Search results for "78"
showing 10 items of 1163 documents
Vēsture: Latvijas Universitātes Žurnāls, Nr.11/12
2021
Antibacterial PEGylated Solid Lipid Microparticles for Cosmeceutical Purpose: Formulation, Characterization, and Efficacy Evaluation
2020
The development of efficacious means of delivering antioxidant polyphenols from natural sources for the treatment of skin diseases is of great interest for many cosmetic and pharmaceutical companies. Resveratrol (RSV) and Limonene (LIM) have been shown to possess good anti-inflammatory and antibacterial properties against Staphylococcus aureus infections responsible for many skin disorders, such as acne vulgaris. In this study, solid lipid microparticles are designed as composite vehicles capable of encapsulating a high amount of trans-RSV and enhancing its absorption through the stratum corneum. A microparticulate system based on mixture of PEGylate lipids, long-chain alcohols and LIM is a…
Differential in vitro Anti-HIV Activity of Natural Lignans
1990
Abstract Two naturally occurring lignanolides, isolated from the tropical climbing shrub Ipomoea cairica, (-)-arctigen in and (-)-trachelogen in , were found to inhibit strongly replication of human immunodeficiency virus type 1 (HIV-1; strain HTLV-III B) in vitro. At a concentration of 0.5 (μм , (-)-arctigenin and (-)-trachelogenin inhibited the expression of HIV-1 proteins p 17 and p24 by 80 -90 % and 60 -70 % , respectively. The reverse transcriptase activity in the culture fluids was reduced by 80 -90 % when the cells (HTLV-III B/H 9) were cultivated in the presence of 0.5 μм (-)-arctigen in or 1 μм (-)-trachelogenin . At the same concentrations, the formation of syncytia in the HTLV-I…
Alianzas, ambiciones y ascenso de dos familias de la élite concejil orensana en 1680-1746: los Armada y Araúxo, y los Salgado y Gundín
2020
Linear and cyclic radio k-labelings of trees
2007
International audience; Motivated by problems in radio channel assignments, we consider radio k-labelings of graphs. For a connected graph G and an integer k ≥ 1, a linear radio k-labeling of G is an assignment f of nonnegative integers to the vertices of G such that |f(x)−f(y)| ≥ k+1−dG(x,y), for any two distinct vertices x and y, where dG(x,y) is the distance between x and y in G. A cyclic k-labeling of G is defined analogously by using the cyclic metric on the labels. In both cases, we are interested in minimizing the span of the labeling. The linear (cyclic, respectively) radio k-labeling number of G is the minimum span of a linear (cyclic, respectively) radio k-labeling of G. In this p…
Stress concentration for closely located inclusions in nonlinear perfect conductivity problems
2019
We study the stress concentration, which is the gradient of the solution, when two smooth inclusions are closely located in a possibly anisotropic medium. The governing equation may be degenerate of $p-$Laplace type, with $1<p \leq N$. We prove optimal $L^\infty$ estimates for the blow-up of the gradient of the solution as the distance between the inclusions tends to zero.
Functional Fibronectin Adsorption on Aptamer-Doped Chitosan Modulates Cell Morphology by Integrin-Mediated Pathway.
2019
A decisive step in cell-biomaterial interaction is represented by the adsorption of proteins at the interface, whose fine control may be useful to trigger proper cell response. To this purpose, we can selectively control protein adsorption on biomaterials by means of aptamers. Aptamers selected to recognize fibronectin dramatically enhance chitosan ability to promote cell proliferation and adhesion, but the underlying biological mechanism remains unknown. We supposed that aptamers contributed to ameliorate the adsorption of fibronectin in an advantageous geometrical conformation for cells, thus regulating their morphology by the proper activation of the integrin-mediated pathway. We investi…
Sources of geomaterials in the Sicani Mountains during the Early Middle Ages: A case study of Contrada Castro, central western Sicily
2022
From 2017, an unknown rural settlement in Contrada Castro at Corleone (Palermo Province, western Sicily) was investigated as part of the `Harvesting Memories Project¿. The stratigraphic sequence, supported by radiocarbon dating, has demonstrated a reoccupation of a pre-Roman site during the transition between the Byzantine and Islamic periods. In particular, the main occupation occurred in the late 8th¿9th century when pottery kilns and a probable warehouse were constructed. During the 10th¿11th century, a new structure with different orientations replaced the previous buildings that had already collapsed. Specifically focusing on a perspective of the household production and its relationsh…
La factoría de la Empresa Nacional Elcano en Manises : una valoración patrimonial
2010
La factoría de la Empresa Nacional Elcano de Manises (Valencia) fue construida entre 1946 y 1953 dentro de los planes estatales de reconstrucción industrial de la postguerra. Sus arquitecturas plantean una dualidad entre la modernidad y racionalidad de los espacios productivos y la tradición historicista de los edificios representativos, directamente relacionada con los programas ideológicos del Régimen. De su valoración a partir de los criterios establecidos por el Ministerio de Cultura para el Plan Nacional de Patrimonio Industrial, se desprende el extraordinario valor de la factoría como conjunto, el cual se sitúa por encima de la ya alta calidad de sus edificios a nivel individual, por …
DeepEva: A deep neural network architecture for assessing sentence complexity in Italian and English languages
2021
Abstract Automatic Text Complexity Evaluation (ATE) is a research field that aims at creating new methodologies to make autonomous the process of the text complexity evaluation, that is the study of the text-linguistic features (e.g., lexical, syntactical, morphological) to measure the grade of comprehensibility of a text. ATE can affect positively several different contexts such as Finance, Health, and Education. Moreover, it can support the research on Automatic Text Simplification (ATS), a research area that deals with the study of new methods for transforming a text by changing its lexicon and structure to meet specific reader needs. In this paper, we illustrate an ATE approach named De…