor of human anatomy in Naples and later in Palermo. He is remembered as "the new Galen" or "the Sicilian Hippocrates." He contributed to the knowledge of human anatomy through the description of single bones rather than the whole skeleton. In particular, he was the first to describe the "stapes," the "lesser wings of the sphenoid" and various other structures in the head (probably the pharyngotympanic tube) as well as in the reproduc…

Yersinia pestis DNA from Skeletal Remains from the 6th Century AD Reveals Insights into Justinianic Plague

2013

Yersinia pestis, the etiologic agent of the disease plague, has been implicated in three historical pandemics. These include the third pandemic of the 19th and 20th centuries, during which plague was spread around the world, and the second pandemic of the 14th–17th centuries, which included the infamous epidemic known as the Black Death. Previous studies have confirmed that Y. pestis caused these two more recent pandemics. However, a highly spirited debate still continues as to whether Y. pestis caused the so-called Justinianic Plague of the 6th–8th centuries AD. By analyzing ancient DNA in two independent ancient DNA laboratories, we confirmed unambiguously the presence of Y. pestis DNA in…

Exposure to elevated temperatures and risk of preterm birth in Valencia, Spain

2014

Abstract Background Prematurity is the second-leading cause of death in children under the age of 5 worldwide. It is predicted that the future climate will have more intense, longer lasting and frequent extreme heat episodes, and so the temperature effect on the risk of preterm birth is generating considerable interest in the public health field. Our aim was to explore the potential short-term effects of elevated temperatures on the risk of preterm birth in Valencia (Spain). Methods All singleton natural births born in the metropolitan area of Valencia during the warm season (May–September, 2006–2010) were included ( N =20,148). We applied time-series quasi-Poisson generalized additive mode…

First Published Record of a Neurosurgical Procedure on the North American Continent, Mexico City, by Pedro Arias de Benavides, 1561:Secretos de Chiru…

2000

The first published account of a neurosurgical intervention performed on the North American continent is described. The operation took place in Mexico City in 1561. The neurosurgical intervention was performed by a Spanish surgeon, Pedro Arias de Benavides, on a 13-year-old boy who had sustained head trauma that caused an open depressed cranial fracture and exposed the cerebrum. A description of this case was first published in Valladolid, Spain, 6 years after the event, in a book entitled Secretos de Chirurgia ("Secrets of Surgery").

Molecular evidence of HLA-B27 in a historical case of ankylosing spondylitis

2005

Maestri e cantieri nella Sicilia interna tra XV e XVI secolo: le chiese Madri di Pietraperzia e Assoro

2014

The essay focuses on two yards of the interior of Sicily between the end of the fifteenth century and the first half of the sixteenth century: the mother church of Pietraperzia and that of Assoro. New documentary investigations allowed to set out the master builders involved in the construction process and to deduce some construction methods in use for churches basilica. These data, together with the direct observation of the buildings have allowed to hypothesize, in both cases, the original configuration of the churches. The hypotheses were supported by a comparison with contemporary building, similar to typological characteristics, and a re-reading of the archival documents referring to t…

Negociación, guerra y "asientos". Financiar el elército de Flandes en el último tercio del reinado de Felipe II (1577-1596)

2019

El periodo comprendido entre 1575 y 1596 fue enormemente complejo a nivel político en los Países Bajos y no lo fue menos a nivel financiero para el ejército de Flandes. Estos años estuvieron enmarcados entre dos suspensiones de pagos en los que las negociaciones financieras fueron determinantes para la guerra en los Países Bajos, donde se dirimió la hegemonía hispánica en la Europa del siglo xVI. Estas negociaciones, que se dieron tanto a nivel global como a nivel local, fueron esenciales pagar conseguir aprovisionar al ejército de Flandes y mantener, por extensión, el dominio político y militar en los Países Bajos. Monarquía, ?asientos? y hombres de negocios crearon un cuerpo indivisible q…