Search results for "85"
showing 10 items of 1612 documents
Liminaalitilan käsite työn muutosten jäsentäjänä
2013
Liminaalitila on antropologiassa määritelty välitilaksi, kynnyksellä olemiseksi. Liminaalisuus on nykypäivän työelämälle ominainen piirre, joka voi näyttäytyä kaaoksena, mutta myös uutta luovana muutosvaiheena.
$\Lambda_c^{\pm}$ production in pp collisions with a new fragmentation function
2020
Physical review / D D 101(11), 114021 (2020). doi:10.1103/PhysRevD.101.114021
Performance of the ALICE experiment at the CERN LHC
2014
ALICE is the heavy-ion experiment at the CERN Large Hadron Collider. The experiment continuously took data during the first physics campaign of the machine from fall 2009 until early 2013, using proton and lead-ion beams. In this paper we describe the running environment and the data handling procedures, and discuss the performance of the ALICE detectors and analysis methods for various physics observables.
Caracterización funcional de mutaciones oncogénicas de PI3K
2015
El cáncer es una enfermedad compleja originada por alteraciones genéticas en proto-oncogenes y/o supresores tumorales. El proto-oncogén PI3K se encuentra alterado en numerosos cánceres. La PI3K de clase I son quinasas, formadas por una subunidad catalítica (p110) y una reguladora (p85), que catalizan la conversión de PtdIns(4,5)P2 en PtdIns(3,4,5)P3 en las membranas celulares. Este último es un segundo mensajero que recluta a la quinasa de Ser/Thr AKT, la cual activa a numerosos efectores y desencadena una respuesta proliferativa y de supervivencia celular, por lo que mutaciones que causen la hiperactivación de esta ruta conllevan la transformación de células normales en células tumorales. …
Location-Awareness for Failure Management in Cellular Networks: An Integrated Approach
2021
Recent years have seen the proliferation of different techniques for outdoor and, especially, indoor positioning. Still being a field in development, localization is expected to be fully pervasive in the next few years. Although the development of such techniques is driven by the commercialization of location-based services (e.g., navigation), its application to support cellular management is considered to be a key approach for improving its resilience and performance. When different approaches have been defined for integrating location information into the failure management activities, they commonly ignore the increase in the dimensionality of the data as well as their integration into th…
El impacto de la política de visados sobre los flujos internacionales de turistas: Un análisis con datos de panel
2016
Using newly panel data on visa restrictions for the years 2000 and 2010 in a theory-grounded gravity model, we find a robust, causal negative impact of visa restrictions on international tourist flows. By destination, the detrimental impact of this type of barrier is observed for tourists going to developing countries (with the exception of East and South Asia), but not for those to developed ones. By country of origin of tourists, the impact of visa restrictions appears to be the same for tourists coming from developed and developing countries. These findings have important consequences in policy terms for tourism management at a regional level.
Children’s Fruit and Vegetable Preferences Are Associated with Their Mothers’ and Fathers’ Preferences
2021
Children’s preference for fruit and vegetables must emerge during childhood. At children’s homes, mothers and fathers influence children’s developing food preferences with their own preferences and actions. The purpose of the study was to reveal the association parents have with their children’s fruit and vegetable preferences. The study was conducted in a sample of Finnish mothers and fathers of 3–5-year-old children. The participants were recruited, and questionnaires distributed through early childhood education and care centers in 2014 and 2015. The results showed considerable variance in the children’s preferences, and were more similar with their father’s, than their mother’s preferen…
Intergenerational Effect of Early Life Exposure to Permethrin: Changes in Global DNA Methylation and in Nurr1 Gene Expression
2015
Environmental exposure to pesticides during the early stages of development represents an important risk factor for the onset of neurodegenerative diseases in adult age. Neonatal exposure to Permethrin (PERM), a member of the family of synthetic pyrethroids, can induce a Parkinson-like disease and cause some alterations in striatum of rats, involving both genetic and epigenetic pathways. Through gene expression analysis and global DNA methylation assessment in both PERM-treated parents and their untreated offspring, we investigated on the prospective intergenerational effect of this pesticide. Thirty-three percent of progeny presents the same Nurr1 alteration as rats exposed to permethrin i…
New Evidence of the Enhanced Elimination of a Persistent Drug Used as a Lipid Absorption Inhibitor by Advanced Oxidation with UV-A and Nanosized Cata…
2019
This work demonstrates new evidence of the efficient destruction and mineralization of an emergent organic pollutant using UV-A and titanium nanosized catalysts. The target compound considered in this work is the primary metabolite of a lipid regulator drug, clofibrate, identified in many studies as refractory during conventional wastewater treatment. The photocatalytic performance study was carried out in batch mode at laboratory scale, in aqueous suspension. Kinetic data showed that titanium dioxide P25 Aeroxide® exhibits the highest photocatalytic efficiency compared to the other investigated catalysts. Pollutant degradation and mineralization efficiencies strongly increased when decreas…
Effect of Sex, Body Mass Index and Physical Activity Level on Peak Oxygen Uptake Among 14–19 Years Old Adolescents
2020
The aim was to describe longitudinal trends in peak oxygen uptake (VO2peak) among 14- to 19-year-old adolescents in Norway, and to examine effects of sex, body mass index (BMI), and physical activity (PA) level on VO2peak during adolescence. Of 124 invited students from two lower secondary schools in Norway, 116 eighth-grade students (61 boys and 55 girls; 14 years old at baseline) volunteered to participate. The study has a longitudinal design with 6 yearly repeated measures of body height and mass, VO2peak and PA level. VO2peak allometrically scaled to body mass raised to the power of 0.67 was measured using a walking or running incremental test on a treadmill, whereas PA level was self-r…