Search results for "70"
showing 10 items of 9933 documents
The PROMISE study protocol: a multicenter prospective study of process optimization with interdisciplinary and cross-sectoral care for German patient…
2021
Background and purpose — Knee and hip replacement are common and increasing procedures, and an optimized care process that could be implemented in different settings would be useful. The PROMISE trial investigates whether a new care process works equally in different German settings and how the results compare with current non-standardized care. Patients and methods — This multi-center prospective mixed-method study includes 2,000 German patients receiving arthritis-related hip or knee endoprostheses. An interdisciplinary and cross-sectoral care process was developed and implemented in 3 German hospitals with different levels of care, and corresponding rehabilitation centers were included t…
Impingement of the Sciatic Nerve due to a Protruding Acetabular Cage Rim
2020
Abstract Sciatic nerve damage is a well-known complication that occurs in 1.5% of patients after primary total hip arthroplasty and in 8% after revision total hip arthroplasty. Yet when considering re-revision arthroplasty and acetabular cage implantation, incidence and management remain unclear. This case report describes a young female patient with sciatic nerve impingement after acetabular cage implantation. Her primary complaint was shooting sciatic left leg pain, worsening on ambulation and when seated. A complete workup was negative for spinal impingement or infection, and axonal nerve damage was confirmed through nerve conduction studies. The intraoperative findings showed that it wa…
Joint contractures in the absence of inflammation may indicate mucopolysaccharidosis
2009
Abstract Background Undiagnosed patients with the attenuated form of mucopolysaccharidosis (MPS) type I often have joint symptoms in childhood that prompt referral to a rheumatologist. A survey conducted by Genzyme Corporation of 60 European and Canadian rheumatologists and pediatric rheumatologists demonstrated that Bone and joint manifestations are prominent among most patients with MPS disorders. These life-threatening lysosomal storage diseases are caused by deficient activity of specific enzymes involved in the degradation of glycosaminoglycans. Patients with attenuated MPS disease often experience diagnostic delays. Enzyme replacement therapy is now commercially available for MPS I (l…
Regulation of Apoptosis by Inhibitors of Apoptosis (IAPs).
2013
Abstract Inhibitors of Apoptosis (IAPs) are a family of proteins with various biological functions including regulation of innate immunity and inflammation, cell proliferation, cell migration and apoptosis. They are characterized by the presence of at least one N-terminal baculoviral IAP repeat (BIR) domain involved in protein-protein interaction. Most of them also contain a C-terminal RING domain conferring an E3-ubiquitin ligase activity. In drosophila, IAPs are essential to ensure cell survival, preventing the uncontrolled activation of the apoptotic protease caspases. In mammals, IAPs can also regulate apoptosis through controlling caspase activity and caspase-activating platform format…
Systematic Use of Song and Music in Dementia Care: Health Care Providers’ Experiences
2020
Background and Aim Using song and music in a systematic way in residential dementia care may have several positive impacts on the patients, as well as the care providers. The aim of this study was to explore how health care providers experienced taking responsibility for conducting a song and music program in dementia care in nursing homes. Methods An explorative, qualitative study design was used. Focus groups were formed by 17 health care providers from 3 different nursing homes. These providers had experience implementing and using the “Gjenklang” (“reverberation”) song and music program especially developed for people with dementia. Focus group interviews were transcribed verbatim, and …
Musikkterapi for mennesker med rusmiddelproblematikk: En kvalitativ metasyntese om erfaringer og opplevelser
2018
Masteroppgave klinisk helsevitenskap ME520 - Universitetet i Agder 2018 Background: Music therapy and other music-based therapies have become common in Norwegian mental health and drug misuse treatments in recent years. There are studies indicating that music therapy has good effect on this patient group. There is recommendation from the Norwegian Directorate of Health that music therapy should be offered in drug rehabilitation programs. However, little research exists on how people with substance abuse problems experience this form of therapy. Aim: This study aims to compare existing research of the experiences of people with substance abuse problems with music therapy. Research-question: …
Meu caro amigo Lucio, Ciao
2012
Quando eu era criança, imaginava que tudo na Itália tinha o cheiro e a forma das músicas de Lucio Dalla. Do primeiro Lucio Dalla. Hoje, Dalla representa um pouco a imagem triste da decadência da parte mais bela do país onde escolhi viver. Um pouco como aquelas virgens deprimidas e infelizes que a religião católica impõe aos seus fiéis. Na gênese, Lucio Dalla era de esquerda, genial, "malgré lui". Em 1976, pouco antes que eu nascesse, seu amigo Chico Buarque, que o tinha conhecido quando exilado na Itália, lhe escreveu uma carta sobre um Brasil em plena ditadura. Uma das músicas mais visionarias da historia da MPB: "Meu Caro Amigo".
Variants of the
2019
The Gram-positive soil bacterium Bacillus subtilis relies on the glutamine synthetase and the glutamate synthase for glutamate biosynthesis from ammonium and 2-oxoglutarate. During growth with the carbon source glucose, the LysR-type transcriptional regulator GltC activates the expression of the gltAB glutamate synthase genes. With excess of intracellular glutamate, the gltAB genes are not transcribed because the glutamate-degrading glutamate dehydrogenases (GDHs) inhibit GltC. Previous in vitro studies revealed that 2-oxoglutarate and glutamate stimulate the activator and repressor function, respectively, of GltC. Here, we have isolated GltC variants with enhanced activator or repressor fu…
Erratum: De Teresa, J.M. et al. Comparison between Focused Electron/Ion Beam-Induced Deposition at Room Temperature and under Cryogenic Conditions. M…
2020
In Section 3 [...]
Associations of physical performance and physical activity with mental well-being in middle-aged women
2021
Abstract Background To investigate whether physical performance is independently of physical activity (PA) associated with positive and negative dimensions of mental well-being in middle-aged women. Methods Data were drawn from the Estrogenic Regulation of Muscle Apoptosis (ERMA) study in which women 47 to 55 years were randomly selected from the Finnish National Registry. They (n = 909) participated in measurements of physical performance (handgrip force, knee extension force, vertical jumping height, maximal walking speed, and six-minute walking distance). Both mental well-being (the Centre for Epidemiologic Studies Depression Scale, the International Positive and Negative Affect Schedule…