Search results for "74"

Effect of mismatch repair on the mutation rate of bacteriophage ϕX174

2015

Viral mutation rates vary widely in nature, yet the mechanistic and evolutionary determinants of this variability remain unclear. Small DNA viruses mutate orders of magnitude faster than their hosts despite using host-encoded polymerases for replication, which suggests these viruses may avoid post-replicative repair. Supporting this, the genome of bacteriophage ϕX174 is completely devoid of GATC sequence motifs, which are required for methyl-directed mismatch repair in Escherichia coli . Here, we show that restoration of the randomly expected number of GATC sites leads to an eightfold reduction in the rate of spontaneous mutation of the phage, without severely impairing its replicative capa…

Critica scientifica, popolarizzazione dell’etnografia ed etica dell’antropologo: sulla “controversia yanomami”, per esempio

2021

La “controversia sugli Yanomami” ha investito questioni centrali, tanto epistemologiche quanto etiche e politiche, per la disciplina e la pratica dell’antropologia, riguardando in particolare l’etica della ricerca sul campo; il modo di impiegare i dati di ricerca per sostenere determinate ipotesi teoriche; i rapporti tra popolarizzazione e politicizzazione delle ricerche e, più in generale, la responsabilità degli antropologi rispetto sia agli usi dei loro studi nella sfera pubblica sia nei confronti dei soggetti umani con cui lavorano. In quest’articolo esamino alcuni momenti chiave della “controversia”. In particolare provo a ricostruire il modo in cui si è inizialmente consolidata, dentr…

Usurpacion de los Estados del Papa por Buonaparte, ó coleccion de los papeles de oficio relativos a esta materia, publicados por orden de la Corte de…

Sign.: [A]2, B-I2 Notes a peu de pàg

A systematic review of animal models for experimental neuroma

2015

Summary Peripheral neuromas can result in an unbearable neuropathic pain and functional impairment. Their treatment is still challenging, and their optimal management is to be defined. Experimental research still plays a major role, but - although numerous neuroma models have been proposed on different animals - there is still no single model recognised as being the reference. Several models show advantages over the others in specific aspects of neuroma physiopathology, prevention or treatment, making it unlikely that a single model could be of reference. A reproducible and standardised model of peripheral neuroma would allow better comparison of results from different studies. We present a…

PALERMO NEL QUADERNO DI VIAGGIO IN SICILIA DI NICODEMUS TESSIN (1674)

2019

In 1674 the Swedish architect Nicodemus Tessin the Younger, during his short journey to Sicily, visited Palermo, where he stayed only for three days. Yet he had the opportunity to spend some of his time visiting the city and keeping a journal, a notebook characterized by concise writing, but where brief notes of whatever he found interesting or peculiar elements (such as monuments, marble statues and fountains, architectural furniture ecc.) and therefore the journal witnesses indeed what a young XVIIth century architect, destined to the future role of royal architect, could select and choose.Tessin's further observations are directed towards painting, along with extremely useful information…

Zvaigžņotā Debess: 2004/05, Ziema

2004

Contents: Ņ.Ozoliņa. Earthquakes in Latvia ; I.Daube. Space Craft “Ranger-7” ; M. Gailis. Moon Investigation in Riga ; J.Tambergs. Problems of Dialogue between Quantum Mechanics and Theology (concluded) ; Z Alksne, A.Alksnis. Ultra-Cool Dwarf Pair Weighed ; A.Balklavs. Successful Hunt of Protostars ; A.Balklavs. Silhouette of a Black Hole ; A.Balklavs. A Distant Giant Quasar ; A.Balklavs. Cosmic Objects in Captivating Photos – 3 ; J.Freimanis. Extragalactic Planetary Nebulae ; J.Jaunbergs. Cassini Enters the Saturnian System ; D.Krieviņš. Space Launchers of Early XXI Century. The Commonwealth of Independent States (CIS) ; J.Bārzdiņš. Professor Rusins-Martins Freivalds on the Path of Science…

Dynamically generated resonances from the vector octet-baryon octet interaction

2010

We study the interaction of vector mesons with the octet of stable baryons in the framework of the local hidden gauge formalism using a coupled-channels unitary approach. We examine the scattering amplitudes and their poles, which can be associated to known J(P) = 1/2(-), 3/2(-) baryon resonances, in some cases, or give predictions in other ones. The formalism employed produces doublets of degenerate J(P) = 1/2(-), 3/2(-) states, a pattern which is observed experimentally in several cases. The findings of this work should also be useful to guide present experimental programs searching for new resonances, in particular in the strange sector where the current information is very poor.

The clinical impact of donor-specific antibodies in heart transplantation.

2018

Donor-specific antibodies (DSA) are integral to the development of antibody-mediated rejection (AMR). Chronic AMR is associated with high mortality and an increased risk for cardiac allograft vasculopathy (CAV). Anti-donor HLA antibodies are present in 3-11% of patients at the time of heart transplantation (HTx), with de novo DSA (predominantly anti-HLA class II) developing post-transplant in 10-30% of patients. DSA are associated with lower graft and patient survival after HTx, with one study suggesting a three-fold increase in mortality in patients who develop de novo DSA (dnDSA). DSA against anti-HLA class II, notably DQ, are at particularly high risk for graft loss. Although detection o…

Comparison of E-Trust and Trust Concepts in Online and Offline Dimensions

2017

Abstract In everyday lives, we more and more use different technology products to make our lives easier and faster. We often do not realise that we are switching our lifestyles to the online platform - we do everything mostly online - meet and communicate with others, watch videos and listen to favourite songs, choose and buy different things. The main question is - can we trust everything that we see on the screen? Is the explanation of “trust” the same in real life and in online sphere? Authors of the paper compare the concept of “trust” in offline trade market with that in online trading. The following methods were used - literature study and analysis, consumer survey and statistical ana…

Revealing Employer’s Name in Social Networks

2017

Abstract The research investigates the question of the importance of mentioning the name of the employer in online and offline social networks. The exchange of information is an important part of social networks and social capital theory. Companies can use the networks of their employees to recruit new hires and to check habits and interests of likely new employees. To do that, the employee has to mention the name of the company in these social networks. The paper compares different real social networks used by family and friends and private and business social network sites (SNSs) as online social networks and compares the differences between men and women. The empirical research has been …